Results 31 to 40 of about 55,164 (304)

Evaluation of LncRNA uc.173 and Occludin in Iranian Patients with Inflammatory Bowel Disease Compared with Healthy Individuals [PDF]

Journal of Advanced Biomedical Sciences, 2022
Background & Objective: Inflammatory bowel disease (IBD) is characterized by the chronic gastrointestinal inflammation. The two common forms of IBD are ulcerative colitis (UC) and Crohn’s disease (CD) that are distinguished by their location and depth of
Vahid Chaleshi, Saeideh Oloumi Kalantar, Iman Salahshourifar, Shabnam Shahrokh, Hamid Asadzadeh Aghdaei, Mohammad Reza Zali   +5 more
doaj  

Neuregulin-1 attenuates experimental cerebral malaria (ECM) pathogenesis by regulating ErbB4/AKT/STAT3 signaling. [PDF]

, 2018
BACKGROUND:Human cerebral malaria (HCM) is a severe form of malaria characterized by sequestration of infected erythrocytes (IRBCs) in brain microvessels, increased levels of circulating free heme and pro-inflammatory cytokines and chemokines, brain ...
Cespedes, Juan Carlos, Ford, Byron, Liu, Mingli, Solomon, Wesley, Stiles, Jonathan K, Wilson, Nana O   +5 more
core   +1 more source

Occludin phosphorylation: identification of an occludin kinase in brain and cell extracts as CK2

FEBS Letters, 2003
In epithelial and endothelial cells, tight junctions limit paracellular flux of ions, proteins and other macromolecules. However, mechanisms regulating tight junction function are not clear. Occludin, a tight junction protein, undergoes phosphorylation changes in several situations but little is known about occludin kinases.
Smales, Caroline, Ellis, Moira, Baumber, Rachel, Hussain, Nayer, Desmond, Howard, Staddon, James M   +5 more
openaire   +2 more sources

Aerobic training improves blood-brain barrier and neuronal apoptosis in experimental autoimmune encephalomyelitis [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): Blood-brain barrier (BBB) permeability is central in multiple sclerosis (MS) pathophysiology, and exercise may improve BBB integrity. The current study investigated the prophylactic and/ or therapeutic role of aerobic exercise (EX) training
Omid Razi, Abdolhossein Parnow, Iraj Rashidi, Nafiseh Pakravan, Seyed Ershad Nedaei, Robert Motl   +5 more
doaj   +1 more source

Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]

, 2009
Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter, Grove, Joe, Hu, Ke, McKeating, Jane A, Mee, Christopher J, Schwarz, Anne K   +5 more
core   +2 more sources

Artificial rearing influences the morphology, permeability and redox state of the gastrointestinal tract of low and normal birth weight piglets [PDF]

, 2017
Background: In this study the physiological implications of artificial rearing were investigated. Low (LBW) and normal birth weight (NBW) piglets were compared as they might react differently to stressors caused by artificial rearing.
Casteleyn, Christophe, De Smet, Stefaan, Degroote, Jeroen, Fransen, Erik, Michiels, Joris, Prims, Sara, Van Cruchten, Steven, Van Ginneken, Chris, Vergauwen, Hans, Wang, Wei   +9 more
core   +1 more source

Porcine Colostrum Protects the IPEC-J2 Cells and Piglet Colon Epithelium against Clostridioides (syn. Clostridium) difficile Toxin-Induced Effects [PDF]

, 2020
Clostridioides difficile toxins are one of the main causative agents for the clinical symptoms observed during C. difficile infection in piglets. Porcine milk has been shown to strengthen the epithelial barrier function in the piglet’s intestine and may ...
Grześkowiak, Łukasz, Hauser, Anja E., Kröger, Susan, Martínez-Vallespín, Beatriz, Niesner, Raluca, Pieper, Robert, Vahjen, Wilfried, Zentek, Jürgen   +7 more
core   +1 more source

Cinnamon pretreatment modulates gene expression of tight junction proteins in a rat model of stroke [PDF]

Avicenna Journal of Phytomedicine
Objective: Brain ischemia generally results in irreversible brain damage or death. One of the most important features of an ischemic stroke is disruption of the Blood-brain barrier (BBB).
Solmaz Najjary, Hossein Mostafavi, Hadi Feizi, Fatemeh Moradi, Mehdi Eskandari   +4 more
doaj   +1 more source

Human Breast Milk Enhances Intestinal Mucosal Barrier Function and Innate Immunity in a Healthy Pediatric Human Enteroid Model

Frontiers in Cell and Developmental Biology, 2021
Breastfeeding has been associated with long lasting health benefits. Nutrients and bioactive components of human breast milk promote cell growth, immune development, and shield the infant gut from insults and microbial threats. The molecular and cellular
Gaelle Noel, Julie G. In, Julie G. In, Jose M. Lemme-Dumit, Lauren R. DeVine, Robert N. Cole, Anthony L. Guerrerio, James D. Campbell, Olga Kovbasnjuk, Olga Kovbasnjuk, Marcela F. Pasetti   +10 more
doaj   +1 more source

HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal [PDF]

, 2018
Peritoneal fibrosis is a pathological alteration of the peritoneal membrane occurring in a variety of conditions including peritoneal dialysis (PD), post-surgery adhesions and peritoneal metastases.
Battistelli, Cecilia, Bordoni, Veronica, DE TURRIS, Valeria, Domenici, Alessandro, Mai, Antonello, Manzione, Andrea, Mene', Paolo, Moioli, Alessandra, Noce, Valeria, Palladino, Marco, Rossi, Lucia, Strippoli, Raffaele, Tripodi, Marco, Valente, Sergio, Zwergel, Clemens   +14 more
core   +1 more source