Results 11 to 20 of about 10,792,655 (300)
HLA and non-HLA polymorphisms in renal transplantation
Swiss Medical Weekly, 2012 Despite progress made in the field of immunosuppression, graft rejection remains a major cause of morbidity and mortality of patients after solid organ transplantation.
Stéphanie Laperrousaz +3 more
doaj +5 more sources
Pathobiology of Non-HLA immunity in renal transplantation
Indian Journal of Transplantation, 2021 Conventionally, major histocompatibility complex (MHC)-encoded human leukocyte antigens (HLAs) of a donor are considered as the principal targets of the recipient's immune system in renal transplantation (RT), and the clinical significance of anti-HLA ...
Praveen Kumar Etta +2 more
doaj +2 more sources
Probir antitijela non-HLA – prvi rezultati
Liječnički vjesnikCilj: Važnost i uloga antitijela usmjerenih protiv humanih leukocitnih antigena (HLA) u reakcijama odbacivanja posredovanih antitijelima nakon transplantacije solidnih organa danas je jasno dokazana.
Marija Burek Kamenarić +2 more
doaj +3 more sources
The importance of non-HLA antibodies in transplantation [PDF]
Nature Reviews Nephrology, 2016 The development of post-transplantation antibodies against non-HLA autoantigens is associated with rejection and decreased long-term graft survival. Although our knowledge of non-HLA antibodies is incomplete, compelling experimental and clinical findings demonstrate that antibodies directed against autoantigens such as angiotensin type 1 receptor ...
Zhang, Qiuheng, Reed, Elaine F
openaire +4 more sources
Frontiers in Immunology, 2022 BackgroundMany kidney allografts fail due to the occurrence of antibody-mediated rejection (ABMR), related to donor-specific anti-HLA antibodies (HLA-DSA). However, the histology of ABMR can also be observed in patients without HLA-DSA.
Aleksandar Senev +13 more
doaj +1 more source
Editorial: A hill of needs: Non-HLA antibodies and transplantation. [PDF]
Front Immunol, 2022 Otten HG, Dieudé M, Hickey MJ.
europepmc +4 more sources
Integrated analysis reveals prognostic value of HLA-I LOH in triple-negative breast cancer
Journal for ImmunoTherapy of Cancer, 2021 Background Triple-negative breast cancers (TNBCs), especially those non-immune-inflamed tumors, have a poor prognosis and limited therapies. Human leukocyte antigen (HLA)-I not only contributes to antitumor immune response and the phenotype of the tumor ...
Yi Xiao +5 more
doaj +1 more source
Frontiers in Immunology, 2021 BackgroundCorrelation between antibody-mediated rejection (ABMR) and circulating HLA donor-specific antibodies (HLA-DSA) is strong but imperfect in kidney transplant (KT) recipients, raising the possibility of undetected HLA-DSA or non-HLA antibodies ...
Marta Crespo +27 more
doaj +1 more source
Symposium 6: HLA and Non-HLA genetic predisposition
Revista de la Sociedad Argentina de Diabetes, 2020 Symposium 6: Autoimmune diabetes: heterogeneity in its clinical presentations HLA and Non-HLA genetic predisposition Type 1 diabetes is a multifactorial autoimmune disease.
Gloria Cerrone
doaj +1 more source
PTPN22: the archetypal non-HLA autoimmunity gene [PDF]
Nature Reviews Rheumatology, 2014 PTPN22 encodes a tyrosine phosphatase that is expressed by haematopoietic cells and functions as a key regulator of immune homeostasis by inhibiting T-cell receptor signalling and by selectively promoting type I interferon responses after activation of myeloid-cell pattern-recognition receptors.
Stephanie M, Stanford, Nunzio, Bottini
openaire +2 more sources