Results 101 to 110 of about 54,485 (283)
COPS2 Antagonizes OCT4 to Accelerate the G2/M Transition of Mouse Embryonic Stem Cells
Stem Cell Reports, 2018 Summary: Proper regulation of the cell cycle is essential to safeguard the genomic integrity of embryonic stem cells (ESCs) while maintaining the fast proliferation rate.
Peng Li +3 more
doaj +1 more source
Principal modes of motion for the Oct4 and Sox2 proteins.
, 2016 (A) Dominant motions of Oct4 and Sox2 in the Oct4/Sox20bp complex. (B) Dominant motions of Oct4 and Sox2 in the Oct4/Sox23bp complex. The magnitudes and directions of motion of the residues are indicated by red arrows in the ribbon structure.
Masaud Shah (390960) +5 more
core +1 more source
Engineering a Bioelectronic Hybrid Heart with Integrated Sensing and Electrical Modulation
Advanced Science, EarlyView.A bioelectronic hybrid heart is engineered by integrating iPSC‐derived cardiomyocytes, a decellularized cardiac scaffold, a cell‐laden ECM coating, and a flexible electronic mesh. The embedded electrodes enable real‐time recording of spontaneous electrical activity and localized stimulation, allowing controlled pacing and modulation of activation ...
Itai Cabilly +7 more
wiley +1 more source
Advanced Intelligent Systems, EarlyView.This review highlights recent advances in automated iPSC culture systems integrating robotics, advanced imaging, artificial intelligence, and process control. These technologies improve reproducibility, scalability, and quality in cell expansion, differentiation, and real‐time monitoring, while emerging AI‐enabled and closed‐loop approaches offer new ...
Hyoryong Lee +3 more
wiley +1 more source
, 2013 Bisulfite sequencing results assessing the DNA methylation status of the Oct4 promoter is shown for the indicated cell types. OSKM = Oct4, Sox2, Klf4, and c-Myc; ESCs = embryonic stem cells; NSCs = neural stem cells.
Daniel Esch (327589) +10 more
core +1 more source
Cell Reports, 2016 The core pluripotency factor Oct4 plays key roles in somatic cell reprogramming through transcriptional control. Here, we profile Oct4 occupancy, epigenetic changes, and gene expression in reprogramming.
Jun Chen +14 more
doaj +1 more source
Advanced NanoBiomed Research, EarlyView.Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang +12 more
wiley +1 more source
, 2018 Zhengyi Ruan, Xingyu Yang, Weiwei Cheng Department of Obstetrics and Gynaecology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China Background: Although surgery, chemotherapy, and ...
Yang X, Ruan Z, Cheng W
core
Oct4 expression in expanded blastocysts and the percentage of blastocysts expressing Oct4.
, 2013 The total blastomeres and the blastomeres expressing Oct4 in expanded blastocysts from ICSI control and four ROSI groups; Bars represent means ± SD (A). Representative images of Oct4 expression in expanded mouse blastocysts derived from ROSI or ICSI (B);
Man-Xi Jiang (475073) +5 more
core +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
BMEMat, EarlyView.Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source