Results 31 to 40 of about 17,381 (266)
SCN2A contributes to oligodendroglia excitability and development in the mammalian brain [PDF]
Cell Reports, 2021 Elizabeth Gould, Jun Hee Kim
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Impairment of Oligodendroglia Maturation Leads to Aberrantly Increased Cortical Glutamate and Anxiety-Like Behaviors in Juvenile Mice [PDF]
Frontiers in Cellular Neuroscience, 2015 Adolescence is the critical time for developing proper oligodendrocyte (OL)-neuron interaction and the peak of onset for many cognitive diseases, among which anxiety disorders display the highest prevalence.
Xianjun Chen +9 more
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Frontiers in Neuroscience, 2022 Oligodendroglia play a critical role in CNS homeostasis by myelinating neuronal axons in their mature stages. Dysfunction in this lineage occurs when early stage OPCs are not able to differentiate to replace dying Mature Myelinating Oligodendrocytes ...
Miguel M. Madeira +7 more
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The contribution of DNA methylation to the (dys)function of oligodendroglia in neurodegeneration
Acta Neuropathologica Communications, 2023 Neurodegenerative diseases encompass a heterogeneous group of conditions characterised by the progressive degeneration of the structure and function of the central or peripheral nervous systems. The pathogenic mechanisms underlying these diseases are not
Katherine Fodder +3 more
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Frontiers in Neuroscience, 2021 Increasing evidence has demonstrated that in addition to dysfunction of neuronal circuitry, oligodendroglial dysfunction and/or disruption of white matter integrity are found in the brains of patients with schizophrenia.
Xianjun Chen +8 more
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Glial and Vascular Cell Regulation of the Blood-Brain Barrier in Diabetes [PDF]
Diabetes & Metabolism Journal, 2022 As a structural barrier, the blood-brain barrier (BBB) is located at the interface between the brain parenchyma and blood, and modulates communication between the brain and blood microenvironment to maintain homeostasis.
Xiaolong Li +3 more
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Oligodendroglial Heterogeneity in Neuropsychiatric Disease
Life, 2021 Oligodendroglia interact with neurons to support their health and maintain the normal functioning of the central nervous system (CNS). Human oligodendroglia are a highly heterogeneous population characterised by distinct developmental origins and ...
Sunniva M. K. Bøstrand, Anna Williams
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Interactions Between Astrocytes and Oligodendroglia in Myelin Development and Related Brain Diseases
Neuroscience Bulletin, 2022 Astrocytes (ASTs) and oligodendroglial lineage cells (OLGs) are major macroglial cells in the central nervous system. ASTs communicate with each other through connexin (Cx) and Cx-based network structures, both of which allow for quick transport of ...
Xuelian Hu +3 more
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Myelination of parvalbumin interneurons shapes the function of cortical sensory inhibitory circuits
Nature Communications, 2020 Myelination optimizes conduction speed of excitatory neurons. However, whether myelination of interneurons (INs) refines cortical networks is unclear.
Najate Benamer +3 more
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Autophagy in α-Synucleinopathies—An Overstrained System
Cells, 2021 Alpha-synucleinopathies comprise progressive neurodegenerative diseases, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA).
Lisa Fellner +3 more
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