Results 21 to 30 of about 13,292 (250)
Molecules, 2013 D-Glucopyranose-derived and L-idopyranose-derived piperidine nitrones were synthesized in good overall yields through six-step reaction sequence starting from readily available 2,3,4,6-tetra-O-benzyl-D-glucopyranose.
Chu-Yi Yu +4 more
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Pharmaceuticals, 2022 In our search for new neuroprotective agents for stroke therapy to improve the pharmacological profile of the compound quinolylnitrone QN23, we have prepared and studied sixteen new, related and easily available quinolylnitrones.
José M. Alonso +4 more
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Results in Chemistry, 2021 Nitrones perform as aldehyde surrogates in the preparation of chalcones via mechanochemical activation under solvent free condition. Aldonitrones containing electron releasing and electron withdrawing substituent on the C-aryl group exhibit differential ...
Jesna Antony +3 more
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Orbital symmetry control in the nitrone-oxaziridine system. Nitrone photostationary states [PDF]
Journal of the American Chemical Society, 1971 Recent the orbital symmetry rules have been shown to apply to hetero-atom systems such as nitrone thermal cycloaddition reactions and the thermal and photochemical aziridine ring cleavage at the C-C bond. The concerted photocyclization is disrotatory and the reverse thermal cleavage is conrotatory in these molecules with four {pi} electrons.
Splitter, Janet S +3 more
openaire +5 more sources
Nitrones: not only extraordinary spin traps, but also good nitric oxide sources in vivo
Acta Pharmaceutica, 2015 Free radicals are involved in the development of reperfusion injuries. Using a spin trap, the intensity of such lesions can be reduced. Nitrones (effective in vivo spin traps) were tried in this work as in vivo nitric oxide donors.
Croitoru Mircea Dumitru +8 more
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Molecules, 2023 [3 + 2] Cycloaddition reactions with the participation of Z-C-(3-pyridyl)-N-methylnitrone and series of E-2-R-nitroethenes were both experimentally and theoretically explored in the framework of Molecular Electron Density Theory.
Jowita Kras +4 more
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Journal of Chemistry, 2015 This paper describes the synthesis of a series of dihydroisoquinoline nitrones by isomerization of the corresponding oxaziridines. Nitrones 4a–c were obtained in excellent yields and high purity by a simple and effective method from the isomerization of ...
Mouna Bouzid +3 more
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Melatonin and Nitrones As Potential Therapeutic Agents for Stroke
Frontiers in Aging Neuroscience, 2016 Stroke is a disease of aging affecting millions of people worldwide, and recombinant tissue-type plasminogen activator (r-tPA) is the only treatment approved.
Alejandro Romero +8 more
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RuO4-mediated oxidation of secondary amines: Part 1. Are hydroxylamines main intermediates? [PDF]
Journal of the Serbian Chemical Society, 2016 The RuO4-catalyzed oxidation of secondary amines Bn-NH-CH2R (1a-b; R=H, Me) gave mainly amides, but minute amounts of nitrones PhCH=N(O)-CH2R (9a-b) and traces of Bn-N(OH)-CH2R (R=H, 4a) were also detected.
Florea Cristina A., Petride Horia
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Molecules, 1998 Enantiomerically pure, five membered cyclic nitrones, easily obtained in large amounts from protected hydroxyacids and aminoacids such as D- and L-tartaric, L-malic, and L-aspartic acids, give cycloaddition reactions with a good diastereocontrol.
Alberto Brandi +4 more
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