Results 21 to 30 of about 17,381 (266)
Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility [PDF]
Neuron, 2022 Mandy Meijer +16 more
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BMC Neuroscience, 2018 Background The progressive neurodegenerative disorder multiple system atrophy (MSA) is characterized by α-synuclein-positive (oligodendro-) glial cytoplasmic inclusions (GCIs).
Lisa Fellner +5 more
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Oligodendroglia Are Particularly Vulnerable to Oxidative Damage After Neurotrauma In Vivo
Journal of Experimental Neuroscience, 2018 In the paper “Oligodendroglia are particularly vulnerable to oxidative damage after neurotrauma in vivo,” we determined the extent of oxidative damage to specific cellular subpopulations and structures within regions vulnerable to secondary degeneration ...
Marcus Giacci, Melinda Fitzgerald
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Adenosine Actions on Oligodendroglia and Myelination in Autism Spectrum Disorder
Frontiers in Cellular Neuroscience, 2018 Autism spectrum disorder (ASD) is the most commonly diagnosed neurodevelopmental disorder. Independent of neuronal dysfunction, ASD and its associated comorbidities have been linked to hypomyelination and oligodendroglial dysfunction.
Hai-Ying Shen +4 more
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Phenotype overlap in glial cell populations: astroglia, oligodendroglia and NG-2(+) cells. [PDF]
Frontiers in Neuroanatomy, 2015 The extent to which NG-2(+) cells form a distinct population separate from astrocytes is central to understanding whether this important cell class is wholly an oligodendrocyte precursor cell (OPC) or has additional functions akin to those classically ...
Alix +75 more
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In vivo Optogenetic Approach to Study Neuron-Oligodendroglia Interactions in Mouse Pups
Frontiers in Cellular Neuroscience, 2018 Optogenetic and pharmacogenetic techniques have been effective to analyze the role of neuronal activity in controlling oligodendroglia lineage cells in behaving juvenile and adult mice. This kind of studies is also of high interest during early postnatal
Domiziana Ortolani +8 more
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Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Huntington disease (HD) is a progressive neurodegenerative disorder. While research efforts in HD have largely focused on understanding gray matter atrophy representing neuronal loss, there is clear evidence from human and animal studies ...
Costanza Ferrari Bardile +16 more
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The oligodendroglia cytoskeleton in health and disease [PDF]
Journal of Neuroscience Research, 2000 Oligodendrocytes have a high rate of synthetic activity and produce vast amounts of myelin. The membrane production requires specific sorting and transport processes and structural support. In culture, oligodendrocytes extend flat membranous sheets containing an extensive cytoskeletal network of microtubules (MTs) and microfilaments (MFs).
Christiane Richter‐Landsberg
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Oligodendroglia heterogeneity in the human central nervous system [PDF]
Acta Neuropathologica, 2021 It is the centenary of the discovery of oligodendrocytes and we are increasingly aware of their importance in the functioning of the brain in development, adult learning, normal ageing and in disease across the life course, even in those diseases ...
Luise A. Seeker, Anna Williams
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