Strategies based on nido-carborane embedded indole fluorescent polymers: their synthesis, spectral properties and cell imaging studies [PDF]
Frontiers in ChemistryThe continuous preparation scheme EPO-Poly-indol-nido-carborane (E-P-INDOLCAB), L100-55-Poly-indol-nido-carborane (L-P-INDOLCAB), RS-Poly-indol-nido-carborane (S-P-INDOLCAB), and RL-Poly-indol-nido-carborane (R-P-INDOLCAB) were used to prepare the four ...
Guofan Jin, Jin Guofan
exaly +4 more sources
Polymeric nanomaterials encapsulating fluorescent polyindole-nido- carborane: design, synthesis and biological evaluation [PDF]
Frontiers in ChemistryThe water-soluble nido-carborane was prepared by alkali treatment of o-carborane. A polymer PInd containing a polyindole structure was synthesized and employed to label the modified o-carborane. Subsequently, four polymeric nanomaterials were synthesized
Shihe Shao
exaly +4 more sources
Synthesis of Zwitter-Ionic Conjugate of Nido-Carborane with Cholesterol [PDF]
Molecules, 2021 9-HC≡CCH2Me2N-nido-7,8-C2B9H11, a previously described carboranyl terminal alkyne, was used for the copper(I)-catalyzed azide-alkyne cycloaddition with azido-3β-cholesterol to form a novel zwitter-ionic conjugate of nido-carborane with cholesterol ...
Anna A. Druzina +6 more
doaj +2 more sources
Charge-Compensated Derivatives of Nido-Carborane
Inorganics, 2023 This review summarizes data on the main types of charge-compensated nido-carborane derivatives. Compared with organic analogs, onium derivatives of nido-carborane have increased stability due to the stabilizing electron-donor action of the boron cage ...
Marina Stogniy +2 more
exaly +3 more sources
Synthesis of Novel Planar-Chiral Charge-Compensated nido-Carborane-Based Amino Acid [PDF]
MoleculesAmino acids with unusual types of chirality and their derivatives have recently attracted attention as precursors in the synthesis of chiral catalysts and peptide analogues with unique properties.
Dmitry A. Gruzdev +5 more
doaj +2 more sources
Preparation and cell imaging of a nido-carborane fluorescent complex based on multi-component polymerization. [PDF]
PLoS ONEThe biocompatibility of carborane was a difficult problem that had drawn a lot of study interest. Using multi-ion inlay binding, water-soluble polymers were created by encapsulating nido-carborane in diazaspirodecaniums such as para-poly-nido ...
Hezhong Ouyang, Zhou Wang, Min Liu
doaj +2 more sources
An Approach Toward Radioiodination and Radiopharmacological Evaluation of a Carborane-Containing Analog of Indomethacin [PDF]
MoleculesDicarbadodecaboranes (12) (carboranes) are versatile molecular building blocks with unique properties, which allow the expansion of classical medicinal-chemical space. To enable single-photon emission computed tomography (SPECT) imaging of cyclooxygenase-
Jonas Schädlich +8 more
doaj +2 more sources
The Far Side of Carboranes: Anticancer Active Monocations and Ambiently Stable Dications. [PDF]
Angew Chem Int Ed EnglThis work describes the synthesis of bench‐stable dicationic carboranes. Their enhanced electrophilicity is documented by opening the clusters with weak nucleophiles or dihydrogen. The surprising stability of positively charged carboranes in water enabled a study of their in vitro antiproliferative activity, which surpassed the effects of doxorubicin ...
Němec V +10 more
europepmc +3 more sources
Structure-Activity Relationships of closo- and nido-Carborane Erlotinib Analogs: Lipophilicity as a Key Modulator of Anti-Glioma Activity [PDF]
PharmaceuticalsBackground/Objectives: To enhance the anti-glioma activity of erlotinib, we previously developed a series of carborane-based analogs exploiting the concept of three-dimensional bioisosterism.
Belén Dávila +8 more
doaj +2 more sources
Emerging agents for boron neutron capture therapy: Biomolecular carriers paving the way for precision radiotherapy. [PDF]
Precis Radiat OncolBoron neutron capture therapy (BNCT) requires key non‐negotiable technical criteria: megadose administration, precise tumor‐specific targeting, favorable biocompatibility, and sustained tumor retention. Overcoming these interconnected challenges fundamentally depends on biomolecular carriers, which are critical for translating the therapeutic potential
Chen C +6 more
europepmc +2 more sources