Results 61 to 70 of about 15,740 (146)

Functional networks of nucleocytoplasmic transport-related genes differentiate ischemic and dilated cardiomyopathies. A new therapeutic opportunity.

, 2014
Heart failure provokes alterations in the expression of nucleocytoplasmic transport-related genes. To elucidate the nucleocytoplasmic transport-linked functional network underlying the two major causes of heart failure, ischemic cardiomyopathy (ICM) and ...
Luis Martínez-Dolz (331425), Miguel Rivera (299169), Manuel Portolés (299177), Miguel Rivera, Francisca Lago (293475), Francisca Lago, Jose Ramón González-Juanatey (5660251), María Micaela Molina-Navarro (5660248), Luis Martínez-Dolz, María Micaela Molina-Navarro, Juan Carlos Triviño (531122), Juan Carlos Triviño, Manuel Portolés, Jose Ramón González-Juanatey   +13 more
core   +1 more source

Role of molecular charge in nucleocytoplasmic transport.

, 2014
Transport of genetic materials and proteins between the nucleus and cytoplasm of eukaryotic cells is mediated by nuclear pore complexes (NPCs). A selective barrier formed by phenylalanine-glycine (FG) nucleoporins (Nups) with net positive charges in the ...
Goryaynov Alexander, Yang Weidong, Weidong Yang, Alexander Goryaynov (524216), Alexander Goryaynov, Weidong Yang (162872)   +5 more
core   +1 more source

A Pharmacological Approach to Identify Small Molecules Capable of Rescuing Nucleocytoplasmic Transport and DNA Damage Phenotypes in C9ORF72 ALS/FTD

, 2022
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease with available treatments only marginally slowing progression or improving survival.
Ramic, Melina
core  

Nuclear pore complex and nucleocytoplasmic transport disruption in neurodegeneration. [PDF]

FEBS Lett, 2023
Cristi AC, Rapuri S, Coyne AN.
europepmc   +1 more source

Exportin-mediated nucleocytoplasmic transport maintains Pch2 homeostasis during meiosis. [PDF]

PLoS Genet, 2023
Herruzo E, Sánchez-Díaz E, González-Arranz S, Santos B, Carballo JA, San-Segundo PA.   +5 more
europepmc   +1 more source

Fifty years of nuclear pores and nucleocytoplasmic transport studies: multiple tools revealing complex rules.

, 2014
International audienceNuclear pore complexes (NPCs) are multiprotein assemblies embedded within the nuclear envelope and involved in the control of the bidirectional transport of proteins and ribonucleoparticles between the nucleus and the cytoplasm ...
Palancade, Benoit, Doye, Valérie, Benoit Palancade, Valérie Doye, Aurélie G. Floch, Floch, Aurélie G   +5 more
core   +1 more source

Evolutionary, structural and functional insights in nuclear organisation and nucleocytoplasmic transport in trypanosomes. [PDF]

FEBS Lett, 2023
Padilla-Mejia NE, Field MC.
europepmc   +1 more source

Unraveling the impact of disrupted nucleocytoplasmic transport systems in C9orf72-associated ALS. [PDF]

Front Cell Neurosci, 2023
McGoldrick P, Robertson J.
europepmc   +1 more source

Experience-dependent Tip60 nucleocytoplasmic transport is regulated by its NLS/NES sequences for neuroplasticity gene control. [PDF]

Mol Cell Neurosci, 2023
Armour EM, Thomas CM, Greco G, Bhatnagar A, Elefant F.   +4 more
europepmc   +1 more source

Nucleocytoplasmic transport of active HER2 causes fractional escape from the DCIS-like state. [PDF]

Nat Commun, 2023
Wang L, Paudel BB, McKnight RA, Janes KA.   +3 more
europepmc   +1 more source