Results 31 to 40 of about 1,558,949 (288)
Exocytosis is one of the essential steps for chemical signal transmission between neurons. In this process, vesicles dock and fuse with the plasma membrane and release the stored neurotransmitters through fusion pores into the extracellular space, and ...
Yuying Liu +5 more
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Presynaptic mechanisms determining the dynamic range of neurotransmitter release in the lateral amygdala [PDF]
The amygdala is a central brain structure receiving sensory information from diverse regions of the central nervous system. Cortical and thalamic axons converge to the lateral amygdala (LA) which is thought to be the main site for fear-induced ...
Fourcaudot, Elodie
core +1 more source
The suitability of a newly developed cell-based functional assay was tested for the detection of the activity of a range of neurotoxins and neuroactive pharmaceuticals which act by stimulation or inhibition of calcium-dependent neurotransmitter release ...
Andrea Pathe-Neuschäfer-Rube +2 more
doaj +1 more source
The Role of Neurotrophins in Neurotransmitter Release [PDF]
The neurotrophins (NTs) have recently been shown to elicit pronounced effects on quantal neurotransmitter release at both central and peripheral nervous system synapses. Due to their activity dependent release, as well as the subcellular localization of both protein and receptor, NTs are ideally suited to modify the strength of ...
William J, Tyler +2 more
openaire +2 more sources
Serotonin, how to find it... [PDF]
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Biochemically derived from tryptophan, serotonin is primarily found in the gastrointestinal tract, platelets, and in the central nervous system (CNS) of animals, including humans ...
Crespi, Francesco
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Neurotransmitter release is mediated by the SNARE complex, but the role of its phosphorylation has scarcely been elucidated. Although PKC activators are known to facilitate synaptic transmission, there has been a heated debate on whether PKC mediates ...
Norikazu Katayama +6 more
doaj +1 more source
Dueling Ca2+ Sensors in Neurotransmitter Release [PDF]
Ca2+-triggered neurotransmitter release is characterized by two kinetically distinct components: a fast synchronous phase and a slow asynchronous phase. Yao et al.
Giagtzoglou, Nikolaos +5 more
core +1 more source
Summary: Rapid release of neurotransmitters in synchrony with action potentials is considered a key hardwired property of synapses. Here, in glutamatergic synapses formed between induced human neurons, we show that action potential-dependent ...
Burak Uzay +5 more
doaj +1 more source
Electrical properties of dendrites relevant to dendritic transmitter release
The dendritic geometry, the passive membrane properties, and the densities, distribution and kinetics of voltage-gated channels together determine the compartmentalization of electrical signals in dendrites, and how these electrical compartments interact.
Häusser, Michael, Roth, Arnd
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Molecular mechanisms driving homeostatic plasticity of neurotransmitter release
Homeostatic plasticity is a process by which neurons adapt to the overall network activity to keep their firing rates in a reasonable range. At the cellular level this kind of plasticity comprises modulation of cellular excitability and tuning of ...
Vesna eLazarevic +3 more
doaj +1 more source

