Results 131 to 140 of about 210,121 (261)
Dietary protein improves flesh quality by enhancing antioxidant ability via the NF-E2-related factor 2/Kelch-like ECH-associated protein 1 signaling pathway in softshell turtle (Pelodiscus sinensis). [PDF]
Front Nutr, 2022 Kou H +8 more
europepmc +1 more source
Low- and high-dose hydrogen peroxide regulation of transcription factor NF-E2-related factor 2.
Chinese medical journal, 2010 Reactive oxygen species (ROS) may play both physiological and pathophysiological roles. Transcription factor NF-E2-related factor 2 (Nrf2) regulates antioxidant response element (ARE)-mediated genes expression and coordinates induction of chemoprotective proteins in response to physical and chemical stresses.
Jiao-lin, Ning, Li-wen, Mo, Xi-nan, Lai
openaire +1 more source
Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer
Medicinal Research Reviews, EarlyView.ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek +3 more
wiley +1 more source
Development of a secreted cell-permeable NF-κB inhibitor to control inflammation [PDF]
, 2010 PhDRheumatoid arthritis (RA) is an autoimmune chronic inflammatory disease, of unknown aetiology. Several disease-modulating approaches have been developed in the past years, however these are expensive, usually accompanied by unwanted side-effects ...
Koutsokeras, Apostolos
core
Role of p52 (NF-κB2) in LPS tolerance in a human B cell line [PDF]
, 1999 Cells of the weakly CD14 positive human B cell line RPMI 8226, clone 1, will mobilize NF-κB (p50/p65 and p50/p50) proteins and produce TNF mRNA when stimulated with lipopolysaccharide (LPS), When such cells are precultured with a low amount of LPS (50 ...
Wedel, Angela +13 more
core +1 more source
Scientific ReportsThis study aims to investigate whether alpinetin prevents lipopolysaccharide/D-galactosamine (LPS/D-GalN)-induced acute liver injury (ALI) in mice by inhibiting ferroptosis, and to explore the potential molecular mechanisms involved. Thirty-six male BALB/
Yujia Liu +4 more
doaj +1 more source
Senotherapeutics for Knee Osteoarthritis
Medicinal Research Reviews, EarlyView.ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman +6 more
wiley +1 more source
Journal of Medicine and Life Science, 2009 Isoacteoside was isolated from Clerdendron trichotomum Thunb that belongs to Verbenaceae family. We found that isoacteoside the heme oxygenase-1 (HO-1) expression in a time dependent manner, Furthermore, isoacteoside increased the expression of NF-E2 regulated factor 2 (Nrf2), which is a transcription factor of HO-1, in a time dependent manner ...
Dong Ok Ko, Kyoung Ah Kang, Jin Won Hyun
openaire +1 more source
Moisture Effects on the Dimensional Stability of Bistable Carbon/Epoxy Laminates
Polymer Composites, EarlyView.Experimental and numerical approach for studying moisture effects on composite dimensional stability. ABSTRACT Bistable composite laminates are attractive because they can switch between two stable shapes without continuous energy input, enabling applications in morphing structures and energy harvesting devices.
Andrea Dei Sommi +3 more
wiley +1 more source
MOLECULAR MODELLING STUDIES OF THE NF-κB BIOLOGICAL SYSTEM AS RELEVANT DRUG TARGET [PDF]
, 2009 Background Virtual screening (VS) is now a well-established method for finding small molecular modulators of a biological relevant macromolecule function by using much older computational techniques, such as docking simulations.
Piccagli, Laura
core