Results 61 to 70 of about 6,849 (214)

Nucleoporins: leaving the nuclear pore complex for a successful mitosis.

, 2011
The nuclear envelope (NE) separates the cytoplasm and the cell nucleus of interphase eukaryotic cells and nuclear pore complexes (NPCs) mediate the macromolecular exchange between these two compartments.
Fahrenkrog, Birthe, Chatel, Guillaume, Guillaume Chatel, Birthe Fahrenkrog   +3 more
core   +1 more source

An Arabidopsis Nucleoporin NUP85 modulates plant responses to ABA and salt stress. [PDF]

PLoS Genetics, 2017
Several nucleoporins in the nuclear pore complex (NPC) have been reported to be involved in abiotic stress responses in plants. However, the molecular mechanism of how NPC regulates abiotic stress responses, especially the expression of stress responsive
Yingfang Zhu, Bangshing Wang, Kai Tang, Chuan-Chih Hsu, Shaojun Xie, Hai Du, Yuting Yang, Weiguo Andy Tao, Jian-Kang Zhu   +8 more
doaj   +1 more source

SuperResNET: Model‐Free Single‐Molecule Network Analysis Software Achieves Molecular Resolution of Nup96

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
SuperResNET is a powerful integrated software that reconstructs network architecture and molecular distribution of subcellular structures from single molecule localization microscopy datasets. SuperResNET segments the nuclear pore complex and corners, extracts size, shape, and network features of all segmented nuclear pores and uses modularity analysis
Yahongyang Lydia Li, Ismail M. Khater, Christian Hallgrimson, Ben Cardoen, Timothy H. Wong, Ghassan Hamarneh, Ivan R. Nabi   +6 more
wiley   +1 more source

Prion formation by a yeast GLFG nucleoporin [PDF]

Prion, 2012
The self-assembly of proteins into higher order structures is both central to normal biology and a dominant force in disease. Certain glutamine/asparagine (Q/N)-rich proteins in the budding yeast Saccharomyces cerevisiae assemble into self-replicating amyloid-like protein polymers, or prions, that act as genetic elements in an entirely protein-based ...
Halfmann, Randal Arthur, Wright, Jessica R., Alberti, Simon, Lindquist, Susan, Rexach, Michael   +4 more
openaire   +4 more sources

The nuclear envelope and nuclear pore complexes in neurodegenerative diseases

Frontiers in Cell and Developmental Biology
The nuclear envelope (NE) and nuclear pore complexes (NPCs) play a critical role in maintaining the balance between the nucleus and cytoplasm, which is essential for the structural integrity and gene regulatory functions of eukaryotic cells.
Tingyan Wu, Tingyan Wu, Haochen Xu, Haochen Xu, Lei Cheng, Lei Cheng, Ruoxin Wu, Ruoxin Wu, Fuzheng Guo, Xi Chen, Xi Chen   +10 more
doaj   +1 more source

Ordered Regions of Channel Nucleoporins Nup62, Nup54, and Nup58 Form Dynamic Complexes in Solution [PDF]

, 2015
Three out of ∼30 nucleoporins, Nup62, Nup54, and Nup58, line the nuclear pore channel. These “channel” nucleoporins each contain an ordered region of ∼150–200 residues, which is predicted to be segmented into 3–4 α-helical regions of ∼40–80 residues ...
Melcak, Ivo, Blobel, Guenter, Solmaz, Sozanne R, Sharma, Alok   +3 more
core   +1 more source

Linking Nucleoporins, Mitosis, and Colon Cancer [PDF]

Cell Chemical Biology, 2016
Suppression of a nuclear pore protein Nup358/RanBP2 is linked to mitotic cell death, but the clinical relevance of this link is unknown. In a recent issue of Cell, Vecchione et al. (2016) show that in approximately 10% of BRAF-like colorectal cancer (CC) patients, Nup358/RanBP2 is critical for survival.
Richard W, Wong, Maximiliano, D'Angelo
openaire   +2 more sources

RNA‐Binding Proteins Shape Mammalian Retroelement RNA Fate: Lessons From HIV‐1, LINE‐1, and Related Reverse‐Transcribing Elements

Animal Research and One Health, EarlyView.
RNA‐binding proteins (RBPs) and RNA‐associated factors shape retroelement RNA fate by regulating RNA processing, translation, RNP assembly and remodeling, reverse transcription, nuclear trafficking, chromatin engagement, and RNA surveillance. These pathways balance productive retroviral replication or retrotransposon insertion with RNA decay ...
Mingrui Li, Zhangyuan Pan, Yongjuan Guan
wiley   +1 more source

NUP214 (nucleoporin 214kDa) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on NUP214 (nucleoporin 214kDa), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +1 more source

Proteomic Analysis of Nucleoporin Interacting Proteins [PDF]

Journal of Biological Chemistry, 2001
The Saccharomyces cerevisiae nuclear pore complex is a supramolecular assembly of 30 nucleoporins that cooperatively facilitate nucleocytoplasmic transport. Thirteen nucleoporins that contain FG peptide repeats (FG Nups) are proposed to function as stepping stones in karyopherin-mediated transport pathways.
N P, Allen, L, Huang, A, Burlingame, M, Rexach   +3 more
openaire   +2 more sources