Live-cell metabolic analysis of oligodendroglia isolated from postnatal mouse brain and spinal cord
STAR Protocols, 2022 Summary: This protocol describes isolation and live-cell metabolic analysis of O4+ oligodendroglia from brain and spinal cord of postnatal mice. We have optimized existing protocols for O4+ isolation from neonatal brain and expanded the protocol to ...
Luipa Khandker, Teresa L. Wood
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Autophagy in α-Synucleinopathies—An Overstrained System
Cells, 2021 Alpha-synucleinopathies comprise progressive neurodegenerative diseases, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA).
Lisa Fellner +3 more
doaj +1 more source
Myelination of parvalbumin interneurons shapes the function of cortical sensory inhibitory circuits
Nature Communications, 2020 Myelination optimizes conduction speed of excitatory neurons. However, whether myelination of interneurons (INs) refines cortical networks is unclear.
Najate Benamer +3 more
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Gliogenic Potential of Single Pallial Radial Glial Cells in Lower Cortical Layers
Cells, 2021 During embryonic development, progenitor cells are progressively restricted in their potential to generate different neural cells. A specific progenitor cell type, the radial glial cells, divides symmetrically and then asymmetrically to produce neurons ...
Ana Cristina Ojalvo-Sanz +1 more
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Internalization of exogenous myelin by oligodendroglia promotes lineage progression
Peiró-Moreno C +7 more
europepmc +2 more sources
Glioneuronal apoptosis and neuroinflammation in drug resistant temporal lobe epilepsy
Неврология, нейропсихиатрия, психосоматика, 2023 The study of glioneuronal apoptosis and neuroinflammation is extremely important for understanding the causes of epilepsy. Currently, the focus is on neuronal apoptosis and certain aspects of neuroinflammation, while glial apoptosis remains poorly ...
T. V. Sokolova +9 more
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Disrupted CXCR2 Signaling in Oligodendroglia Lineage Cells Enhances Myelin Repair in a Viral Model of Multiple Sclerosis. [PDF]
, 2019 CXCR2 is a chemokine receptor expressed on oligodendroglia that has been implicated in the pathogenesis of neuroinflammatory demyelinating diseases as well as enhancement of the migration, proliferation, and myelin production by oligodendroglia. Using an
Cheng, Yuting +9 more
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Oligodendroglia: metabolic supporters of axons [PDF]
Trends in Cell Biology, 2013 Axons are specialized extensions of neurons that are critical for the organization of the nervous system. To maintain function in axons that often extend some distance from the cell body, specialized mechanisms of energy delivery are likely to be necessary.
Jeffrey D. Rothstein +2 more
openaire +3 more sources
Placental Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Myelin Regeneration in an Animal Model of Multiple Sclerosis. [PDF]
, 2019 Mesenchymal stem/stromal cells (MSCs) display potent immunomodulatory and regenerative capabilities through the secretion of bioactive factors, such as proteins, cytokines, chemokines as well as the release of extracellular vesicles (EVs).
Barthe, Sylvain +11 more
core +2 more sources
MicroRNA-23a promotes myelination in the central nervous system. [PDF]
, 2013 Demyelinating disorders including leukodystrophies are devastating conditions that are still in need of better understanding, and both oligodendrocyte differentiation and myelin synthesis pathways are potential avenues for developing treatment ...
Fu, Ying-Hui +5 more
core +2 more sources