Results 41 to 50 of about 15,075 (153)

Pozícionális gének aktivitásának szerepe az idegsejt-fenotípus meghatározásában = Role of positional genes in the determination of the neuronal phenotype [PDF]

, 2012
A jellegzetes mintázatban aktiválódó pozícionális gének agyfejlődésben játszott szerepét vizsgálva az alábbi eredményeket nyertük: 1. A korai NE-4C embrionális idegi őssejtek indukálatlan állapotban regionálisan nem elkötelezettek; a neuron-képzés ...
Demeter, Kornél, Herberth, Balázs, Hádinger, Nóra, Környei, Zsuzsanna, Madarász, Emília, Markó, Károly, Varga, Balázs Viktor, Zádori, Anita   +7 more
core  

Markers for OLN-93 oligodendroglia differentiation

Developmental Brain Research, 2005
Oligodendrocytes are target cells in the pathogenesis of multiple sclerosis (MS), a chronic demyelinating disease of the central nervous system (CNS). During the course of the disease, inflammatory mediators may damage oligodendrocytes and their myelin sheaths.
van Meeteren, M.E., Koetsier, M.A., Dijkstra, C.D., van Tol, E.A.   +3 more
openaire   +5 more sources

Deciphering SCN2A: A comprehensive review of rodent models of Scn2a dysfunction

Epilepsia, Volume 66, Issue 12, Page 4624-4638, December 2025.
Abstract SCN2A encodes for the alpha subunit of the voltage‐gated sodium channel NaV1.2, which is involved in action potential initiation and backpropagation in excitatory neurons. Currently, it is one of the highest monogenetic risk factors for both epilepsy and autism spectrum disorder.
Katelin E. J. Scott, Maria Fernanda Hermosillo Arrieta, Aislinn J. Williams   +2 more
wiley   +1 more source

Trigeminal neuralgia - diagnosis and treatment [PDF]

, 2017
Introduction Trigeminal neuralgia (TN) is characterized by touch-evoked unilateral brief shock-like paroxysmal pain in one or more divisions of the trigeminal nerve. In addition to the paroxysmal pain, some patients also have continuous pain.
Bendtsen, Lars, Cruccu, Giorgio, DI STEFANO, Giulia, Maarbjerg, Stine   +3 more
core   +1 more source

Brain and retina in Alzheimer's disease: Pathological intersections and estimates from imaging

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract Recent studies have highlighted retinal optical coherence tomography (OCT) imaging as a promising biomarker for the early detection of Alzheimer's disease (AD). This review connects AD brain pathology – particularly amyloid beta (Aβ), tau, and vascular changes – with corresponding retinal changes.
M. Amin Banihashemi, Saffire H. Krance, Patrick Xiang Ji, Morgan Koo, Julie Ottoy, Richard H. Swartz, Peter J. Kertes, Christopher Hudson, Maged Goubran, Sandra E. Black   +9 more
wiley   +1 more source

Induction of annexin-1 at transcriptional and posttranscriptional level in rat brain by methylprednisolone and the 21-aminosteroid U74389F [PDF]

, 2016
Jan Kornelis de Cock ...
Go, KG, Parente, L, Ruiters, MHJ, Solito, E, TerHorst, GJ, Voermans, PH   +5 more
core  

Trisomy 19 ependymoma, a newly recognized genetico-histological association, including clear cell ependymoma [PDF]

, 2007
Ependymal tumors constitute a clinicopathologically heterogeneous group of brain tumors. They vary in regard to their age at first symptom, localization, morphology and prognosis. Genetic data also suggests heterogeneity.
Chapon, F, Ellison, D, Figarella-Branger, D, Godfraind, C, Lacroix, C, Mikol, J, Palm, T, Rousseau, E, Ruchoux, MM, Salmon, I, Scaravilli, F, Vikkula, M   +11 more
core   +3 more sources

Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways

PROTEOMICS, Volume 25, Issue 21-22, Page 214-229, November 2025.
ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu, Kyungdo Kim, Nicholas Asiimwe, Chan Hyun Na   +3 more
wiley   +1 more source

Polyunsaturated fatty acids in the pathogenesis and treatment of multiple sclerosis [PDF]

, 2007
Epidemiological, biochemical, animal model and clinical trial data described in this overview strongly suggest that polyunsaturated fatty acids, particularly n-6 fatty acids, have a role in the pathogenesis and treatment of multiple sclerosis (MS).
Copeland, Esparza, Fitzgerald, Harbige, Harbige, Jones, Karpus, Laurence S. Harbige, Mohammad K. Sharief, Mokhtarian, Ovadia, Santambrogio, Selmaj, Serafina, Thompson, Thompson, Vartanian   +16 more
core   +2 more sources

What determines the timing of epilepsy surgery in children with cortical malformations and low‐grade epilepsy‐associated tumors?

Epilepsia Open, Volume 10, Issue 5, Page 1345-1352, October 2025.
Abstract Objectives Timely referral and efficient presurgical evaluation are important to optimize postoperative seizure and developmental outcomes in epilepsy surgery patients. We aimed to identify determinants of time intervals from epilepsy diagnosis to referral to specialized centers and epilepsy surgery in children with malformations of cortical ...
Maurits W. C. B. Sanders, Matyas Ebel, Aswin Chari, Merel Fleumer, Anca M. Vasilica, Maria H. Eriksson, Martin Tisdall, Barbora Splitkova, Anezka Belohlavkova, Willem M. Otte, Floor E. Jansen, J. Helen Cross, Kees P. J. Braun, Pavel Krsek   +13 more
wiley   +1 more source