Results 31 to 40 of about 291,313 (279)
Synchrony in a presynaptic population leads to correlations in vesicle occupancy at the active sites for neurotransmitter release. The number of independent release sites per presynaptic neuron, a synaptic parameter recently shown to be modifed during ...
Alexander David Bird +2 more
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Exocytosis is one of the essential steps for chemical signal transmission between neurons. In this process, vesicles dock and fuse with the plasma membrane and release the stored neurotransmitters through fusion pores into the extracellular space, and ...
Yuying Liu +5 more
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Many Studies suggest that changes in sympathetic nerve activity in the central nervous system might have a crucial role in blood pressure control. The present paper discusses evidence in support of the concept that the brain renin-angiotensin system (RAS)
Kazushi Tsuda
doaj +1 more source
RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses
All synapses require fusion-competent vesicles and coordinated Ca2+-secretion coupling for neurotransmission, yet functional and anatomical properties are diverse across different synapse types.
Marisa M Brockmann +13 more
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A Phenomenological Synapse Model for Asynchronous Neurotransmitter Release
Neurons communicate with each other via synapses. Action potentials cause release ofneurotransmitters at the axon terminal. Typically, this neurotransmitter release is tightly time-locked to the arrival of an action potential and is thus called ...
Tao eWang +8 more
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The suitability of a newly developed cell-based functional assay was tested for the detection of the activity of a range of neurotoxins and neuroactive pharmaceuticals which act by stimulation or inhibition of calcium-dependent neurotransmitter release ...
Andrea Pathe-Neuschäfer-Rube +2 more
doaj +1 more source
Neurotransmitter release is mediated by the SNARE complex, but the role of its phosphorylation has scarcely been elucidated. Although PKC activators are known to facilitate synaptic transmission, there has been a heated debate on whether PKC mediates ...
Norikazu Katayama +6 more
doaj +1 more source
Sympathetic nerve-derived ATP regulates renal medullary vasa recta diameter via pericyte cells: a role for regulating medullary blood flow? [PDF]
Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins.
Crawford, C. +4 more
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Molecular mechanisms driving homeostatic plasticity of neurotransmitter release
Homeostatic plasticity is a process by which neurons adapt to the overall network activity to keep their firing rates in a reasonable range. At the cellular level this kind of plasticity comprises modulation of cellular excitability and tuning of ...
Vesna eLazarevic +3 more
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Developmental synaptic changes at the transient olivocochlear-inner hair cell synapse [PDF]
In the mature mammalian cochlea, inner hair cells (IHCs) are mainly innervated by afferent fibers that convey sound information to the CNS. During postnatal development, however, medial olivocochlear (MOC) efferent fibers transiently innervate the IHCs ...
Elgoyhen, Ana Belen +5 more
core +1 more source

