Results 51 to 60 of about 46,424 (193)

Endocytosis takes occludin for a ride [PDF]

Journal of Cell Biology, 2010
Researchers show how cells remove a tight junction protein to tweak small intestine permeability.
openaire   +1 more source

Occludin localization.

, 2013
Images of epithelial monolayers, stained with occludin antibodies, either treated with DMSO control (A and C) or SP600125 (B and D). Unstretched monolayers (A and B), exhibit strong staining of Occludin at the cell-cell junction.
Gladys Gray Lawrence (157183), Amit Khasgiwala (365311), Susan S. Margulies (157185), Taylor S. Cohen (157180)   +3 more
core   +1 more source

Role of Occludin in the Regulation of Epithelial Tight Junctions [PDF]

, 2016
Tight junctions (TJ) constitute the primary component of epithelial barrier function, a disruption of which is involved in the pathogenesis of many gastrointestinal, pulmonary and renal diseases.
Manda, Bhargavi
core   +1 more source

The functional antagonist of sphingosine-1-phosphate, FTY720, impairs gut barrier function

Frontiers in Pharmacology
FTY720 or fingolimod is a known functional antagonist of sphingosine-1-phosphate (S1P), and it is effective in treating multiple sclerosis and preventing inflammatory bowel disease (IBD).
Sohini Sikdar, Debmalya Mitra, Oishika Das, Moumita Bhaumik, Shanta Dutta   +4 more
doaj   +1 more source

The ClC-2 Chloride Channel Activator, Lubiprostone, Improves Intestinal Barrier Function in Biopsies from Crohn’s Disease but Not Ulcerative Colitis Patients

Pharmaceutics, 2023
The prostone analog, lubiprostone, is approved to manage constipation-predominant irritable bowel syndrome. Lubiprostone also protects intestinal mucosal barrier function in animal models of colitis. The aim of this study was to determine if lubiprostone
Young Su Park, Sang Bum Kang, Ronald R. Marchelletta, Harrison M. Penrose, Roos Ruiter-Visser, Barbara Jung, Michael J. Docherty, Brigid S. Boland, William J. Sandborn, Declan F. McCole   +9 more
doaj   +1 more source

Occludin and hydromineral balance inXenopus laevis [PDF]

Journal of Experimental Biology, 2009
SUMMARYTo investigate the response of the tight junction (TJ) protein occludin to environmental change in an anuran amphibian, we examined occludin tissue distribution, immunolocalization and alterations in mRNA expression in African clawed frogs (Xenopus laevis) acclimated to brackish water (BW)conditions (from freshwater to 2‰, 5‰ or 10‰ salt water).
Helen, Chasiotis, Scott P, Kelly
openaire   +2 more sources

Role of Homeobox A1 in Airway Epithelial Generation from Human Airway Basal Cells

Cells
Airway basal cells from chronic obstructive pulmonary disease patients show a reduction in HOXA1 expression and generate an abnormal airway epithelium.
Mohsen Tabasi, Nathaniel Chen, Umadevi Sajjan   +2 more
doaj   +1 more source

Experimental Basis for the High Oral Toxicity of Dinophysistoxin 1: A Comparative Study of DSP

Toxins, 2014
Okadaic acid (OA) and its analogues, dinophysistoxin 1 (DTX1) and dinophysistoxin 2 (DTX2), are lipophilic and heat-stable marine toxins produced by dinoflagellates, which can accumulate in filter-feeding bivalves.
Diego A. Fernández, M. Carmen Louzao, María Fraga, Natalia Vilariño, Mercedes R. Vieytes, Luis M. Botana   +5 more
doaj   +1 more source

Markers of Gut Barrier Function and Microbial Translocation Associate with Lower Gut Microbial Diversity in People with HIV

Viruses, 2021
People with human immunodeficiency virus (HIV) (PWH) have reduced gut barrier integrity (“leaky gut”) that permits diffusion of microbial antigens (microbial translocation) such as lipopolysaccharide (LPS) into the circulation, stimulating inflammation ...
Ronald J. Ellis, Jennifer E. Iudicello, Robert K. Heaton, Stéphane Isnard, John Lin, Jean-Pierre Routy, Sara Gianella, Martin Hoenigl, Rob Knight   +8 more
doaj   +1 more source

Influence of treatment on occludin.

, 2019
(a) The protein levels of occludin from the brain of mice infected with Angiostrongylus cantonensis and MG132 treatment. β-actin was used as a loading control.
An-Chih Chen (3934331), Ling-Yuh Shyu (7252166), Yi-Chieh Lin (461485), Ke-Min Chen (305833), Shih-Chan Lai (386304)   +4 more
core   +1 more source