Deletion of <i>wfs1</i> Impairs Oligodendrocyte Precursor Cells Dorsal Distribution and Myelination Through the <i>wfs1</i>-<i>hmgcs1</i> Axis in Zebrafish. [PDF]
Tang X +7 more
europepmc +1 more source
Progenitor Timing Shapes NG2‐Glia Fate and Oligodendrocyte Differentiation
Developmental timing defines NG2‐glia and oligodendrocyte fate. E16 NG2‐progenitors produce large, more dispersed NG2‐glia clones. P0 progenitors show a bias toward oligodendrocyte differentiation. Temporal windows establish long‐term cortical glial heterogeneity.
Ana Cristina Ojalvo‐Sanz +2 more
wiley +1 more source
Gintonin prevents paclitaxel-induced neuropathic pain via spinal LPA<sub>3</sub> receptors and oligodendrocyte precursor cells in mice. [PDF]
Park KT +5 more
europepmc +1 more source
Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea
Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson +13 more
wiley +1 more source
Effect of transplanted oligodendrocyte precursor cells derived from inflammatory and non-inflammatory microenvironment on remyelination in a chronic cuprizone model. [PDF]
Akbari H +3 more
europepmc +1 more source
The Role of Astrocytes in the Inflammatory Response in Neurodiseases
Reactive astrocyte‐mediated pathogenic mechanisms in neurodegenerative diseases Schematic representation of key astrocytic pathways contributing to pathology in the pathogenesis of AD, PD, ALS, and HD. In AD, astrocytes exhibit Aβ plaque‐associated activation characterized by GFAP/S100β upregulation, accompanied by impaired EAAT2‐mediated glutamate ...
Shijun Peng +3 more
wiley +1 more source
Roles of Ion Channels in Oligodendrocyte Precursor Cells: From Physiology to Pathology. [PDF]
Wang J, Shen Y, Liao P, Yang B, Jiang R.
europepmc +1 more source
Multiple Sclerosis and Viruses: « Liaisons Dangereuses »
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina +11 more
wiley +1 more source
Characterizing hypoxia-orchestrated post-stroke changes in oligodendrocyte precursor cells for optimized cell therapy. [PDF]
Kuwata Y +9 more
europepmc +1 more source
Using the morphometric inverse divergence gradient network (MIND‐Gd), this study shows that adolescents with major depressive disorder (MDD) and non‐suicidal self‐injury (NSSI) exhibit altered principal structural gradients relative to adolescents with MDD without NSSI, and that these gradient changes are spatially coupled to neurotransmitter receptor ...
Yan Zhang +13 more
wiley +1 more source

