Results 11 to 20 of about 56,078 (308)
Occludin 1B, a Variant of the Tight Junction Protein Occludin [PDF]
Molecular Biology of the Cell, 2000 Occludin and claudin are the major integral membrane components of the mammalian tight junction. Although more than 11 distinct claudins have been identified, only 1 occludin transcript has been reported thus far. Therefore, we searched by reverse transcription–PCR for occludin-related sequences in Madin–Darby canine kidney (MDCK) mRNA and identified a
Z, Muresan, D L, Paul, D A, Goodenough
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Low Expression of Occludin in the Melanoma Patient [PDF]
Iranian Journal of Pathology, 2019 Background & Objective: Malignant melanoma is the fatal cutaneous neoplasm which is curable by the early diagnosis. The expression of occludin protein which is an integral membrane protein is altered in an epithelial-to-mesenchymal transition. Although, recent studies provide sufficient evidence supporting the functional importance of occludin in ...
Salehi, Pouri +2 more
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Occludin immunolocalization and protein expression in goldfish [PDF]
Journal of Experimental Biology, 2008 SUMMARYTight junctions (TJs) are an integral component of models illustrating ion transport mechanisms across fish epithelia; however, little is known about TJ proteins in fishes. Using immunohistochemical methods and Western blot analysis, we examined the localization and expression of occludin, a transmembrane TJ protein, in goldfish tissues.
Helen, Chasiotis, Scott P, Kelly
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Occludin Modulates Transepithelial Migration of Neutrophils [PDF]
Journal of Biological Chemistry, 2000 Neutrophils cross epithelial sheets to reach inflamed mucosal surfaces by migrating along the paracellular route. To avoid breakdown of the epithelial barrier, this process requires coordinated opening and closing of tight junctions, the most apical intercellular junctions in epithelia. To determine the function of epithelial tight junction proteins in
Huber D, Balda MS, Matter K
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Frontiers in Physiology, 2020 The blood-brain barrier (BBB) allows the brain to selectively import nutrients and energy critical to neuronal function while simultaneously excluding neurotoxic substances from the peripheral circulation.
Jeffrey J. Lochhead +3 more
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Poultry Science, 2023 : During the transition from incubation to hatch, the chicks shift from obtaining nutrients from the yolk sac to the intestine. The yolk sac tissue (YST) and small intestine serve as biological barriers between the yolk or gut contents and the blood ...
M. Jia, K.L. Reynolds, E.A. Wong
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Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli. [PDF]
, 2016 Pathobiont expansion, such as that of adherent-invasive Escherichia coli (AIEC), is an emerging factor associated with inflammatory bowel disease. The intestinal epithelial barrier is the first line of defense against these pathogens.
McCole, Declan F, Shawki, Ali
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Pharmaceuticals, 2022 In order to promote gastrointestinal health, significant increases in the prevalence of gastrointestinal disorders should be paralleled by similar surges in therapeutics research.
L. Pretorius, C. Smith
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MicroRNA-210 Suppresses Junction Proteins and Disrupts Blood-Brain Barrier Integrity in Neonatal Rat Hypoxic-Ischemic Brain Injury. [PDF]
, 2017 Cerebral edema, primarily caused by disruption of the blood-brain barrier (BBB), is one of the serious complications associated with brain injury in neonatal hypoxic-ischemic encephalopathy (HIE).
Dasgupta, Chiranjib +4 more
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Loss of Occludin Affects Tricellular Localization of Tricellulin [PDF]
Molecular Biology of the Cell, 2008 The tricellular tight junction (tTJ) forms at the convergence of bicellular tight junctions (bTJs) where three epithelial cells meet in polarized epithelia, and it is required for the maintenance of the transepithelial barrier. Tricellulin is a four transmembrane domain protein recently identified as the first marker of tTJ, but little is known about ...
Junichi, Ikenouchi +4 more
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