Results 21 to 30 of about 46,424 (193)
Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family [PDF]
, 2009 Background: Tight junctions are an intercellular adhesion complex of epithelial and endothelial cells, and form a paracellular barrier that restricts the diffusion of solutes on the basis of size and charge.
Rodrigues, N.T.L. +11 more
core +1 more source
Pharmaceuticals, 2022 In order to promote gastrointestinal health, significant increases in the prevalence of gastrointestinal disorders should be paralleled by similar surges in therapeutics research.
L. Pretorius, C. Smith
doaj +1 more source
Occludin immunolocalization and protein expression in goldfish [PDF]
Journal of Experimental Biology, 2008 SUMMARYTight junctions (TJs) are an integral component of models illustrating ion transport mechanisms across fish epithelia; however, little is known about TJ proteins in fishes. Using immunohistochemical methods and Western blot analysis, we examined the localization and expression of occludin, a transmembrane TJ protein, in goldfish tissues.
Helen, Chasiotis, Scott P, Kelly
openaire +2 more sources
Animals, 2021 We investigated the efficacy of a single bacterium strain, Bacillus subtilis (B. subtilis) YW1, on the performance, morphology, cecal microbiota, and intestinal barrier function of laying hens.
Guangzhi Zhang +12 more
doaj +1 more source
PHD3 inhibits colon cancer cell metastasis through the occludin-p38 pathway
Acta Biochimica et Biophysica Sinica, 2023 Prolyl hydroxylase 3 (PHD3) hydroxylates HIFα in the presence of oxygen, leading to HIFα degradation. PHD3 inhibits tumorigenesis. However, the underlying mechanism is not well understood. Herein, we demonstrate that PHD3 inhibits the metastasis of colon
Li Yuyao +8 more
doaj +1 more source
Pharmaceuticals, 2022 Inflammatory bowel diseases (IBD) are digestive tract disorders that involve chronic inflammation with frequent recurrences. This study aimed to evaluate the efficacy of two novel histone deacetylase 8 (HDAC8) inhibitors, namely, SPA3052 and SPA3074 ...
Ji-In Yoon +3 more
doaj +1 more source
Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors [PDF]
, 2010 Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Christiane Brohm +25 more
core +2 more sources
Frontiers in Nutrition, 2021 Weaning piglets experienced the transformation from breast milk to solid feed and present the proliferation of pathogens, the presence of diarrhea, poor growth performance and even death.
Zhenguo Yang +7 more
doaj +1 more source
Occludin Localizes to Centrosomes and Modifies Mitotic Entry [PDF]
Journal of Biological Chemistry, 2011 Proper control of cell cycle progression and barrier function are essential processes to the maintenance of epithelial cell homeostasis. The contribution of tight junction proteins to barrier function is well established, whereas their contribution to cell cycle control is only beginning to be understood.
E Aaron, Runkle +4 more
openaire +2 more sources
Evaluation of LncRNA uc.173 and Occludin in Iranian Patients with Inflammatory Bowel Disease Compared with Healthy Individuals [PDF]
Journal of Advanced Biomedical Sciences, 2022 Background & Objective: Inflammatory bowel disease (IBD) is characterized by the chronic gastrointestinal inflammation. The two common forms of IBD are ulcerative colitis (UC) and Crohn’s disease (CD) that are distinguished by their location and depth of
Vahid Chaleshi +5 more
doaj