Results 21 to 30 of about 195,340 (251)
Nature Communications, 2021 Synaptotagmin 1 (Syt1) is the calcium sensor for fast synchronous neurotransmitter release but the mechanism by which it functions is still under debate.
Sarah B. Nyenhuis +7 more
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Frontiers in Computational Neuroscience, 2014 Synchrony in a presynaptic population leads to correlations in vesicle occupancy at the active sites for neurotransmitter release. The number of independent release sites per presynaptic neuron, a synaptic parameter recently shown to be modifed during ...
Alexander David Bird +2 more
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International Journal of Hypertension, 2012 Many Studies suggest that changes in sympathetic nerve activity in the central nervous system might have a crucial role in blood pressure control. The present paper discusses evidence in support of the concept that the brain renin-angiotensin system (RAS)
Kazushi Tsuda
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RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses
eLife, 2019 All synapses require fusion-competent vesicles and coordinated Ca2+-secretion coupling for neurotransmission, yet functional and anatomical properties are diverse across different synapse types.
Marisa M Brockmann +13 more
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Frontiers in Chemistry, 2021 Exocytosis is one of the essential steps for chemical signal transmission between neurons. In this process, vesicles dock and fuse with the plasma membrane and release the stored neurotransmitters through fusion pores into the extracellular space, and ...
Yuying Liu +5 more
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A Phenomenological Synapse Model for Asynchronous Neurotransmitter Release
Frontiers in Computational Neuroscience, 2016 Neurons communicate with each other via synapses. Action potentials cause release ofneurotransmitters at the axon terminal. Typically, this neurotransmitter release is tightly time-locked to the arrival of an action potential and is thus called ...
Tao eWang +8 more
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Toxins, 2021 The suitability of a newly developed cell-based functional assay was tested for the detection of the activity of a range of neurotoxins and neuroactive pharmaceuticals which act by stimulation or inhibition of calcium-dependent neurotransmitter release ...
Andrea Pathe-Neuschäfer-Rube +2 more
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The Role of Neurotrophins in Neurotransmitter Release [PDF]
The Neuroscientist, 2002 The neurotrophins (NTs) have recently been shown to elicit pronounced effects on quantal neurotransmitter release at both central and peripheral nervous system synapses. Due to their activity dependent release, as well as the subcellular localization of both protein and receptor, NTs are ideally suited to modify the strength of ...
William J, Tyler +2 more
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Scientific Reports, 2017 Neurotransmitter release is mediated by the SNARE complex, but the role of its phosphorylation has scarcely been elucidated. Although PKC activators are known to facilitate synaptic transmission, there has been a heated debate on whether PKC mediates ...
Norikazu Katayama +6 more
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Cell Reports, 2023 Summary: Rapid release of neurotransmitters in synchrony with action potentials is considered a key hardwired property of synapses. Here, in glutamatergic synapses formed between induced human neurons, we show that action potential-dependent ...
Burak Uzay +5 more
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