Results 111 to 120 of about 381,426 (191)

Immune regulatory effects of NKG2D ligands

, 2014
Im Kontext des Cancer Immunoediting stellt das NKG2D-Rezeptor-Liganden System eine Möglichkeit zur Unterscheidung zwischen nativen und transformierten Zellen dar.
Häckl, Manuel
core  

Overcoming Target Driven Fratricide for T Cell Therapy

Frontiers in Immunology, 2018
Chimeric Antigen Receptor (CAR) T cells expressing the fusion of the NKG2D protein with CD3ζ (NKG2D-CAR T Cells) acquire a specificity for stress-induced ligands expressed on hematological and solid cancers.
Eytan Breman, Benjamin Demoulin, Sophie Agaugué, Sebastien Mauën, Alexandre Michaux, Lorraine Springuel, Julien Houssa, Fanny Huberty, Céline Jacques-Hespel, Céline Marchand, Jérôme Marijsse, Thuy Nguyen, Nancy Ramelot, Benjamin Violle, Dorothée Daro, Peter De Waele, David E. Gilham, Valérie Steenwinckel   +17 more
doaj   +1 more source

Fusion Proteins of NKG2D/NKG2DL in Cancer Immunotherapy

, 2018
NKG2D (natural killer group 2, member D) is an important activating receptor in natural killer (NK) cells and some T cells. NKG2D ligands (NKG2DLs) are specifically expressed on most tumor cells. The engagement of these ligands on tumor cells to NKG2D on
Yanzhang Wei, Xi Yang, Hui Ding
core   +1 more source

Soluble NKG2D ligands impair CD8⁺ T cell antitumor function dependent of NKG2D downregulation in neuroblastoma. [PDF]

Oncol Lett, 2023
Zhang Y, Luo F, Dong K.
europepmc   +1 more source

The Latest Breakthroughs in Immunotherapy for Acute Myeloid Leukemia, with a Special Focus on NKG2D Ligands. [PDF]

Int J Mol Sci, 2022
Maurer S, Zhong X, Prada BD, Mascarenhas J, de Andrade LF.   +4 more
europepmc   +1 more source

The selenium metabolite methylselenol regulates the expression of ligands that trigger immune activation through the lymphocyte receptor NKG2D

, 2014
For decades Selenium (Se) research has been focused on the identification of active metabolites, which are crucial for Se chemoprevention of cancer.
Hagemann-Jensen, Michael Henrik, Kehlet, Stephanie, Skov, Søren, Gammelgaard, Bente, Ellgaard, Lars, Uhlenbrock, Franziska Katharina, Andresen, Lars, Gabel-Jensen, Charlotte   +7 more
core   +1 more source

β-catenin attenuation leads to up-regulation of activating NKG2D ligands and tumor regression in Braf^V600E-driven thyroid cancer cells. [PDF]

Front Immunol, 2023
Zou M, Al-Yahya S, Al-Alwan M, BinEssa HA, Khabar KSA, Almohanna F, Assiri AM, Altaweel A, Qattan A, Meyer BF, Alzahrani AS, Shi Y.   +11 more
europepmc   +1 more source

Levels of Soluble NKG2D Ligands and Cancer History in Patients Starting Hemodialysis. [PDF]

Front Nephrol, 2022
Nagai K, Tawara T, Usui J, Ebihara I, Ishizu T, Kobayashi M, Maeda Y, Kobayashi H, Yamagata K.   +8 more
europepmc   +1 more source

Inhibition of miR-20a by pterostilbene facilitates prostate cancer cells killed by NK cells via up-regulation of NKG2D ligands and TGF-β1down-regulation. [PDF]

Heliyon, 2023
Youlin K, Simin L, Jian K, Li Z.
europepmc   +1 more source

Stem cell-assisted enzyme/prodrug therapy makes drug-resistant ovarian cancer cells vulnerable to natural killer cells through upregulation of NKG2D ligands. [PDF]

Med Oncol, 2023
Li G, Nikkhoi SK, Hatefi A.
europepmc   +1 more source