Results 31 to 40 of about 43,361 (299)
Pharmaceuticals, 2022 Inflammatory bowel diseases (IBD) are digestive tract disorders that involve chronic inflammation with frequent recurrences. This study aimed to evaluate the efficacy of two novel histone deacetylase 8 (HDAC8) inhibitors, namely, SPA3052 and SPA3074 ...
Ji-In Yoon +3 more
doaj +1 more source
Claudin and occludin expression and function in the seminiferous epithelium [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2010 Integral membrane proteins that contribute to function of the blood–testes barrier (BTB) in mice include claudins 3, 5 and 11 and occludin. Although claudin 11 is expressed throughout all stages of the seminiferous epithelial cycle, claudins 3 and 5 have specific expression at stage VIII.
Carla M K, Morrow +3 more
openaire +2 more sources
, 2013 Images of epithelial monolayers, stained with occludin antibodies, either treated with DMSO control (A and C) or SP600125 (B and D). Unstretched monolayers (A and B), exhibit strong staining of Occludin at the cell-cell junction.
Gladys Gray Lawrence (157183) +3 more
core +1 more source
Frontiers in Nutrition, 2021 Weaning piglets experienced the transformation from breast milk to solid feed and present the proliferation of pathogens, the presence of diarrhea, poor growth performance and even death.
Zhenguo Yang +7 more
doaj +1 more source
Occludin: a gatekeeper of brain Infection by HIV-1
Fluids and Barriers of the CNS, 2023 AbstractCompromised structure and function of the blood-brain barrier (BBB) is one of the pathological hallmarks of brain infection by HIV-1. BBB damage during HIV-1 infection has been associated with modified expression of tight junction (TJ) proteins, including occludin. Recent evidence indicated occludin as a redox-sensitive, multifunctional protein
Silvia Torices +8 more
openaire +3 more sources
Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors [PDF]
, 2010 Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Christiane Brohm +25 more
core +1 more source
Occludin is overexpressed in Alzheimer's disease and vascular dementia [PDF]
Journal of Cellular and Molecular Medicine, 2007 AbstractThe tight junctions (TJs) are key players in the control of blood‐brain barrier (BBB) properties, the most complex TJs in the vascular system being found in the endothelial cells of brain capillaries. One of the main TJs proteins is occludin, which anchors plasma membranes of neighbour cells and is present in large amounts in the brain ...
Romanitan, Mihaela Oana +4 more
openaire +2 more sources
Influence of treatment on occludin. [PDF]
, 2019 (a) The protein levels of occludin from the brain of mice infected with Angiostrongylus cantonensis and MG132 treatment. β-actin was used as a loading control.
An-Chih Chen (3934331) +4 more
core +1 more source
Evaluation of LncRNA uc.173 and Occludin in Iranian Patients with Inflammatory Bowel Disease Compared with Healthy Individuals [PDF]
Journal of Advanced Biomedical Sciences, 2022 Background & Objective: Inflammatory bowel disease (IBD) is characterized by the chronic gastrointestinal inflammation. The two common forms of IBD are ulcerative colitis (UC) and Crohn’s disease (CD) that are distinguished by their location and depth of
Vahid Chaleshi +5 more
doaj
Frontiers in Cell and Developmental Biology, 2021 This study aimed to determine whether Bmi-1 deficiency leads to intestinal epithelial barrier destruction and microbiota dysfunction, which members of the microbial community alter barrier function with age, and whether p16INK4a deletion could reverse ...
Jiawen Zhou +14 more
doaj +1 more source