Results 21 to 30 of about 9,077 (165)
Oligodendroglia: metabolic supporters of neurons [PDF]
Journal of Clinical Investigation, 2017 Oligodendrocytes are glial cells that populate the entire CNS after they have differentiated from oligodendrocyte progenitor cells. From birth onward, oligodendrocytes initiate wrapping of neuronal axons with a multilamellar lipid structure called myelin.
Jeffrey D. Rothstein, Thomas Philips
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Arquivos de Neuro-Psiquiatria, 2008 The ethidium bromide-demyelinating model (EB) was used to study remyelination in the brainstem under the use of cyclosporine (CsA). Wistar rats were submitted to intracisternal injection of 0.1% EB or 0.9% saline solution, and others were taken as ...
Eduardo Fernandes Bondan +2 more
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Pathology of oligodendroglia: An overview [PDF]
Neuropathology, 2017 Oligodendroglia are cells responsible for creating myelin sheaths for axons in the CNS. However, pathologies of oligodendroglia other than demyelination are not well understood due to the lack of adequate methods of characterizing pathological conditions affecting oligodendroglia in human tissue. This review discusses three major topics with the aim of
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Frontiers in Genetics, 2018 Numerous genetic risk loci are found to associate with major neuropsychiatric disorders represented by schizophrenia. The pathogenic roles of genetic risk loci in psychiatric diseases are further complicated by the association with cell lineage- and/or ...
Xianjun Chen +3 more
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Oligodendroglia and neurotrophic factors in neurodegeneration
Neuroscience Bulletin, 2013 Myelination by oligodendroglial cells (OLs) enables the propagation of action potentials along neuronal axons, which is essential for rapid information flow in the central nervous system. Besides saltatory conduction, the myelin sheath also protects axons against inflammatory and oxidative insults. Loss of myelin results in axonal damage and ultimately
Andrew N. Bankston +2 more
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Redistribution and internalization of antibodies to galactocerebroside by oligodendroglia [PDF]
The Journal of Neuroscience, 1988 Glial cultures from mouse brain were used to examine the direct interaction between oligodendroglia and antibodies to galactocerebroside (GalC). The external surface of oligodendroglial membrane sheets showed large GalC+ patches separated by a GalC- network after exposure to anti-GalC and fluoresceinated second antibody at 37 degrees C.
Joyce A. Benjamins, Charissa A. Dyer
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Altered oligodendroglia and astroglia in chronic traumatic encephalopathy [PDF]
Acta Neuropathologica, 2020 Abstract Chronic traumatic encephalopathy (CTE) is a progressive tauopathy found in contact sport athletes, military veterans, and others exposed to repetitive head impacts (RHI)1–6. White matter atrophy and axonal loss have been reported in CTE but have not been characterized on a molecular or cellular level2,7,8.
K. Blake Chancellor +8 more
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Sleep Disturbance in Bipolar Disorder: Neuroglia and Circadian Rhythms
Frontiers in Psychiatry, 2019 The worldwide prevalence of sleep disorders is approximately 50%, with an even higher occurrence in a psychiatric population. Bipolar disorder (BD) is a severe mental illness characterized by shifts in mood and activity.
Luca Steardo +6 more
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The oligodendroglia cytoskeleton in health and disease [PDF]
Journal of Neuroscience Research, 2000 Oligodendrocytes have a high rate of synthetic activity and produce vast amounts of myelin. The membrane production requires specific sorting and transport processes and structural support. In culture, oligodendrocytes extend flat membranous sheets containing an extensive cytoskeletal network of microtubules (MTs) and microfilaments (MFs).
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BMC Neuroscience, 2018 Background The progressive neurodegenerative disorder multiple system atrophy (MSA) is characterized by α-synuclein-positive (oligodendro-) glial cytoplasmic inclusions (GCIs).
Lisa Fellner +5 more
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