Results 111 to 120 of about 67,898 (346)

Impact of dietary manganese on intestinal barrier and inflammatory response in broilers challenged with Salmonella Typhimurium [PDF]

, 2020
Growing concern for public health and food safety has prompted a special interest in developing nutritional strategies for removing waterborne and foodborne pathogens, including Salmonella.
Bai, Jie, Bai, Shiping, Ding, Xuemei, Michiels, Joris, Pan, Shuqin, Peng, Huanwei, Su, Zhuowei, Wang, Jianping, Xuan, Yue, Zeng, Qiufeng, Zhang, Huaiyong, Zhang, Keying   +11 more
core   +2 more sources

Impaired barrier function in patients with house dust mite-induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression.

Journal of Allergy and Clinical Immunology, 2016
BACKGROUND Tight junction (TJ) defects have recently been associated with asthma and chronic rhinosinusitis. The expression, function, and regulation of nasal epithelial TJs remain unknown in patients with allergic rhinitis (AR).
B. Steelant, R. Farré, P. Wawrzyniak, J. Belmans, E. Dekimpe, H. Vanheel, L. Van Gerven, Inge Kortekaas Krohn, D. Bullens, J. Ceuppens, C. Akdis, G. Boeckxstaens, S. Seys, P. Hellings   +13 more
semanticscholar   +1 more source

Occludin is overexpressed in Alzheimer's disease and vascular dementia [PDF]

Journal of Cellular and Molecular Medicine, 2007
AbstractThe tight junctions (TJs) are key players in the control of blood‐brain barrier (BBB) properties, the most complex TJs in the vascular system being found in the endothelial cells of brain capillaries. One of the main TJs proteins is occludin, which anchors plasma membranes of neighbour cells and is present in large amounts in the brain ...
Romanitan, Mihaela Oana, Popescu, Bogdan O, Winblad, Bengt, Bajenaru, Ovidiu Alexandru, Bogdanovic, Nenad   +4 more
openaire   +2 more sources

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

Advanced Science, EarlyView.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai, Siying Cheng, Fengguang Ma, Xiaorong Zhang, Jianan Huang, Zhonghua Liu, Bing Hu   +6 more
wiley   +1 more source

Protective effect of bile acids on the onset of fructose-induced hepatic steatosis in mice

Journal of Lipid Research, 2010
Fructose intake is being discussed as a key dietary factor in the development of nonalcoholic fatty liver disease (NAFLD). Bile acids have been shown to modulate energy metabolism. We tested the effects of bile acids on fructose-induced hepatic steatosis.
Valentina Volynets, Astrid Spruss, Giridhar Kanuri, Sabine Wagnerberger, Stephan C. Bischoff, Ina Bergheim   +5 more
doaj   +1 more source

Polarised epithelial monolayers of the gastric mucosa reveal insights into mucosal homeostasis and defence against infection [PDF]

, 2018
Objective Helicobacter pylori causes life-long colonisation of the gastric mucosa, leading to chronic inflammation with increased risk of gastric cancer.
Berger, H., Boccellato, F., Denecke, C., Goosmann, C., Imai-Matsushima, A., Meyer, T., Morey, P., Ordemann, J., Sanchez, G., Schmid, M., Woelffling, S.   +10 more
core   +3 more sources

TNFα alters occludin and cerebral endothelial permeability: Role of p38MAPK

PLoS ONE, 2017
Occludin is a key tight junction (TJ) protein in cerebral endothelial cells (CECs) playing an important role in modulating blood-brain barrier (BBB) functions.
Yawen Ni, Tao Teng, Runting Li, Á. Simonyi, G. Sun, James C. Lee   +5 more
semanticscholar   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Altered Expression of Intestinal Tight Junctions in Patients with Chronic Kidney Disease: A Pathogenetic Mechanism of Intestinal Hyperpermeability

Biomedicines
Background: Systemic inflammation in chronic kidney disease (CKD) is associated (as a cause or effect) with intestinal barrier dysfunction and increased gut permeability, with mechanisms not yet fully understood.
Georgia-Andriana Georgopoulou, Marios Papasotiriou, Pinelopi Bosgana, Anne-Lise de Lastic, Eleni-Evangelia Koufou, Evangelos Papachristou, Dimitrios S. Goumenos, Periklis Davlouros, Eleni Kourea, Vasiliki Zolota, Konstantinos Thomopoulos, Athanasia Mouzaki, Stelios F. Assimakopoulos   +12 more
doaj   +1 more source

Testosterone Reduces Tight Junction Complexity and Down-regulates Expression of Claudin-4 and Occludin in the Endometrium in Ovariectomized, Sex-steroid Replacement Rats

In Vivo, 2019
Background/Aim: It was hypothesized that endometrial tight junction morphology and expression of tight junction proteins i.e., claudin-4 and occludin in the uterus, are affected by testosterone.
M. H. Mokhtar, N. Giribabu, N. Salleh
semanticscholar   +1 more source