Results 31 to 40 of about 75,125 (295)
GENERATION OF MOUSE INDUCED PLURIPOTENT STEM CELLS BY PROTEIN TRANSDUCTION. [PDF]
, 2013 Somatic cell reprogramming has generated enormous interest after the first report by Yamanaka and his coworkers in 2006 on the generation of induced pluripotent stem cells (iPSCs) from mouse fibroblasts. Here we report the generation of stable iPSCs from
Andras Dinnyes +6 more
core +1 more source
Oct4-Transfection한 중간엽줄기세포 유래 핵이식 배반포의 Oct4 발현 분포 및 세포 자멸사의 변화에 관한 연구
Journal of Animal Reproduction and Biotechnology, 2016 There are various factors i.e. donor cell type, culture system as well as technical procedures which influence the pre-implantation embryonic development; however, may attempts have been made and still it is under investigation to improve the cloning ...
Won-Jae Lee +3 more
doaj +1 more source
Radiology and Oncology, 2016 The data on expression and clinical impact of cancer stem cell markers SOX2, NANOG and OCT4 in lung cancer is still lacking. The aim of our study was to compare SOX2, NANOG and OCT4 mRNA expression levels in whole blood between advanced small-cell lung ...
Sodja Eva +5 more
doaj +1 more source
The roles of long noncoding RNAs in the regulation of OCT4 expression
Stem Cell Research & Therapy, 2022 OCT4 is a major transcription factor that maintains the pluripotency of stem cells, including embryonic stem cells, induced pluripotent stem cells and cancer stem cells. An increasing number of long noncoding RNAs have been reported to participate in the
Rui-Ting Zhou, Yi-Ran Ni, Fan-Jun Zeng
doaj +1 more source
OCT4: A penetrant pluripotency inducer
Cell Regeneration, 2014 Native OCT4 protein has the intrinsic ability of crossing cellular membranes to enter cells. This finding could revive efforts to induce pluripotency with proteins replacing nucleic acid-based approaches, and raises the intriguing question as to whether OCT4 can act non-cell-autonomously.
Jauch, Ralf, Wang, Xuecong
openaire +4 more sources
Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5 [PDF]
Transcription, 2010 Long non-coding RNAs (lncRNAs) have been shown to epigenetically regulate certain genes in human cells. Here we report evidence for the involvement of an antisense lncRNA in the transcriptional regulation of the pluripotency-associated factor Oct4. When an lncRNA antisense to Oct4-pseudogene 5 was suppressed, transcription of Oct4 and Oct4 pseudogenes ...
Peter G, Hawkins, Kevin V, Morris
openaire +2 more sources
Effect of Intracytoplasmic Sperm Injection (ICSI) on Mouse Embryos Preimplantational Development
Scientific Papers Animal Science and Biotechnologies, 2023 It is known that the in vitro culture (IVC) of preimplantation embryos is associated with changes in gene expression. It is however, not known if the method of fertilization affects the global pattern of gene expression.
Claudia Cârste +5 more
doaj
Zhongliu Fangzhi Yanjiu, 2018 Objective To investigate the role of High-mobility group box-1 (HMGB1) protein in regulating the expression of cancer stem cell markers Nanog, OCT4 and Sox2.
WANG Hua +4 more
doaj +1 more source
Human Amniocytes Are Receptive to Chemically Induced Reprogramming to Pluripotency [PDF]
, 2017 Restoring pluripotency using chemical compounds alone would be a major step forward in developing clinical-grade pluripotent stem cells, but this has not yet been reported in human cells.
Adjaye, J +15 more
core +4 more sources
Rationale and Methodology of Reprogramming for Generation of Induced Pluripotent Stem Cells and Induced Neural Progenitor Cells. [PDF]
, 2016 Great progress has been made regarding the capabilities to modify somatic cell fate ever since the technology for generation of induced pluripotent stem cells (iPSCs) was discovered in 2006.
Biswas, Sangita +3 more
core +2 more sources