Results 131 to 140 of about 26,384,108 (210)

Tmem30a protects against podocyte injury through suppression of pyroptosis

iScience
Summary: Podocytopathies, such as focal segmental glomerulosclerosis (FSGS), are characterized by podocyte injury and can easily progress to end-stage kidney disease. However, the mechanisms underlying podocyte injury remain unclear. We observed podocyte
Yanpei Hou, Sipei Chen, Lei Peng, Liming Huang, Huijian Zhang, Ping Zhang, Min Yu, Lin Xiong, Xiang Zhong, Wenjing Liu, Xianjun Zhu, Li Wang, Yi Li, Guisen Li   +13 more
doaj   +1 more source

Structural and Functional Analysis of the NLRP4 Pyrin Domain

, 2012
NLRP4 is a member of the nucleotide binding and leucine rich repeat receptor NLR family of cytosolic receptors and a member of an inflammation signaling cascade.
Wenger, J., Grigoriu, Simina, Diederichs, K., Proell, Martina, Eibl, Clarissa, Hessenberger, M., Wagner, Roland N., Eibl, C., Peti, Wolfgang, Puehringer, Sandra, Diederichs, Kay, Reed, J.C., Peti, W., Pinheiro, A.S., Grigoriu, S., Wagner, R.N., Puehringer, S., Wenger, Julia, Proell, M., Pinheiro, Anderson S., Page, Rebecca, Page, R., Reed, John C., Hessenberger, Manuel   +23 more
core   +1 more source

Directed evolution and structural analysis of an OB-fold domain towards a specifc binding reagent [PDF]

, 2011
Interactions between proteins are a central concept in biology, and understanding and manipulation of these interactions is key to advancing biological science.
Steemson, John Durand
core  

Inter-relationships of galectin-3 and NLR family pyrin domain containing 3 inflammasomes with oral lichen planus: a preliminary cross-sectional in vitro study

BMC Oral Health
Background The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin domain-containing 3 (NLRP3) inflammasome has been reported to be highly expressed in oral lesions with the potential for malignant development such as oral ...
Siting Chen, Xiaoheng Xu, Yang Liu, Yanmei Yao, Yinshen Yang, Wenxia Meng   +5 more
doaj   +1 more source

NLRP3 activation induces BBB disruption and neutrophil infiltration via CXCR2 signaling in the mouse brain

Journal of Neuroinflammation
NLRP3 is an intracellular sensor molecule that affects neutrophil functionality and infiltration in brain disorders such as experimental autoimmune encephalomyelitis (EAE).
Jaeho Lee, Wooyoung Cho, Je-Wook Yu, Young-Min Hyun   +3 more
doaj   +1 more source

Peripheral NLR family pyrin domain-containing 3 protein pathway participates in the development of orofacial inflammatory pain in rats

Oral Biology Research
Myung-Dong Kim, Yu-Mi Kim, Jo-Young Son, Jin-Sook Ju, Dong-Kuk Ahn   +4 more
openaire   +1 more source

Expression of the NLRP12/NF-κB/iNOS axis in lung tissues across stages of non-small cell lung cancer and its mechanism in mediating immune cell regulation. [PDF]

Transl Cancer Res
Xue M, Shi M, Chen J, Wu X.
europepmc   +1 more source

Histone acetylation-regulated FBXO11-dependent degradation of BLIMP-1 promotes lung injury. [PDF]

Transl Pediatr
Sui B, Wang Y, Liu J.
europepmc   +1 more source

Linking deubiquitination to pyroptosis: new perspectives from OTUB1 in hepatocellular carcinoma. [PDF]

J Gastrointest Oncol
Chen L, Wang J, Inuzuka H, Wei W.
europepmc   +1 more source

Isolation of the YB strain of canine distemper virus from Yanbian, China: analysis of JAK2-STAT3 signaling and NLRP3 inflammasome activation in infected cells. [PDF]

J Vet Med Sci
Cao S, Ma H, Hao J, Ji X, Yu K, Zhang X, Zhang S, Sun Z, Zhao J, Xie J, Yu H, Jin J, Gao X.   +12 more
europepmc   +1 more source