Results 61 to 70 of about 179,291 (216)

Broccoli or Sulforaphane: Is It the Source or Dose That Matters?

Molecules, 2019
There is robust epidemiological evidence for the beneficial effects of broccoli consumption on health, many of them clearly mediated by the isothiocyanate sulforaphane.
Yoko Yagishita, Jed W. Fahey, Albena T. Dinkova-Kostova, Thomas W. Kensler   +3 more
doaj   +1 more source

Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction [PDF]

, 2010
Abnormal lung inflammation and oxidant burden are associated with a significant reduction in histone deacetylase 2 (HDAC2) abundance and steroid resistance.
Adenuga, Adenuga, Barnes, David Adenuga, Garbin, Goven, Harju, Hew, Hongwei Yao, Irfan Rahman, Isaac K. Sundar, Ito, Ito, Itoh, Jae-Woong Hwang, Jaiswal, Keatings, Kramer, Liu, Malhotra, Marwick, Rahman, Rangasamy, Samuel Caito, Sangwoon Chung, Southam, Sun, Tomaki, Trivedi, Yang, Yang, Yao, Yao, Zimmermann   +33 more
core   +1 more source

Features of the free radical status of the follicular fluid of mares in the process of folliculogenesis

Siberian Journal of Life Sciences and Agriculture
Background.  The maturation of germ cells is a complex and multilevel process. To increase the effectiveness of assisted reproductive technologies in horses, a detailed study of the mechanisms of regulation of folliculogenesis is necessary. Purpose. A
Valery V. Kalashnikov, Lyudmila F. Lebedeva, Olga V. Bakovetskaya, Anna A. Terekhina, Elena V. Solodova, Yulia V. Abalenikhina, Aleksey V. Shchulkin   +6 more
doaj   +1 more source

VA inhibits LPS-induced oxidative stress via modulating Nrf2/NF-κB-signalling pathways in bovine mammary epithelial cells

Italian Journal of Animal Science, 2019
The current study was conducted to examine the pre-protection effects of vitamin A (VA) on lipopolysaccharide (LPS)-induced oxidative damage in bovine mammary epithelial cells (BMECs) and to explore the antioxidant mechanisms of VA via nuclear factor ...
Huiyu Shi, Xiaoyu Guo, Sumei Yan, Yongmei Guo, Binlin Shi, Yanli Zhao   +5 more
doaj   +1 more source

Nrf2 signaling and cell survival [PDF]

Toxicology and Applied Pharmacology, 2010
Nrf2:INrf2 acts as a sensor for oxidative/electrophilic stress. INrf2 serves as an adaptor to link Nrf2 to the ubiquitin ligase Cul3-Rbx1 complex that ubiquitinate and degrade Nrf2. Under basal conditions, cytosolic INrf2/Cul3-Rbx1 is constantly degrading Nrf2.
Suryakant K, Niture, James W, Kaspar, Jun, Shen, Anil K, Jaiswal   +3 more
openaire   +2 more sources

Elucidating the Role of Nrf2 Signaling Pathway in Mycoplasma Infections

Frontiers in Bioscience-Landmark
Mycoplasmas are the smallest cell-wall-less self-replicating prokaryotes. Mycoplasma species can be found within and outside cells as “silent parasites” that live intracellularly and as membrane surface parasites.
Sarmistha Saha, Nadezhda Sachivkina, Olga Kuznetsova, Ekaterina Neborak, Natallia Zhabo   +4 more
doaj   +1 more source

Spongionella secondary metabolites protect mitochondrial function in cortical neurons against oxidative stress [PDF]

, 2014
Accepted: 8 January 2014 This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Acknowledgments
Alfonso, Amparo, Alonso, Eva, Botana, Luis M, Ebel, Rainer, Houssen, Wael E, Jaspars, Marcel, Leirós, Marta, Rateb, Mostafa E, Rateb, Mostafa Ezzat Mohamed, Sánchez, Jon A   +9 more
core   +4 more sources

1,3,4, Oxadiazole Compound A3 Provides Robust Protection Against PTZ-Induced Neuroinflammation and Oxidative Stress by Regulating Nrf2-Pathway [Retraction]

Journal of Inflammation Research, 2022
Alvi AM, Shah FA, Muhammad AJ, Feng J, Li S. J Inflamm Res. 2021;14:7393–7409. The Editor and Publisher of Journal of Inflammation Research wish to retract the published article.
Alvi AM, Shah FA, Muhammad AJ, Feng J, Li S   +4 more
doaj  

Is a Meal without Wine Good for Health?

Diseases, 2018
Hippocrates, the father of medicine, had said: “Wine is a thing wonderfully appropriate to man if, in health as in disease, it is administered with appropriate and just measure according to the individual constitution.„ Wine has always ...
Jean-Pierre Rifler
doaj   +1 more source

Fibroblasts derived from long-lived insulin receptor substrate 1 null mice are not resistant to multiple forms of stress [PDF]

, 2014
Reduced signalling through the insulin/insulin-like growth factor-1 signalling (IIS) pathway is a highly conserved lifespan determinant in model organisms.
Page, Melissa M., Robb, Ellen L., Selman, Colin, Sinclair, Amy, Stuart, Jeffrey A., Withers, Dominic J.   +5 more
core   +1 more source