Results 41 to 50 of about 10,026 (221)
Frontiers in Plant Science, 2014 Mutations in the Lotus japonicus nucleoporin genes, NUP85, NUP133 and NENA (SEH1), lead to defects in plant-microbe symbiotic signaling. The homologous proteins in yeast and vertebrates are part of the conserved NUP84/NUP107-160 sub-complex, which is an ...
Andreas eBinder, Martin eParniske
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The Human NUP58 Nucleoporin Can Form Amyloids In Vitro and In Vivo
Biomedicines, 2021 Amyloids are fibrillar protein aggregates with a cross-β structure and unusual features, including high resistance to detergent or protease treatment.
Lavrentii G. Danilov +6 more
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Proteomic Analysis of Nucleoporin Interacting Proteins [PDF]
Journal of Biological Chemistry, 2001 The Saccharomyces cerevisiae nuclear pore complex is a supramolecular assembly of 30 nucleoporins that cooperatively facilitate nucleocytoplasmic transport. Thirteen nucleoporins that contain FG peptide repeats (FG Nups) are proposed to function as stepping stones in karyopherin-mediated transport pathways.
N P, Allen +3 more
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Exotic mitotic mechanisms [PDF]
, 2012 The emergence of eukaryotes around two billion years ago provided new challenges for the chromosome segregation machineries: the physical separation of multiple large and linear chromosomes from the microtubule-organizing centres by the nuclear envelope.
Drechsler, Hauke, McAinsh, Andrew D.
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Complex Commingling: Nucleoporins and the Spindle Assembly Checkpoint
Cells, 2015 The segregation of the chromosomes during mitosis is an important process, in which the replicated DNA content is properly allocated into two daughter cells.
Ikram Mossaid, Birthe Fahrenkrog
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Small and large intestine express a truncated Dab1 isoform that assembles in cell-cell junctions and co-localizes with proteins involved in endocytosis [PDF]
, 2018 Disabled-1 (Dab1) is an essential intracellular adaptor protein in the reelin pathway. Our previous studies in mice intestine showed that Dab1 transmits the reelin signal to cytosolic signalling pathways.
Balda, María S. +5 more
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Viral Subversion of the Nuclear Pore Complex
Viruses, 2013 The nuclear pore complex (NPC) acts as a selective barrier between the nucleus and the cytoplasm and is responsible for mediating communication by regulating the transport of RNA and proteins. Numerous viral pathogens have evolved different mechanisms to
Valerie Le Sage, Andrew J. Mouland
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Three-dimensional structure and flexibility of a membrane-coating module of the nuclear pore complex. [PDF]
, 2009 The nuclear pore complex mediates nucleocytoplasmic transport in all eukaryotes and is among the largest cellular assemblies of proteins, collectively known as nucleoporins. Nucleoporins are organized into distinct subcomplexes.
Blobel, Günter, Kampmann, Martin
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Regulation of autophagy by nucleoporin Tpr [PDF]
Scientific Reports, 2012 The nuclear pore complex (NPC) consists of a conserved set of ~30 different proteins, termed nucleoporins, and serves as a gateway for the exchange of materials between the cytoplasm and nucleus. Tpr (translocated promoter region) is a component of NPC that presumably localizes at intranuclear filaments. Here, we show that Tpr knockdown caused a severe
Funasaka, Tatsuyoshi +2 more
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Nuclear pore complex and stem cell homeostasis
生物医学转化, 2021 As a channel for mediating exchange between the nucleus and cytoplasm, the nuclear pore complex (NPC) is a macromolecular complex composed of about 30 nucleoporins.
Li Lanzhu +4 more
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