Results 71 to 80 of about 28,883 (156)

On Botulinum Neurotoxin Variability

mBio, 2015
The rapidly growing number of botulinum neurotoxin sequences poses the problem of the possible evolutionary significance of the variability of these superpotent neurotoxins for toxin-producing Clostridium species. To progress in the understanding of this
Cesare Montecucco, Maria Berica Rasotto
doaj   +1 more source

Inhibition of Membrane Na+ Channels by A Type Botulinum Toxin at Femtomolar Concentrations in Central and Peripheral Neurons

Journal of Pharmacological Sciences, 2012
Recent studies have demonstrated that the botulinum neurotoxins inhibit the release of acetylcholine, glutamate, GABA, and glycine in central nerve system (CNS) neurons.
Min-Chul Shin, Masahito Wakita, Du-Jie Xie, Toshitaka Yamaga, Satomi Iwata, Yasushi Torii, Tetsuhiro Harakawa, Akihiro Ginnaga, Shunji Kozaki, Norio Akaike   +9 more
doaj   +1 more source

Environmental influences in the global incidence of attention deficit/hyperactivity disorder and autism spectrum disorder: A longitudinal analysis of historical trends (2010-2021) across 204 countries [PDF]

Journal of Health and Social Sciences
Introduction: The global incidence of Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD) may be shaped by social and environmental factors.
Livio TARCHI, Annalisa DI GIACOMO, Tiziana PISANO, Valdo RICCA, Giovanni CASTELLINI, Kavita BATRA, Amelia RIZZO, Hicham KHABBACHE, Francesco CHIRICO   +8 more
doaj   +1 more source

Clostridial neurotoxins

, 2002
Tetanus (TeNT) and botulinum (BoNTs) neurotoxins are powerful toxins endowed with a specific zinc-endopeptidase activity. Targets of these neurotoxins have been identified as synaptic members of the SNARE proteins, which are involved in the exocytosis of
Bohnert, S., Meunier, F. A., Lalli, G., Verastegui, C., Schiavo, G.   +4 more
core   +1 more source

Prediction of presynaptic and postsynaptic neurotoxins by combining various Chou’s pseudo components

Scientific Reports, 2017
Presynaptic and postsynaptic neurotoxins are two groups of neurotoxins. Identification of presynaptic and postsynaptic neurotoxins is an important work for numerous newly found toxins.
Haiyan Huo, Tao Li, Shiyuan Wang, Yingli Lv, Yongchun Zuo, Lei Yang   +5 more
doaj   +1 more source

The zebrafish model for the study of neurotoxins mechanisms

, 2009
The zebrafish model for the study of neurotoxins ...
RIGONI, MICHELA, ARGENTON, FRANCESCO, TISO, NATASCIA, PETRON M, MONTECUCCO C., ROSSETTO O, MAGNABOSCO A   +6 more
core  

Sequence homology between HIV gp120, rabies virus glycoprotein, and snake venom neurotoxins. Is the nicotinic acetylcholine receptor an HIV receptor?

, 1990
We have found a striking homology between the sequence 164-174 of HIV-1 gp120 and the sequence 30-40 of snake venom neurotoxins; this sequence homology is very similar to that existing between the same region of snake venom neurotoxins and rabies virus ...
Neri, Paolo, Rustici, M., Bracci, Luisa, Santucci, Annalisa   +3 more
core   +1 more source

Therapeutic applications of botulinum neurotoxins in head and neck disorders

, 2015
ObjectiveThe aim of this article is to review the mechanism of action, physiological effects, and therapeutic applications of botulinum neurotoxins in the head and neck area.Study designAn extensive literature search was performed using keywords.
Timothy Osborn, Mohammed Nadershah, Ahmad Alshadwi   +2 more
core   +1 more source

Investigating Genetic Diversity and Correlations Between Mineral Concentration and Neurotoxin (β-ODAP) Content in the Lathyrus Genus

Plants
Grass pea (Lathyrus sativus L.) is a nutritious legume crop well-adapted to fragile agro-ecosystems that can survive under challenging climatic conditions.
Fadoua Abdallah, Zakaria Kehel, Mohamed Amine El Kalchi, Ahmed Amri, Adil el Baouchi, Zine El Abidine Triqui, Moez Amri, Shiv Kumar   +7 more
doaj   +1 more source

On the role of endogenous neurotoxins and neuroprotection in Parkinson's disease.

, 2018
On the role of endogenous neurotoxins and neuroprotection in Parkinson's disease.
Juan Segura-Aguilar (5616284)
core   +1 more source