Results 21 to 30 of about 43,361 (299)

Occludin Modulates Transepithelial Migration of Neutrophils [PDF]

open access: yesJournal of Biological Chemistry, 2000
Neutrophils cross epithelial sheets to reach inflamed mucosal surfaces by migrating along the paracellular route. To avoid breakdown of the epithelial barrier, this process requires coordinated opening and closing of tight junctions, the most apical intercellular junctions in epithelia. To determine the function of epithelial tight junction proteins in
Huber D, Balda MS, Matter K
openaire   +3 more sources

Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders

open access: yesFrontiers in Physiology, 2020
The blood-brain barrier (BBB) allows the brain to selectively import nutrients and energy critical to neuronal function while simultaneously excluding neurotoxic substances from the peripheral circulation.
Jeffrey J. Lochhead   +3 more
doaj   +1 more source

Effects of high incubation temperature on tight junction proteins in the yolk sac and small intestine of embryonic broilers

open access: yesPoultry Science, 2023
: During the transition from incubation to hatch, the chicks shift from obtaining nutrients from the yolk sac to the intestine. The yolk sac tissue (YST) and small intestine serve as biological barriers between the yolk or gut contents and the blood ...
M. Jia, K.L. Reynolds, E.A. Wong
doaj   +1 more source

Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family [PDF]

open access: yes, 2009
Background: Tight junctions are an intercellular adhesion complex of epithelial and endothelial cells, and form a paracellular barrier that restricts the diffusion of solutes on the basis of size and charge.
Rodrigues, N.T.L.   +11 more
core   +1 more source

Aspalathus linearis (Rooibos) and Agmatine May Act Synergistically to Beneficially Modulate Intestinal Tight Junction Integrity and Inflammatory Profile

open access: yesPharmaceuticals, 2022
In order to promote gastrointestinal health, significant increases in the prevalence of gastrointestinal disorders should be paralleled by similar surges in therapeutics research.
L. Pretorius, C. Smith
doaj   +1 more source

Loss of Occludin Affects Tricellular Localization of Tricellulin [PDF]

open access: yesMolecular Biology of the Cell, 2008
The tricellular tight junction (tTJ) forms at the convergence of bicellular tight junctions (bTJs) where three epithelial cells meet in polarized epithelia, and it is required for the maintenance of the transepithelial barrier. Tricellulin is a four transmembrane domain protein recently identified as the first marker of tTJ, but little is known about ...
Junichi, Ikenouchi   +4 more
openaire   +2 more sources

Modulatory Effects of Bacillus subtilis on the Performance, Morphology, Cecal Microbiota and Gut Barrier Function of Laying Hens

open access: yesAnimals, 2021
We investigated the efficacy of a single bacterium strain, Bacillus subtilis (B. subtilis) YW1, on the performance, morphology, cecal microbiota, and intestinal barrier function of laying hens.
Guangzhi Zhang   +12 more
doaj   +1 more source

Endocytic occludin recycling. [PDF]

open access: yes, 2014
A confluent monolayer of serum starved MDCK cells were biotinylated then warmed to induce occludin internalisation for 30 minutes followed by biotin removal from plasma membrane proteins.
Sara Jabbari (665782)   +4 more
core   +1 more source

PHD3 inhibits colon cancer cell metastasis through the occludin-p38 pathway

open access: yesActa Biochimica et Biophysica Sinica, 2023
Prolyl hydroxylase 3 (PHD3) hydroxylates HIFα in the presence of oxygen, leading to HIFα degradation. PHD3 inhibits tumorigenesis. However, the underlying mechanism is not well understood. Herein, we demonstrate that PHD3 inhibits the metastasis of colon
Li Yuyao   +8 more
doaj   +1 more source

Stronger expression of occludin. [PDF]

open access: yes, 2013
(A–C) Representative IHC showing occludin signal in blood vessels in ipsilateral penumbral areas (interaural 1.98 mm). Occludin immunoreactivity was stronger in LBP10 group (arrow, C). Inserts, higher magnification of typical blood vessels.
Amy C. Y. Lo (329326)   +6 more
core   +1 more source

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