Results 41 to 50 of about 56,078 (308)

Occludin: One Protein, Many Forms [PDF]

Molecular and Cellular Biology, 2012
Intercellular tight junctions (TJs) exhibit a complex molecular architecture involving the regulated cointeraction of cytoplasmic adaptor proteins (e.g., zonula occludens) and integral membrane linker proteins (e.g., occludin and claudins). They provide structural integrity to epithelial and endothelial tissues and create highly polarized barriers ...
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Celiac Disease Monocytes Induce a Barrier Defect in Intestinal Epithelial Cells [PDF]

, 2019
Intestinal epithelial barrier function in celiac disease (CeD) patients is altered. However, the mechanism underlying this effect is not fully understood.
Branchi, Federica, Cardoso-Silva, Danielle, Delbue, Deborah, Itzlinger, Alice, Letizia, Marilena, Schumann, Michael, Siegmund, Britta   +6 more
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Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. [PDF]

The Journal of cell biology, 1994
Occludin is an integral membrane protein localizing at tight junctions (TJ) with four transmembrane domains and a long COOH-terminal cytoplasmic domain (domain E) consisting of 255 amino acids. Immunofluorescence and laser scan microscopy revealed that chick full-length occludin introduced into human and bovine epithelial cells was correctly delivered ...
M, Furuse, M, Itoh, T, Hirase, A, Nagafuchi, S, Yonemura, S, Tsukita, S, Tsukita   +6 more
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Early loss of blood-brain barrier integrity precedes NOX2 elevation in the prefrontal cortex of an animal model of psychosis [PDF]

, 2016
The social isolation rearing of young adult rats is a model of psychosocial stress and provides a nonpharmacological tool to study alterations reminiscent of symptoms seen in psychosis.
Bove, Maria, Cuomo, Vincenzo, Di Giovanni, Giuseppe, Mhillaj, Emanuela, Morgese, Maria Grazia, Neri, Margherita, Pomara, Cristoforo, Schiavone, Stefania, Trabace, Luigia, Tucci, Paolo, Turillazzi, Emanuela, Valentino, Mario   +11 more
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Cinnamon pretreatment modulates gene expression of tight junction proteins in a rat model of stroke [PDF]

Avicenna Journal of Phytomedicine
Objective: Brain ischemia generally results in irreversible brain damage or death. One of the most important features of an ischemic stroke is disruption of the Blood-brain barrier (BBB).
Solmaz Najjary, Hossein Mostafavi, Hadi Feizi, Fatemeh Moradi, Mehdi Eskandari   +4 more
doaj   +1 more source

Brain blood vessel autoantibodies in patients with NMDA and GABAA receptor encephalitis: identification of unconventional Myosin-X as target antigen

Frontiers in Cellular Neuroscience, 2023
Introduction: The antibody repertoire from CSF-derived antibody-secreting cells and memory B-cells in patients with encephalitis contains a considerable number of antibodies that do not target the disease-defining autoantigen such as the GABA or NMDA ...
Lucie Y. Li, Jakob Kreye, Jakob Kreye, Jakob Kreye, Malgorzata Burek, César Cordero-Gomez, César Cordero-Gomez, Paula C. Barthel, Elisa Sánchez-Sendín, Elisa Sánchez-Sendín, Hans-Christian Kornau, Hans-Christian Kornau, Dietmar Schmitz, Dietmar Schmitz, Dietmar Schmitz, Dietmar Schmitz, Dietmar Schmitz, Madeleine Scharf, Patrick Meybohm, S. Momsen Reincke, S. Momsen Reincke, Harald Prüss, Harald Prüss, Markus Höltje   +23 more
doaj   +1 more source

Endocytosis takes occludin for a ride [PDF]

Journal of Cell Biology, 2010
Researchers show how cells remove a tight junction protein to tweak small intestine permeability.
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Enhancing Blood–Brain Barrier Integrity in Patients With Acute Ischemic Stroke Via Normobaric Hyperoxia

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
BACKGROUND Recent advancements in animal studies have demonstrated the potential of normobaric hyperoxia (NBO) as a promising intervention for preserving the integrity of the blood–brain barrier (BBB). However, there is still limited understanding of the
Weili Li, Wenbo Hu, Shuhua Yuan, Jiahao Chen, Qi Wang, Jiayue Ding, Zhiying Chen, Zhifeng Qi, Ju Han   +8 more
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Serum Occludin Level Combined With NIHSS Score Predicts Hemorrhage Transformation in Ischemic Stroke Patients With Reperfusion

Frontiers in Cellular Neuroscience, 2021
Hemorrhagic transformation (HT) is a severe complication following acute ischemic stroke, particularly with reperfusion interventions, leading to poor prognosis.
Shuhua Yuan, Weili Li, Chengbei Hou, Huining Kang, Qingfeng Ma, Xunming Ji, Zhifeng Qi, Ke Jian Liu   +7 more
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Occludin and hydromineral balance inXenopus laevis [PDF]

Journal of Experimental Biology, 2009
SUMMARYTo investigate the response of the tight junction (TJ) protein occludin to environmental change in an anuran amphibian, we examined occludin tissue distribution, immunolocalization and alterations in mRNA expression in African clawed frogs (Xenopus laevis) acclimated to brackish water (BW)conditions (from freshwater to 2‰, 5‰ or 10‰ salt water).
Helen, Chasiotis, Scott P, Kelly
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