Results 71 to 80 of about 34,567,041 (234)

Multifunctional Manganese Oxide Nanocomposite Hydrogel With Synergistic Reactive Oxygen Species‐Scavenging, Oxygen‐Generating, Immunomodulatory, and Photothermal Antimicrobial Activities for Enhanced Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
CFP/PC@MnO2 hydrogel integrates ROS scavenging, oxygen delivery, oxidative stress reduction, immunomodulation, and photothermal antibacterial properties. The incorporation of PC@MnO2 NPs endows the hydrogel with multiple functional advantages tailored to the pathological microenvironment of diabetic wounds, including efficient ROS clearance, mitigation
Zhi Xu   +9 more
wiley   +1 more source

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States

open access: yesAdvanced Science, EarlyView.
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton   +13 more
wiley   +1 more source

Expression and Significance of Nrf2 and Its Target Genes in Pulmonary Adenocarcinoma A549 Cells Resistant to Cisplatin

open access: yesChinese Journal of Lung Cancer, 2009
Background and objective Nuclear factor erythroid-2 related factor 2 (Nrf2) is a key transcription factor in oxidation-reduction reaction. It has been proved that Nrf2 is relevant to cisplatin-resistance in ovarian cancer cells. Up to now, little is know
Kairu ZHANG   +4 more
doaj  

nf-core_bytesize_ nf-core_hgtseq.mp4

open access: yes, 2023
Francesco Lescai presents the nf-core pipeline hgtseq. nf-core/hgtseq is a bioinformatics best-practice analysis pipeline built to investigate horizontal gene transfer from NGS data.
nf-core (9523169)
core   +1 more source

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

open access: yesAdvanced Science, EarlyView.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl   +20 more
wiley   +1 more source

Fisetin Inhibits Osteoclastogenesis Through Prevention of RANKL-Induced ROS Production by Nrf2-Mediated Up-regulation of Phase II Antioxidant Enzymes

open access: yesJournal of Pharmacological Sciences, 2013
.: Osteoclasts (OCLs) are multinucleated bone-resorbing cells that are differentiated by stimulation with receptor activator of nuclear factor kappa-B ligand (RANKL) and macrophage colony-stimulating factor.
Eiko Sakai   +8 more
doaj   +1 more source

nf-core_dualrnaseq (nf-core_bytesize #31).mp4

open access: yes, 2022
Presentation about the nf-core/dualrnaseq pipeline in a special edition of nf-core/bytesize focussed on ...
nf-core (9523169)
core   +1 more source

Heat‐to‐Electricity Conversion Using Barium Strontium Titanate Multilayer Capacitors

open access: yesAdvanced Science, EarlyView.
Lead‐free barium strontium titanate multilayer capacitors convert waste heat into electricity via the Olsen electro‐thermodynamic cycle. These capacitors achieve an energy density of 3.7 J cm−3, comparable to the performance of lead‐based ceramics. Their high dielectric strength and broad operating temperature window below 100°C make them practical for
Fan Ni   +10 more
wiley   +1 more source

Development of a secreted cell-permeable NF-κB inhibitor to control inflammation [PDF]

open access: yes, 2010
PhDRheumatoid arthritis (RA) is an autoimmune chronic inflammatory disease, of unknown aetiology. Several disease-modulating approaches have been developed in the past years, however these are expensive, usually accompanied by unwanted side-effects ...
Koutsokeras, Apostolos
core   +4 more sources

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy