Results 191 to 200 of about 29,671 (305)

Full solid-state magnetic refrigeration device toward thermal management. [PDF]

Proc Natl Acad Sci U S A
Lin Y, Franco V, Wang J, Law JY, Chen Y, Sun J, Zhao T, Hu F, Shen B.   +8 more
europepmc   +1 more source

Global Regulation of Time-Delay Cascade Systems via Partial State Feedback**This work was supported in part by Key Project of NSFC under Grant 61533009, 61273141 and 2014CB046406, 111 Project (B08015), Research Projects (KQC201105300002A), (JCY201303291521257) and (JCYJ20150403161923519).

IFAC-PapersOnLine, 2016
Xu Zhang, Wei Lin, Yan Lin
openaire   +1 more source

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

Advanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang, Chunhua Ren, Zhou Qin, Yimeng Cui, Bingbing Zhang, Peng Luo, Xuan Wang, Yaoqi Xie, Xin Zhang, Aifen Yan, Yang Zhang, Dingding Fan, Yang Liu, Wenjie Pan, Xiao Jiang, Lihong Yuan, Haipeng Qin, David M. Irwin, Chaoqun Hu, Yang Liu, Ting Chen   +20 more
wiley   +1 more source

Covalent FAPI Imaging-Guided Precision Surgery in Patients with Medullary Thyroid Carcinoma: A Phase II Clinical Trial. [PDF]

Clin Cancer Res
Kong Z, Liu Y, Lin YS, Li Z, Cui XY, Liu S, Zhang X, Li R, Yang Y, Sun Y, Nie Y, Zhang Z, An C, Ni S, Zhu Y, Liu Z, Wang J, Liu S.   +17 more
europepmc   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

Advanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng   +7 more
wiley   +1 more source

Quantum interference of single photons without optical superposition: Toward high resolution imaging in spatial and spectral domains. [PDF]

Sci Adv
Zhang Y, Cui L, Guo X, Kang G, Zhao W, Deng Q, Tang X, Li X, Li C, Ou ZY.   +9 more
europepmc   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

Weakly Anisotropic Superconductivity of Pr₄Ni₃O₁₀ Single Crystals. [PDF]

J Am Chem Soc
Pei C, Shen Y, Peng D, Zhang M, Zhao Y, Xing X, Wang Q, Wu J, Wang J, Zhao L, Xing Z, Chen Y, Zhao J, Yang W, Liu X, Shi Z, Guo H, Zeng Q, Zhang GM, Qi Y.   +19 more
europepmc   +1 more source

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

Advanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu, Bingwei Wang, Zhijie Su, Xiaoxv Han, Miao He, Yun Zhao, Yujia Hou, Daotong Li, Weiguang Zhang, Lihua Qin, Ke Wang, Yanchun Li, Yi Yan, Siwang Yu, Xiaoshuai Huang, Tairan Yuwen, Jianyuan Luo, Ruimao Zheng   +17 more
wiley   +1 more source

Correction: Editorial: New advancement in tumor microenvironment remodeling and cancer therapy, volume II. [PDF]

Front Cell Dev Biol
Qin S, Xiao X, Shen Y, Pei Z, Zuo X, Yao Y.   +5 more
europepmc   +1 more source