Occludin Localizes to Centrosomes and Modifies Mitotic Entry [PDF]
Proper control of cell cycle progression and barrier function are essential processes to the maintenance of epithelial cell homeostasis. The contribution of tight junction proteins to barrier function is well established, whereas their contribution to cell cycle control is only beginning to be understood.
E Aaron, Runkle +4 more
openaire +2 more sources
Time-course studies for occludin. [PDF]
(a) The protein levels of occludin from the brain of mice infected with Angiostrongylus cantonensis. β-actin was used as a loading control. (b) Quantification and normalization of occludin to β-actin was performed with a computer-assisted imaging ...
An-Chih Chen (3934331) +4 more
core +1 more source
Occludin: One Protein, Many Forms [PDF]
Intercellular tight junctions (TJs) exhibit a complex molecular architecture involving the regulated cointeraction of cytoplasmic adaptor proteins (e.g., zonula occludens) and integral membrane linker proteins (e.g., occludin and claudins). They provide structural integrity to epithelial and endothelial tissues and create highly polarized barriers ...
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Occludin expression inside Huh7.5 cell laden hydrogels (PF3%, PF7%, PF10%, and P12.5%) at day 20 (Blue: nucleus; red: occludin). [PDF]
Immunofluorescence labelling of each hydrogel sample was performed by applying primary occludin antibody (monoclonal mouse anti-human), secondary antibody (AF 555 rabbit anti-mouse), and DAPI (4',6-diamidino-2-phenylindole).
Nam-Joon Cho (693259) +5 more
core +1 more source
Latar belakang. Obesitas berhubungan dengan perubahan komposisi mikrobiota usus yang dapat mengganggu integritas usus. Protein pengikat tight junction, occludin, ekspresinya berkurang saat integritas usus terganggu. Probiotik dilaporkan dapat memperbaiki
Mira Mariana Ulfah +1 more
doaj +1 more source
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. [PDF]
Occludin is an integral membrane protein localizing at tight junctions (TJ) with four transmembrane domains and a long COOH-terminal cytoplasmic domain (domain E) consisting of 255 amino acids. Immunofluorescence and laser scan microscopy revealed that chick full-length occludin introduced into human and bovine epithelial cells was correctly delivered ...
M, Furuse +6 more
openaire +2 more sources
Claudin-2 and occludin protein expressions. [PDF]
Western blot was used to measure claudin-2 (Fig 6A) and occludin (Fig 6B) protein expressions in intestine. The levels of claudin-2 and occludin in FF and BO groups were significantly decreased compared to the FO group. Claudin-2 and occludin levels were
David Clark (738) +9 more
core +1 more source
E2 treatment leads to occludin cleavage in Huh7.5 cells. [PDF]
(A) Detection of full-length (59 KDa) and truncated (38 KDa) occludin in Huh7.5 cells after treatment with increasing amounts of E2 for 24 hr. (B) Occludin and GAPDH cDNA in Huh7.5 cells following treatment with increasing levels of E2 for 24 hr. NR, RNA/
Manuel M. Lafer (843502) +5 more
core +1 more source
Analysis of occludin trafficking, demonstrating continuous endocytosis, degradation, recycling and biosynthetic secretory trafficking [PDF]
Tight junctions (TJs) link adjacent cells and are critical for maintenance of apical-basolateral polarity in epithelial monolayers. The TJ protein occludin functions in disparate processes, including wound healing and Hepatitis C Virus infection.
Iqbal, Mudassar; id_orcid +4 more
core +6 more sources
Cinnamon pretreatment modulates gene expression of tight junction proteins in a rat model of stroke [PDF]
Objective: Brain ischemia generally results in irreversible brain damage or death. One of the most important features of an ischemic stroke is disruption of the Blood-brain barrier (BBB).
Solmaz Najjary +4 more
doaj +1 more source

