Results 31 to 40 of about 1,558,949 (288)

Recent Progress in Quantitatively Monitoring Vesicular Neurotransmitter Release and Storage With Micro/Nanoelectrodes

open access: yesFrontiers in Chemistry, 2021
Exocytosis is one of the essential steps for chemical signal transmission between neurons. In this process, vesicles dock and fuse with the plasma membrane and release the stored neurotransmitters through fusion pores into the extracellular space, and ...
Yuying Liu   +5 more
doaj   +1 more source

Presynaptic mechanisms determining the dynamic range of neurotransmitter release in the lateral amygdala [PDF]

open access: yes, 2008
The amygdala is a central brain structure receiving sensory information from diverse regions of the central nervous system. Cortical and thalamic axons converge to the lateral amygdala (LA) which is thought to be the main site for fear-induced ...
Fourcaudot, Elodie
core   +1 more source

Cell-Based Reporter Release Assay to Determine the Activity of Calcium-Dependent Neurotoxins and Neuroactive Pharmaceuticals

open access: yesToxins, 2021
The suitability of a newly developed cell-based functional assay was tested for the detection of the activity of a range of neurotoxins and neuroactive pharmaceuticals which act by stimulation or inhibition of calcium-dependent neurotransmitter release ...
Andrea Pathe-Neuschäfer-Rube   +2 more
doaj   +1 more source

The Role of Neurotrophins in Neurotransmitter Release [PDF]

open access: yesThe Neuroscientist, 2002
The neurotrophins (NTs) have recently been shown to elicit pronounced effects on quantal neurotransmitter release at both central and peripheral nervous system synapses. Due to their activity dependent release, as well as the subcellular localization of both protein and receptor, NTs are ideally suited to modify the strength of ...
William J, Tyler   +2 more
openaire   +2 more sources

Serotonin, how to find it... [PDF]

open access: yes, 2013
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Biochemically derived from tryptophan, serotonin is primarily found in the gastrointestinal tract, platelets, and in the central nervous system (CNS) of animals, including humans ...
Crespi, Francesco
core   +1 more source

SNAP-25 phosphorylation at Ser187 regulates synaptic facilitation and short-term plasticity in an age-dependent manner

open access: yesScientific Reports, 2017
Neurotransmitter release is mediated by the SNARE complex, but the role of its phosphorylation has scarcely been elucidated. Although PKC activators are known to facilitate synaptic transmission, there has been a heated debate on whether PKC mediates ...
Norikazu Katayama   +6 more
doaj   +1 more source

Dueling Ca2+ Sensors in Neurotransmitter Release [PDF]

open access: yes, 2011
Ca2+-triggered neurotransmitter release is characterized by two kinetically distinct components: a fast synchronous phase and a slow asynchronous phase. Yao et al.
Giagtzoglou, Nikolaos   +5 more
core   +1 more source

Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging

open access: yesCell Reports, 2023
Summary: Rapid release of neurotransmitters in synchrony with action potentials is considered a key hardwired property of synapses. Here, in glutamatergic synapses formed between induced human neurons, we show that action potential-dependent ...
Burak Uzay   +5 more
doaj   +1 more source

Electrical properties of dendrites relevant to dendritic transmitter release

open access: yes, 2005
The dendritic geometry, the passive membrane properties, and the densities, distribution and kinetics of voltage-gated channels together determine the compartmentalization of electrical signals in dendrites, and how these electrical compartments interact.
Häusser, Michael, Roth, Arnd
core   +1 more source

Molecular mechanisms driving homeostatic plasticity of neurotransmitter release

open access: yesFrontiers in Cellular Neuroscience, 2013
Homeostatic plasticity is a process by which neurons adapt to the overall network activity to keep their firing rates in a reasonable range. At the cellular level this kind of plasticity comprises modulation of cellular excitability and tuning of ...
Vesna eLazarevic   +3 more
doaj   +1 more source

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