Results 61 to 70 of about 67,898 (346)

Occludin and hydromineral balance inXenopus laevis [PDF]

Journal of Experimental Biology, 2009
SUMMARYTo investigate the response of the tight junction (TJ) protein occludin to environmental change in an anuran amphibian, we examined occludin tissue distribution, immunolocalization and alterations in mRNA expression in African clawed frogs (Xenopus laevis) acclimated to brackish water (BW)conditions (from freshwater to 2‰, 5‰ or 10‰ salt water).
Helen, Chasiotis, Scott P, Kelly
openaire   +2 more sources

Enhancing Blood–Brain Barrier Integrity in Patients With Acute Ischemic Stroke Via Normobaric Hyperoxia

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
BACKGROUND Recent advancements in animal studies have demonstrated the potential of normobaric hyperoxia (NBO) as a promising intervention for preserving the integrity of the blood–brain barrier (BBB). However, there is still limited understanding of the
Weili Li, Wenbo Hu, Shuhua Yuan, Jiahao Chen, Qi Wang, Jiayue Ding, Zhiying Chen, Zhifeng Qi, Ju Han   +8 more
doaj   +1 more source

Protective actions of des-acylated ghrelin on brain injury and blood-brain barrier disruption after stroke in mice [PDF]

, 2016
The major ghrelin forms, acylated ghrelin and des-acylated ghrelin, are novel gastrointestinal hormones. Moreover, emerging evidence indicates that these peptides may have other functions including neuro- and vaso-protection.
Andrews, Zane B., Austin, Victoria, Barsby, Tom, Chin, Kai Yee, Ku, Jacqueline M., Miller, Alyson A., Spencer, Sarah J., Taher, Mohammadali, Wong, Connie H.Y.   +8 more
core   +1 more source

Occludin S471 Phosphorylation Contributes to Epithelial Monolayer Maturation [PDF]

Molecular and Cellular Biology, 2016
Multiple organ systems require epithelial barriers for normal function, and barrier loss is a hallmark of diseases ranging from inflammation to epithelial cancers. However, the molecular processes regulating epithelial barrier maturation are not fully elucidated.
Mark T. Bolinger, Aniket Ramshekar, Helen V. Waldschmidt, Scott D. Larsen, Maria C. Bewley, John M. Flanagan, David A. Antonetti   +6 more
openaire   +2 more sources

Expression of Endothelial NOX5 Alters the Integrity of the Blood-Brain Barrier and Causes Loss of Memory in Aging Mice

Antioxidants, 2021
Blood-Brain barrier (BBB) disruption is a hallmark of central nervous system (CNS) dysfunction, and oxidative stress is one of the molecular mechanisms that may underlie this process.
Adriana Cortés, Maite Solas, Álvaro Pejenaute, Miguel A. Abellanas, Marcos Garcia-Lacarte, Maria S. Aymerich, Javier Marqués, María J. Ramírez, Guillermo Zalba   +8 more
doaj   +1 more source

VE-cadherin and claudin-5: it takes two to tango [PDF]

, 2008
Endothelial barrier function requires the adhesive activity of VE-cadherin and claudin-5, which are key components of adherens and tight endothelial junctions, respectively.
A Taddei, AS Yap, D Hoogeboom, E Dejana, J Gavard, J Rhee, J. Silvio Gutkind, Julie Gavard, MAG Essers, MG Lampugnani, P Carmeliet, R Paul, S Tsukita, S van Wetering, S Weis, T Nitta, VV Orlova, WJ Nelson   +17 more
core   +5 more sources

Claudin-5 and occludin levels in patients with psychiatric disorders - A systematic review.

Brain, behavior, and immunity
BACKGROUND Recent research has underscored the critical role of blood-brain barrier (BBB) integrity in psychiatric disorders, highlighting disruptions in tight junction (TJ) proteins, specifically claudin-5 and occludin.
Zinovia Maridaki, Georgios Syrros, Stella Gianna Delichatsiou, J. Warsh, G. Konstantinou   +4 more
semanticscholar   +1 more source

Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells

The Saudi Journal of Gastroenterology, 2019
Background/Aims: This study was carried out to investigate the effect of Bletilla striata polysaccharide (BSP) treating on lipopolysaccharide (LPS)-induced intestinal epithelial barrier disruption in rat intestinal epithelial cell (IEC) line.
Lei Luo, Yuqing Liu, Xin Cai, Yao Wang, Juan Xue, Juan Zhang, Fan Yang   +6 more
doaj   +1 more source

Connexin-Occludin Chimeras Containing the Zo-Binding Domain of Occludin Localize at Mdck Tight Junctions and Nrk Cell Contacts [PDF]

The Journal of Cell Biology, 1999
Occludin is a transmembrane protein of the tight junction that functions in creating both an intercellular permeability barrier and an intramembrane diffusion barrier. Creation of the barrier requires the precise localization of occludin, and a distinct family of transmembrane proteins called claudins, into continuous linear fibrils visible by freeze ...
L L, Mitic, E E, Schneeberger, A S, Fanning, J M, Anderson   +3 more
openaire   +2 more sources

Caco2/HT-29 In Vitro Cell Co-Culture: Barrier Integrity, Permeability, and Tight Junctions’ Composition During Progressive Passages of Parental Cells

Biology
Epithelial linings are crucial for the maintenance of physiological barriers. The intestinal epithelial barrier (IEB) consists of enterocytes through tight junctions and mucus-secreting cells and can undergo physiological modifications throughout life ...
Elena Donetti, Paola Bendinelli, Margherita Correnti, Elena Gammella, Stefania Recalcati, Anita Ferraretto   +5 more
doaj   +1 more source