Results 11 to 20 of about 12,404 (251)
PHOSPHONATED ISOXAZOLIDINYL NUCLEOSIDES, A NEW CLASS OF MODIFIED NUCLEOSIDES [PDF]
Euromediterranean Biomedical Journal, 2014 This review offers an overview of the synthesis of phosphonated isoxazolidinyl nucleosides, a new class of interesting and potentially antiviral/antitumor agents.
Salvatore Giofrè
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Frontiers in Cellular Neuroscience, 2021 Nitrones are potent antioxidant molecules able to reduce oxidative stress by trapping reactive oxygen and nitrogen species. The antioxidant potential of nitrones has been extensively tested in multiple models of human diseases. Sensorineural hearing loss
Isabel Varela-Nieto +11 more
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A new role of N-arylbenzoquinoneimine N-oxides in the von Richter reaction [PDF]
Journal of the Serbian Chemical Society, 2006 The title nitrones react with cyanide ions to give benzoic acids and N-aryl-4-hydroxy-2-cyanophenylamines via two different pathways.
Karami Bahador +3 more
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Amidinoquinoxaline-Based Nitrones as Lipophilic Antioxidants
Antioxidants, 2021 The potential of nitrones (N-oxides) as therapeutic antioxidants is due to their ability to counteract oxidative stress, mainly attributed to their action as radical scavengers toward C- and O-centered radicals.
Nadia Gruber +6 more
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Biocompatible Chemistry: A Plug-and-Play Toolbox for Chemical Biology Research. [PDF]
ChembiochemThe “plug‐and‐play” nature of biocompatible chemistry makes it a powerful toolbox for investigating complicated biological systems and producing drug leads for clinical usages. This review summarizes the commonly used biocompatible reactions and the recent advances of their representative applications in chemical biology research, thus highlighting the
Lovato AR, Lin Z, Zheng Q.
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Antioxidants, 2021 Synthetic nitrone spin-traps are being explored as therapeutic agents for the treatment of a wide range of oxidative stress-related pathologies, including but not limited to stroke, cancer, cardiovascular, and neurodegenerative diseases. In this context,
Stefania Marano +8 more
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Detection of reactive oxygen and nitrogen species by electron paramagnetic resonance (EPR) technique [PDF]
, 2017 During the last decade there has been growing interest in physical-chemical oxidation processes and the behavior of free radicals in living systems. Radicals are known as intermediate species in a variety of biochemical reactions.
Gurer-Orhan, H., Saso, L., Suzen, S.
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Science Journal of University of Zakho, 2023 Synthetic approached towards the synthesis of some novel nitrones derivatives have been started with reduction of nitrobenzene derivatives as starting material bearing electron withdrawing and electron donating groups to corresponding ...
Jihad Haji Mohammed +1 more
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Science Journal of University of Zakho, 2022 Synthetic approached towards the synthesis of some novel nitrones derivatives have been started with reduction of nitrobenzene derivatives as starting material bearing electron withdrawing and electron donating groups to corresponding phenylhydroxylamine
Jihad Haji Mohammed +1 more
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Nitrones as therapeutics [PDF]
Free Radical Biology and Medicine, 2008 Nitrones have the general chemical formula X-CH=NO-Y. They were first used to trap free radicals in chemical systems and then subsequently in biochemical systems. More recently several nitrones, including alpha-phenyl-tert-butylnitrone (PBN), have been shown to have potent biological activity in many experimental animal models.
Robert A, Floyd +5 more
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