Results 61 to 70 of about 43,361 (299)

Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells

The Saudi Journal of Gastroenterology, 2019
Background/Aims: This study was carried out to investigate the effect of Bletilla striata polysaccharide (BSP) treating on lipopolysaccharide (LPS)-induced intestinal epithelial barrier disruption in rat intestinal epithelial cell (IEC) line.
Lei Luo, Yuqing Liu, Xin Cai, Yao Wang, Juan Xue, Juan Zhang, Fan Yang   +6 more
doaj   +1 more source

Maintenance of Intestinal Homeostasis in Diarrhea-Predominant Irritable Bowel Syndrome by Electroacupuncture Through Submucosal Enteric Glial Cell-Derived S-Nitrosoglutathione

Frontiers in Physiology, 2022
Objective: To determine whether electroacupuncture (EA) maintains intestinal homeostasis in diarrhea-predominant irritable bowel syndrome (IBS-D) rats by repairing intestinal barrier function through enteric glial cell (EGC)-derived S-nitrosoglutathione (
Yujun Hou, Ying Zhao, Huiling Jiang, Kai Wang, Wei Zhang, Siyuan Zhou, Ying Li, Qianhua Zheng   +7 more
doaj   +1 more source

Ang-1 diminishes thrombin mediated tyrosine phosphorylation of Occludin. [PDF]

, 2015
(A) Serum starved HBMECs were treated with 100nM thrombin for indicated time periods. Cellular proteins were immunoprecipitated with anti-Occludin antibody followed by immunoblotting using anti-PY-20 antibody.
M. Rizwan Siddiqui (757691), Kwang Sik Kim (18727), Tadanori Tomita (198796), Chandra S. Mayanil (757692)   +3 more
core   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Biochemical Modulators of Tight Junctions (TJs): Occludin, Claudin-2 and Zonulin as Biomarkers of Intestinal Barrier Leakage in the Diagnosis and Assessment of Inflammatory Bowel Disease Progression

Molecules
Background: Considering the increasing worldwide prevalence of inflammatory bowel disease (IBD), the early diagnosis of this disease is extremely important.
Aleksandra Górecka, Agnieszka Jura-Półtorak, Ewa M. Koźma, Anna Szeremeta, Krystyna Olczyk, Katarzyna Komosińska-Vassev   +5 more
doaj   +1 more source

Associations between food-specific IgG antibodies and intestinal permeability biomarkers

Frontiers in Nutrition, 2022
Increasing translational evidence suggests that intestinal permeability may be a contributing factor to systemic inflammatory events and numerous pathologies.
Alexandra Adorno Vita, Heather Zwickey, Ryan Bradley, Ryan Bradley   +3 more
doaj   +1 more source

Hemodynamic regulation of occludin and ZO-1: effect on barrier function [PDF]

, 2006
The vascular endothelium constitutes a highly effective fluid and solute barrier through the regulated apposition of tight junction protein complexes between adjacent endothelial cells.
Collins, Nora
core  

JNK inhibition prevents loss of occludin. [PDF]

, 2013
Occludin concentration in cell monolayers significantly drops following 60 minutes of stretch (0.25 Hz, 37% ΔSA) compared to unstretched monolayers ...
Gladys Gray Lawrence (157183), Amit Khasgiwala (365311), Susan S. Margulies (157185), Taylor S. Cohen (157180)   +3 more
core   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Role of Occludin in the Regulation of Epithelial Tight Junctions [PDF]

, 2016
Tight junctions (TJ) constitute the primary component of epithelial barrier function, a disruption of which is involved in the pathogenesis of many gastrointestinal, pulmonary and renal diseases.
Manda, Bhargavi
core   +2 more sources