Results 21 to 30 of about 7,313 (206)
A new role of N-arylbenzoquinoneimine N-oxides in the von Richter reaction [PDF]
Journal of the Serbian Chemical Society, 2006 The title nitrones react with cyanide ions to give benzoic acids and N-aryl-4-hydroxy-2-cyanophenylamines via two different pathways.
Karami Bahador +3 more
doaj +3 more sources
Amidinoquinoxaline-Based Nitrones as Lipophilic Antioxidants
Antioxidants, 2021 The potential of nitrones (N-oxides) as therapeutic antioxidants is due to their ability to counteract oxidative stress, mainly attributed to their action as radical scavengers toward C- and O-centered radicals.
Nadia Gruber +6 more
doaj +1 more source
Antioxidants, 2021 Synthetic nitrone spin-traps are being explored as therapeutic agents for the treatment of a wide range of oxidative stress-related pathologies, including but not limited to stroke, cancer, cardiovascular, and neurodegenerative diseases. In this context,
Stefania Marano +8 more
doaj +1 more source
Science Journal of University of Zakho, 2023 Synthetic approached towards the synthesis of some novel nitrones derivatives have been started with reduction of nitrobenzene derivatives as starting material bearing electron withdrawing and electron donating groups to corresponding ...
Jihad Haji Mohammed +1 more
doaj +1 more source
Detection of reactive oxygen and nitrogen species by electron paramagnetic resonance (EPR) technique [PDF]
, 2017 During the last decade there has been growing interest in physical-chemical oxidation processes and the behavior of free radicals in living systems. Radicals are known as intermediate species in a variety of biochemical reactions.
Gurer-Orhan, H., Saso, L., Suzen, S.
core +5 more sources
Science Journal of University of Zakho, 2022 Synthetic approached towards the synthesis of some novel nitrones derivatives have been started with reduction of nitrobenzene derivatives as starting material bearing electron withdrawing and electron donating groups to corresponding phenylhydroxylamine
Jihad Haji Mohammed +1 more
doaj +1 more source
Nitrones as therapeutics [PDF]
Free Radical Biology and Medicine, 2008 Nitrones have the general chemical formula X-CH=NO-Y. They were first used to trap free radicals in chemical systems and then subsequently in biochemical systems. More recently several nitrones, including alpha-phenyl-tert-butylnitrone (PBN), have been shown to have potent biological activity in many experimental animal models.
Robert A, Floyd +5 more
openaire +2 more sources
Molecules, 2022 Pyrrolidine nitroxides with four bulky alkyl substituents adjacent to N–O group are known for their high resistance to bioreduction. The 3,4-unsubstituted 2-tert-butyl-2-ethylpyrrolidine-1-oxyls were prepared from the corresponding 2-tert-butyl-1 ...
Andrey I. Taratayko +4 more
doaj +1 more source
Pharmaceuticals, 2022 In our search for new neuroprotective agents for stroke therapy to improve the pharmacological profile of the compound quinolylnitrone QN23, we have prepared and studied sixteen new, related and easily available quinolylnitrones.
José M. Alonso +4 more
doaj +1 more source
Synthesis of nitroxyl radical by direct nucleophilic functionalization of a C-H bond in the azadiene systems [PDF]
, 2012 Cyclic dinitrones underwent nucleophilic substitution of the hydrogen atom in the reaction with a paramagnetic carbanion, the lithium derivative of 4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazol-1-oxyl 3-oxide, to give polyfunctional nitronyl nitroxyls ...
Bogomyakov, A. S. +8 more
core +1 more source