Results 121 to 130 of about 43,361 (299)
Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells
Clostridium perfringens enterotoxin (CPE) contributes to diarrhea and an often-lethal enterotoxemia. CPE action starts when it binds to claudin receptors, forming a small complex (90 kDa). Six small complexes then oligomerize to create prepores, followed
Iman Mehdizadeh Gohari +4 more
doaj +1 more source
Protein kinase C regulates the phosphorylation and cellular localization of occludin [PDF]
Occludin is an integral membrane phosphoprotein specifically associated with tight junctions, contributing to the structure and function of this intercellular seal.
Mueller, E.C. +4 more
core +1 more source
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke +9 more
wiley +1 more source
A novel basolateral type IV secretion model for the CagA oncoprotein of Helicobacter pylori
Intercellular junctions are crucial structural elements for the formation and maintenance of epithelial barrier functions to control homeostasis or protect against intruding pathogens in humans.
Silja Wessler, Steffen Backert
doaj +1 more source
Cell lysates obtained from A549 cells treated with PBS (mock), TNF-α (10 ng/ml), two dosages of recombinant B19-VP1u and HBoV-VP1u (400 ng/ml and 4000 ng/ml) and bee venom PLA2 (10 ng/ml) were probed with antibodies against occludin.
Bor-Show Tzang (393075) +5 more
core +1 more source
Selenomethionine can ameliorate arachidonic acid‐induced colonic injury through synergistic mechanisms, including alleviating inflammatory responses, improving barrier integrity, enhancing antioxidant capacity by upregulating selenoprotein expression, selectively regulating AA metabolism to reduce pro‐inflammatory oxylipins and promote the production ...
Huihui Tian +8 more
wiley +1 more source
Targeted modulation of the gut microbiome represents a promising nutritional strategy to support metabolic and intestinal health in overweight and obese adults.
Romeo Batacan +4 more
doaj +1 more source
EGCs and GSNO improve expression and localization of occludin in Caco-2 cells. [PDF]
A–B: Caco-2 occludin immunoblot and relative band densities. Cytomix-stimulation decreased occludin expression compared to controls. Co-culture of stimulated-cells with EGCs or incubation with GSNO prevented the Cytomix-induced loss of occludin ...
Gerald A. Cheadle (428902) +5 more
core +1 more source
The aim of our study is to evaluate the interaction between HS and the incorporation of PKM in broiler chicken diets, as well as its effect on growth performance and metabolism. Based on the results obtained, PKM supplementation failed to mitigate the adverse effects of heat stress in broiler chickens. ABSTRACT The aim of this study was to evaluate the
Ahmed Mijiyawa +13 more
wiley +1 more source
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang +6 more
wiley +1 more source

