Results 141 to 150 of about 22,554 (186)

TH5487 specifically targets NLRP3 in FCAS patients resistant to MCC950. [PDF]

Commun Biol
Lackner A, Picucci SI, Jiang W, Onyuru J, Campos M, Cabral JE, Leonidas L, Macapagal A, Lee H, Henriquez V, Wang K, Xu H, Qiu Y, Albrecht LV, Hoffman HM, McNulty R.   +15 more
europepmc   +1 more source

Puerarin attenuates myocardial ischemia‑reperfusion injury by inhibiting myocardium pyroptosis via the NRF2/HO‑1 signaling pathway. [PDF]

Mol Med Rep
Zheng X, Li J, Hu T, Tan L, Lan D, Deng Y.   +5 more
europepmc   +1 more source

Peroxiredoxin 1, pyroptosis, and the emerging frontier in colorectal cancer therapy. [PDF]

World J Gastroenterol
Maurya DK.
europepmc   +1 more source

The Role of Pyroptosis in Colorectal Cancer: From Mechanisms to Therapeutic Opportunities. [PDF]

Cancer Manag Res
Xie H, Deng X, Li Q.
europepmc   +1 more source

Exploring the protective mechanisms and therapeutic potential of carnosic acid against acute respiratory distress syndrome through molecular docking, molecular dynamics and experimental verification. [PDF]

Exp Ther Med
Li Q, Ding L, Sun H, Ding W, Wang M, Sun Z, Ma C.   +6 more
europepmc   +1 more source

Advances in cellular and molecular mechanisms of trauma-induced organ inflammation and dysfunction. [PDF]

Burns Trauma
Wang J, Liang H, Fan J.
europepmc   +1 more source

An integrative computational approach for identification of NLRP3 inhibitors through machine learning, docking, dynamics and DFT analysis. [PDF]

Sci Rep
Alzarea SI.
europepmc   +1 more source

Gastrointestinal microbiota and inflammasomes interplay in health and disease: a gut feeling. [PDF]

Gut
De Luca R, Arrè V, Nardone S, Incerpi S, Giannelli G, Trivedi P, Anastasiadou E, Negro R.   +7 more
europepmc   +1 more source

Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis. [PDF]

Int J Mol Med
Sun W, Liao Y, Feng J, Liang J, He Q, Cui Y, Huang D, Shi H, You W, Sun W, Yi Q.   +10 more
europepmc   +1 more source