Results 21 to 30 of about 2,154 (127)
Morning clock gene expression in young adults of early and late chronotypes [PDF]
Scientific ReportsVariations in circadian rhythm-related genes influence the individual chronotype. Here, we hypothesize that the peak of clock gene expression at 7 a.m.
Bettina Krueger +5 more
doaj +2 more sources
Biomedical JournalBackground: Micro-ribonucleic acids (miRNAs) are involved in osteoarthritis (OA) pathogenesis and clock-controlled genes (CCGs) regulation. However, the interaction between miRNAs and CCGs remains unclear.
Jih-Yang Ko +2 more
exaly +3 more sources
The Impact of Deep Brain Stimulation of the Subthalamic Nucleus on Sleep-Wake Function and Circadian Rhythms in Patients with Parkinson's Disease. [PDF]
Mov Disord Clin PractAbstract Background Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a well‐established therapy in advanced Parkinson's disease (PD) improving motor and non‐motor signs including sleep. The mechanisms of sleep improvement are insufficiently understood.
Steinhardt J +6 more
europepmc +2 more sources
Nuclear receptor subfamily 1 group D member 1 (NR1D1; Rev-ERBAα); NR1D2 (Rev-ERBAβ) [PDF]
Science-Business EXchange, 2012 exaly +2 more sources
BMJ Open Respiratory Research, 2022 Introduction Cellular circadian rhythms regulate immune pathways and inflammatory responses that mediate human disease such as asthma. Circadian rhythms in the lung may also contribute to exacerbations of chronic diseases such as asthma by regulating ...
Weston T Powell +4 more
doaj +1 more source
Agomelatine, a Melatonin-Derived Drug, as a New Strategy for the Treatment of Colorectal Cancer
Antioxidants, 2023 The potential use of agomelatine as an alternative treatment for colorectal cancer is evaluated in this work. The effect of agomelatine was studied in an in vitro model using two cell lines with different p53 statuses (HCT-116, wild-type p53, and HCT-116
Sara Moreno-SanJuan +7 more
doaj +1 more source
Control of gene expression by the retinoic acid-related orphan receptor alpha in HepG2 human hepatoma cells. [PDF]
PLoS ONE, 2011 Retinoic acid-related Orphan Receptor alpha (RORα; NR1F1) is a widely distributed nuclear receptor involved in several (patho)physiological functions including lipid metabolism, inflammation, angiogenesis, and circadian rhythm.
Caroline Chauvet +7 more
doaj +1 more source
Core Circadian Clock Proteins as Biomarkers of Progression in Colorectal Cancer
Biomedicines, 2021 Colorectal cancer (CRC) is one of the most common tumours in developed countries. Although its incidence and mortality rates have decreased, its prognosis has not changed, and a high percentage of patients with CRC develop relapse (metachronous ...
María I. Aroca-Siendones +9 more
doaj +1 more source
Frontiers in Marine Science, 2022 Pearl gentian grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂) is a hybrid fish with high commercial value. It is widely cultured on the Asian coast; however, it is not cold-tolerant.
Ben-Ben Miao +6 more
doaj +1 more source
Co-alterations of circadian clock gene transcripts in human placenta in preeclampsia
Scientific Reports, 2022 Pre-eclampsia (PE) is a hypertensive condition that occurs during pregnancy and complicates up to 4% of pregnancies. PE exhibits several circadian-related characteristics, and the placenta possesses a functioning molecular clock.
Guoli Zhou +5 more
doaj +1 more source