Results 71 to 80 of about 6,916 (201)

Research Progress on Halide Solid‐State Electrolytes: Synthesis, Mechanism, and Modification

Carbon Energy, Volume 8, Issue 4, April 2026.
This review comprehensively summarizes the research progress on halide solid‐state electrolytes, including their classifications, synthesis methods, ion conduction mechanisms, and modification strategies. It also proposes effective modification strategies to address critical issues, such as air stability and interface compatibility.
Weifeng Shen, Ping Liu, Long Wang, Haijun Yang, Jiawen Chen, Fengxiang Chen, Shenghui Shen, Guoxiang Pan, Zhong Qiu, Xinqi Liang, Yongqi Zhang, Jiayuan Xiang, Ming Song, Wei Wen, Ruyi Fang, Hui Huang, Jun Zhang, Qi Liu, Yang Xia, Wenkui Zhang, Xinhui Xia   +20 more
wiley   +1 more source

Oct1 Is a Switchable, Bipotential Stabilizer of Repressed and Inducible Transcriptional States [PDF]

Journal of Biological Chemistry, 2011
Little is known regarding how the Oct1 transcription factor regulates target gene expression. Using murine fibroblasts and two target genes, Polr2a and Ahcy, we show that Oct1 recruits the Jmjd1a/KDM3A lysine demethylase to catalyze the removal of the inhibitory histone H3K9 dimethyl mark and block repression.
Arvind, Shakya, Jinsuk, Kang, Jeffrey, Chumley, Matthew A, Williams, Dean, Tantin   +4 more
openaire   +2 more sources

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

Conference Report: Sixth Annual Young Researcher Forum of the Japan Society of Medical and Pharmaceutical Sciences for Traditional Medicine

Traditional &Kampo Medicine, Volume 13, Issue 1, April 2026.
ABSTRACT Background Nine young researchers presented their studies in the field of traditional Japanese Kampo medicine (Wakan‐yaku) at the Sixth Annual Young Researcher Forum held the day before the 2025 annual meeting of the Japan Society of Medical and Pharmaceutical Sciences for Traditional Medicine. Main Presentations Dr.
Tetsuhiro Yoshino, Kensuke Nakajima, Kousuke Araki, Tomoki Sekiya, Sakura Takamatsu, Motoya Miyahara, Ryuya Takada, Ryohei Nishimoto, Takumi Nagamatsu, Mebuki Hama, Ximeng Yang, Kazuhito Murakami, Mayumi Kamigaki, Hirokazu Ando, Souichi Nakashima   +14 more
wiley   +1 more source

Screening of OATP1B1/3 and OCT1 inhibitors in cryopreserved hepatocytes in suspension

European Journal of Pharmaceutical Sciences, 2010
Drug-drug interactions involving hepatic drug transporters may have clinical consequences and jeopardize development of promising drug candidates. Organic anion transporting polypeptides (OATP/Oatp) and the organic cation transporters (OCT/Oct) are among the most important transporters involved in xenobiotic uptake in the liver.
Badolo, Lassina, Rasmussen, Louise Munk, Hansen, Helle Rüsz, Sveigaard, Christina   +3 more
openaire   +3 more sources

Bovine Transcription Factor POU Class 2 Homeobox 1 (POU2F1/Oct1) Protein Promotes BoHV-1 Replication in MDBK Cells

Viruses
Bovine herpesvirus type 1 (BoHV-1) causes severe diseases in bovine species and great economic burden to the cattle industry worldwide. Due to its complex life cycle, many host factors that affect BoHV-1 replication remain to be explored.
Enguang Rong, Inga Dry, Robert G. Dalziel, Wenfang Spring Tan   +3 more
doaj   +1 more source

Ethnic Bridging of Sepiapterin in Chinese and Korean Populations Based on Predictions From Genetic Polymorphism of Breast Cancer Resistance Protein

Clinical and Translational Science, Volume 19, Issue 4, April 2026.
ABSTRACT Ethnic differences are crucial when considering the efficacy, safety, and dose of pharmaceuticals across diverse populations. The International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) guideline E5 addresses the acceptability of extrapolating foreign clinical data taking ethnic factors into ...
Lan Gao, Neil Smith, Ronald Kong
wiley   +1 more source

Assessment of Interaction of Human OCT 1-3 Proteins and Metformin using Silico Analyses

Acta Chimica Slovenica, 2020
Metformin, a drug frequently used by diabetic patients as the first-line treatment worldwide, is positively charged and is transported into the cell through human organic cation transporter (hOCT 1-3) proteins.
Faruk Berat Akçeşme, Nail Beşli, Jorge Peña-García, Horacio Pérez-Sánchez   +3 more
doaj   +1 more source

Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao, Hongli Zhang, Yating Yang, Wei‐Dong Chen, Yan‐Dong Wang   +4 more
wiley   +1 more source

BRCA1 through Its E3 Ligase Activity Regulates the Transcription Factor Oct1 and Carbohydrate Metabolism

, 2018
The tumor suppressor BRCA1 regulates the DNA damage response (DDR) and other processes that remain incompletely defined. Among these, BRCA1 heterodimerizes with BARD1 to ubiquitylate targets via its N-terminal E3 ligase activity. Here, it is demonstrated
Karina Vázquez-Arreguín, Thomas Ludwig, Jessica Maddox, Jinsuk Kang, Rachel E. Factor, Dongju Park, Dean Tantin, Reuben R. Cano   +7 more
core   +1 more source