Results 61 to 70 of about 46,424 (193)

Time-course studies for occludin.

open access: yes, 2019
(a) The protein levels of occludin from the brain of mice infected with Angiostrongylus cantonensis. β-actin was used as a loading control. (b) Quantification and normalization of occludin to β-actin was performed with a computer-assisted imaging ...
An-Chih Chen (3934331)   +4 more
core   +1 more source

Enhancing Blood–Brain Barrier Integrity in Patients With Acute Ischemic Stroke Via Normobaric Hyperoxia

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
BACKGROUND Recent advancements in animal studies have demonstrated the potential of normobaric hyperoxia (NBO) as a promising intervention for preserving the integrity of the blood–brain barrier (BBB). However, there is still limited understanding of the
Weili Li   +8 more
doaj   +1 more source

Occludin expression inside Huh7.5 cell laden hydrogels (PF3%, PF7%, PF10%, and P12.5%) at day 20 (Blue: nucleus; red: occludin).

open access: yes, 2015
Immunofluorescence labelling of each hydrogel sample was performed by applying primary occludin antibody (monoclonal mouse anti-human), secondary antibody (AF 555 rabbit anti-mouse), and DAPI (4',6-diamidino-2-phenylindole).
Nam-Joon Cho (693259)   +5 more
core   +1 more source

Collagen prolyl 4-hydroxylase subunit α member-induced head and neck squamous cell carcinoma aggressiveness is antagonized by LLGL2 via reduced expression of occludin

open access: yesActa Biochimica et Biophysica Sinica
There are three isoforms of human collagen prolyl 4-hydroxylases (C-P4Hs), each of which has been reported to play an important role in regulating the progression of a variety of human cancers. By analyzing TGCA
Xu Miao   +11 more
doaj   +1 more source

Claudin-2 and occludin protein expressions.

open access: yes, 2018
Western blot was used to measure claudin-2 (Fig 6A) and occludin (Fig 6B) protein expressions in intestine. The levels of claudin-2 and occludin in FF and BO groups were significantly decreased compared to the FO group. Claudin-2 and occludin levels were
David Clark (738)   +9 more
core   +1 more source

E2 treatment leads to occludin cleavage in Huh7.5 cells.

open access: yes, 2016
(A) Detection of full-length (59 KDa) and truncated (38 KDa) occludin in Huh7.5 cells after treatment with increasing amounts of E2 for 24 hr. (B) Occludin and GAPDH cDNA in Huh7.5 cells following treatment with increasing levels of E2 for 24 hr. NR, RNA/
Manuel M. Lafer (843502)   +5 more
core   +1 more source

Selected Serum Biomarkers in Patients with Relapsing-Remitting Multiple Sclerosis—A 3-Year Prospective Pilot Study

open access: yesMedical Sciences
Background: The aim of this study was to evaluate the significance of serum concentrations of the inflammatory marker osteopontin, the blood–brain barrier damage marker occludin, and the neurodegeneration marker neurofilament light chain (NFL) in ...
Przemyslaw Puz   +4 more
doaj   +1 more source

Diagram demonstrating occludin trafficking under steady-state conditions.

open access: yes, 2014
During the initial stages of MDCK cell polarisation occludin undergoes endocytosis followed by lysosomal degradation and low-level recycling. This is coupled to occludin biosynthesis in order to maintain plasma membrane occludin homeostasis.
Sara Jabbari (665782)   +4 more
core   +1 more source

Altered Expression of Intestinal Tight Junctions in Patients with Chronic Kidney Disease: A Pathogenetic Mechanism of Intestinal Hyperpermeability

open access: yesBiomedicines
Background: Systemic inflammation in chronic kidney disease (CKD) is associated (as a cause or effect) with intestinal barrier dysfunction and increased gut permeability, with mechanisms not yet fully understood.
Georgia-Andriana Georgopoulou   +12 more
doaj   +1 more source

Tight Junctions Go Viral!

open access: yesViruses, 2015
Tight junctions (TJs) are highly specialized membrane domains involved in many important cellular processes such as the regulation of the passage of ions and macromolecules across the paracellular space and the establishment of cell polarity in ...
Jesús M. Torres-Flores, Carlos F. Arias
doaj   +1 more source

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