Results 261 to 270 of about 112,785 (303)

Research Progress of Nrf2 Signaling Pathway on Diabetic Nephropathy

2018 International Conference on Medicine, Biology, Materials and Manufacturing (ICMBMM 2018), 2018
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The role of the KEAP1-NRF2 signaling pathway in form deprivation myopia guinea pigs. [PDF]

BMC Ophthalmol
Gu Z, Meng J, Zhong W, Lan C, Tan Q, Xiang X, Zhou H, Liao X.   +7 more
europepmc   +1 more source

Dihydroartemisinin ameliorates hemarthrosis-induced cartilage degeneration by suppressing chondrocyte senescence via activation of Keap1-Nrf2 signaling pathway. [PDF]

J Orthop Translat
Zeng Q, Feng Y, Huang H, Zou K, Chen W, Li X, Huang Y, Wang W, Yuan W, Wang P, Tong P, Jin H, Chen J.   +12 more
europepmc   +1 more source

Dietary Zinc activates the Nrf2 signaling pathway to inhibit pyroptosis and attenuate the lung inflammatory response in COPD. [PDF]

Cytotechnology
Huang Y, Liang T, Liu J, Yu H, Li J, Han L.   +5 more
europepmc   +1 more source

Editorial: Modulation of oxidative stress and inflammation via the NRF2 signaling pathway. [PDF]

Front Pharmacol
Saha S, Buttari B, Saso L.
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Mechanistic Studies of the Nrf2-Keap1 Signaling Pathway

Drug Metabolism Reviews, 2006
Since eukaryotic cells constantly encounter various environmental insults, they have evolved defense mechanisms to cope with toxicant- and carcinogen-induced oxidative stress or electrophiles. One of the most important cellular defense mechanisms against oxidative stress or electrophiles is mediated by the transcription factor Nrf2.
Donna D Zhang
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The Nrf2-Keap1/ARE signaling pathway in aquatic animals

International Journal of Biological Macromolecules
The complex and fluctuating conditions of aquatic ecosystems make aquatic organisms vulnerable to oxidative stress. The Nrf2-Keap1/ARE signaling pathway serves as an important intracellular defense mechanism, particularly for aquatic organisms exposed to environmental stressors and toxic substances.
Dan-Dan, Bian, Xue, Zhang, Xi-Rong, Zhu, Wen-Hui, Tang, Qin, Peng, Yao-Hui, Chen, Gang, Wang, Dai-Zhen, Zhang, Bo-Ping, Tang, Qiu-Ning, Liu   +9 more
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Cardioprotective Effects of Natural Products via the Nrf2 Signaling Pathway

Current Vascular Pharmacology, 2021
Due to its poor regenerative capacity, the heart is specifically vulnerable to xenobiotic- induced cardiotoxicity, myocardial ischaemia/reperfusion injury and other pathologies. Nuclear factor erythroid-2-related factor 2 (Nrf2) is considered as an essential factor in protecting cardiomyocytes against oxidative stress resulting from free radicals and
Rasool, Tavakoli, Jamshid, Tabeshpour, Javad, Asili, Abolfazl, Shakeri, Amirhossein, Sahebkar   +4 more
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Targeting Keap1/Nrf2/ARE signaling pathway in multiple sclerosis

European Journal of Pharmacology, 2020
Multiple sclerosis (MS) is a neurologic autoimmune disorder featured by chronic inflammation of the central nervous system, demyelination and axonal damage. Recently, the term "oxinflammation" has been proposed to depict the vicious circle of chronic inflammation and oxidative stress (OS).
Danica, Michaličková, Tomáš, Hrnčíř, Nikolina Kutinová, Canová, Ondřej, Slanař   +3 more
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Keap1‐Nrf2 signaling pathway in angiogenesis and vascular diseases

Journal of Tissue Engineering and Regenerative Medicine, 2020
The transcription factor, nuclear factor E2-related factor 2 (Nrf2), is highly sensitive to oxidative burst products, including reactive oxygen species (ROS) and reactive nitrogen species. In the cell nucleus, Nrf2 activates various antioxidant genes by binding to the antioxidant response elements.
Zi Guo, Zhaohui Mo
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