Results 151 to 160 of about 381,426 (191)
Effectiveness of NKG2D CAR-NK92 cells in targeting solid tumors: novel dynamic cytotoxicity analysis via real-time cell analysis. [PDF]
Cancer Immunol ImmunotherWang X +6 more
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MicroRNAs and polymorphisms influencing MICA immune modulation. [PDF]
Mol Biol RepNicoletti MB +4 more
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MICA Allelic Variation Modulates Secretion and Protein Flexibility, Impacting on NKG2D-Mediated Immune Responses and Antibody Detection. [PDF]
Eur J ImmunolLópez-Borrego S +5 more
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Challenges and Opportunities of γδ T Cell-Based Immunotherapy for Glioblastoma. [PDF]
BiomedicinesChao CC +5 more
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The Role and Regulation of the NKG2D/NKG2D Ligand System in Cancer [PDF]
Biology, 2023 The family of human NKG2D ligands (NKG2DL) consists of eight stress-induced molecules. Over 80% of human cancers express these ligands on the surface of tumour cells and/or associated stromal elements. In mice, NKG2D deficiency increases susceptibility to some types of cancer, implicating this system in immune surveillance for malignancy.
Katelyn M Spillane, John Maher
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International Journal of Biochemistry and Cell Biology, 2009
NKG2D is an activating immunoreceptor, first recognized on NK cells but subsequently found on gammadelta T cells, CD8(+) alphabeta T cells and macrophages. In NK cells, inhibitory signals are generally dominate over activating signals. However, activating signals mediated through engagement of NKG2D by its ligands on target cells can bypass signals ...
Peyman Obeidy, Alexandra F Sharland
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NKG2D is an activating immunoreceptor, first recognized on NK cells but subsequently found on gammadelta T cells, CD8(+) alphabeta T cells and macrophages. In NK cells, inhibitory signals are generally dominate over activating signals. However, activating signals mediated through engagement of NKG2D by its ligands on target cells can bypass signals ...
Peyman Obeidy, Alexandra F Sharland
exaly +3 more sources
Regulation of NKG2D Stress Ligands and Its Relevance in Cancer Progression
Cancers, 2022 SIMPLE SUMMARY: Immune surveillance during periods of cellular stress is necessary to maintain homeostasis. In distressed cells, the expression of stress (natural killer group 2 member D (NKG2D)) ligands is induced on cells to promote recognition by ...
Lawrence S Lamb +2 more
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Expressions of natural cytotoxicity receptor, NKG2D and NKG2D ligands in endometriosis
Journal of Reproductive Immunology, 2019 Pathogenesis of endometriosis is still unknown, and the relationship between NK cell activating receptors and endometriosis remains to be explored. We investigated the expression of NCRs and NKG2D in NK cells in peripheral blood (PB) and peritoneal fluid (PF) as well as expression of NKG2D ligands in endometrial cells, and illuminated their ...
Hong Xu
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