Results 21 to 30 of about 5,274 (162)

Phenotypic and functional characteristics of highly differentiated CD57 +NKG2C + NK cells in HIV-1- infected individuals [PDF]

, 2022
Natural killer (NK) cells are important anti-viral effector cells. The function and phenotype of the NK cells that constitute an individual’s NK cell repertoire can be influenced by ongoing and/or previous viral infections.
Kent, Stephen J., Kent, Helen E, Wragg, Kathleen M, Kelleher, Anthony D, Vanderven, Hillary, Kent, Helen E., Kelleher, Anthony D., Juno, Jennifer A., Grant, Michael D, Vanderven, Hillary A, Juno, Jennifer A, Silvers, Julie, Parsons, Matthew S., Parsons, Matthew S, Kristensen, Anne B., Kristensen, Anne B, Grant, Michael D., Lee, Wen Shi, Kent, Stephen J, Wragg, Kathleen   +19 more
core   +2 more sources

The Interaction of HLA-C1/KIR2DL2/L3 Promoted KIR2DL2/L3 Single-Positive/NKG2C-Positive Natural Killer Cell Reconstitution, Raising the Incidence of aGVHD after Hematopoietic Stem Cell Transplantation

Frontiers in Immunology, 2022
NKG2C+ natural killer (NK) cell plays a vital role in CMV infection control after hematopoietic stem cell transplantation (HSCT). However, the modulation on NKG2C+ NK cell reconstitution is still unclear. NK cell education is affected by the interactions
Wei Zuo, Xing-Xing Yu, Xue-Fei Liu, Ying-Jun Chang, Yu Wang, Xiao-Hui Zhang, Lan-Ping Xu, Kai-Yan Liu, Xiao-Su Zhao, Xiao-Jun Huang, Xiang-Yu Zhao   +10 more
doaj   +1 more source

CXCR6+ and NKG2C+ Natural Killer Cells Are Distinct With Unique Phenotypic and Functional Attributes Following Bone Marrow Transplantation

Frontiers in Immunology, 2022
Reactivation of human cytomegalovirus (HCMV) is a life-threatening complication in transplant patients. Natural Killer (NK) cells are the first lymphocyte lineage to reconstitute following an allogeneic hematopoietic stem cell transplant (HSCT).
Kevin Aviles-Padilla, Laura S. Angelo, Dwight Fan, Dwight Fan, Silke Paust, Silke Paust, Silke Paust   +6 more
doaj   +1 more source

Donor NKG2A/NKG2C Immunophenotype Influences the GMP-Compliant Manufacturing Potential of NK Cells for Adoptive Immunotherapy. [PDF]

Cancers (Basel)
Background: Relapse and opportunistic viral infections remain major causes of treatment failure after allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Meseguer R, Aguilar C, Amat P, Larrea L, Bonora A, Chorão P, Boix F, Piñana JL, Guerrero R, Montesinos P, Vera B, Planelles D, Luis M, Poveda JL, De la Rubia J, Querol S, Arbona C, Guerreiro M, Solano C.   +18 more
europepmc   +2 more sources

Coordination of NK cell markers expression and IgG response in hCMV infection

Медицинская иммунология, 2023
Human cytomegalovirus (hCMV) is a prevalent virus that affects a large proportion of the population worldwide. Natural Killer (NK) cells are essential immune cells that play a crucial role in controlling hCMV infection.
M. O. Ustiuzhanina, Ju. D. Vavilova, N. A. Alekseeva, G. V. Lutcenko, D. M. Chudakov, E. I. Kovalenko   +5 more
doaj   +1 more source

Donor NKG2C homozygosity contributes to CMV clearance after haploidentical transplantation

JCI Insight, 2022
CMV infection remains an important cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Several investigators have reported that adaptive NKG2C+ NK cells persistently expand during CMV reactivation.
Xing-Xing Yu, Qian-Nan Shang, Xue-Fei Liu, Mei He, Xu-Ying Pei, Xiao-Dong Mo, Meng Lv, Ting-Ting Han, Ming-Rui Huo, Xiao-Su Zhao, Ying-Jun Chang, Yu Wang, Xiao-Hui Zhang, Lan-Ping Xu, Kai-Yan Liu, Xiang-Yu Zhao, Xiao-Jun Huang   +16 more
doaj   +1 more source

Significance of HLA-E and its two NKG2 receptors in development of complications after allogeneic transplantation of hematopoietic stem cells

Frontiers in Immunology, 2023
Transplantation of hematopoietic stem cells (HSCT) is a procedure commonly used in treatment of various haematological disorders which is associated with significantly improved survival rates.
Jagoda Siemaszko, Piotr Łacina, Donata Szymczak, Agnieszka Szeremet, Maciej Majcherek, Anna Czyż, Małgorzata Sobczyk-Kruszelnicka, Wojciech Fidyk, Iwona Solarska, Barbara Nasiłowska-Adamska, Patrycja Skowrońska, Maria Bieniaszewska, Agnieszka Tomaszewska, Grzegorz W. Basak, Sebastian Giebel, Tomasz Wróbel, Katarzyna Bogunia-Kubik   +16 more
doaj   +1 more source

Impact of an Immune Modulator Mycobacterium-w on Adaptive Natural Killer Cells and Protection Against COVID-19

Frontiers in Immunology, 2022
The kinetics of NKG2C+ adaptive natural killer (ANK) cells and NKG2A+inhibitory NK (iNK) cells with respect to the incidence of SARS-CoV-2 infection were studied for 6 months in a cohort of healthcare workers following the administration of the heat ...
Sarita Rani Jaiswal, Sarita Rani Jaiswal, Sarita Rani Jaiswal, Jaganath Arunachalam, Ashraf Saifullah, Rohit Lakhchaura, Dhanir Tailor, Anupama Mehta, Gitali Bhagawati, Hemamalini Aiyer, Bakulesh Khamar, Sanjay V. Malhotra, Suparno Chakrabarti, Suparno Chakrabarti   +13 more
doaj   +1 more source

NKG2C+ NK Cells for Immunotherapy of Glioblastoma Multiforme

, 2022
In glioblastoma, non-classical human leucocyte antigen E (HLA-E) and HLA-G are frequently overexpressed. HLA-E loaded with peptides derived from HLA class I and from HLA-G contributes to inhibition of natural killer (NK) cells with expression of the ...
Tonn, Torsten, Murad, Shafiq, Alexander Becker, Becker, Alexander, Shafiq Murad, Achim Temme, Gabriele Schackert, Temme, Achim, Schackert, Gabriele, Füssel, Monika, Frank Momburg, Torsten Tonn, Michen, Susanne, Susanne Michen, Monika Füssel, Momburg, Frank   +15 more
core   +1 more source

Adaptive NKG2C+ NK cells and cytomegalovirus infection in kidney transplant recipients [PDF]

, 2021
Cytomegalovirus (CMV) infection in kidney transplant recipients (KTR) is frequent and may reduce graft and patient survival. T lymphocytes are essential to control the virus, which promotes the adaptive differentiation of NK cells characterized by CD94 ...
Ataya Fernández, Michelle
core   +1 more source