Results 51 to 60 of about 9,077 (165)
In vivo Optogenetic Approach to Study Neuron-Oligodendroglia Interactions in Mouse Pups
Frontiers in Cellular Neuroscience, 2018 Optogenetic and pharmacogenetic techniques have been effective to analyze the role of neuronal activity in controlling oligodendroglia lineage cells in behaving juvenile and adult mice. This kind of studies is also of high interest during early postnatal
Domiziana Ortolani +8 more
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Borna disease virus infection perturbs energy metabolites and amino acids in cultured human oligodendroglia cells. [PDF]
PLoS ONE, 2012 BACKGROUND: Borna disease virus is a neurotropic, non-cytolytic virus that has been widely employed in neuroscientific research. Previous studies have revealed that metabolic perturbations are associated with Borna disease viral infection.
Rongzhong Huang +12 more
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Unprecedented Combination of Rare Degenerative Pathologies in an Octogenarian Ex‐Football Player
Neuropathology, EarlyView.ABSTRACT A 79‐year‐old former professional football player presented with language deficits and cognitive changes. A year later, he had difficulty completing sentences, and 3 years after onset, was reduced to one‐word answers. He developed severe apathy and agitation, and became more impulsive.
Shelley L. Forrest +6 more
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Adenosine Actions on Oligodendroglia and Myelination in Autism Spectrum Disorder
Frontiers in Cellular Neuroscience, 2018 Autism spectrum disorder (ASD) is the most commonly diagnosed neurodevelopmental disorder. Independent of neuronal dysfunction, ASD and its associated comorbidities have been linked to hypomyelination and oligodendroglial dysfunction.
Hai-Ying Shen +4 more
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Blood exosome connexins and small RNAs related to demyelinating disease activity
Annals of Clinical and Translational Neurology, Volume 12, Issue 3, Page 538-555, March 2025.Abstract Objectives To assess blood exosome (Ex)‐connexin (Cx)43 (encoded by GJA1) and its truncated isoforms in multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD), which show distinct alterations in astroglial Cx43. Methods Serum Exs from 48 patients with MS (34 relapsing–remitting, 14 secondary‐progressive), 35 with NMOSD, 20 ...
Guzailiayi Maimaitijiang +12 more
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Advanced Science, Volume 12, Issue 10, March 13, 2025.BACH1, a basic leucine zipper protein ubiquitously expressed in mammalian tissues, plays a critical role in the regulation of oxidative stress, cell cycle progression, heme homeostasis, and immune responses. It is implicated in cardiovascular diseases, cancer progression, neurodegenerative disorders, and many other diseases.
Xiangxiang Wei +9 more
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Heterogeneity of mature oligodendrocytes in the central nervous system
Neural Regeneration ResearchMature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous system.
Chao Weng +6 more
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Mosaic subventricular origins of forebrain oligodendroglia
Frontiers in Neuroscience, 2016 In the perinatal as well as the adult CNS, the subventricular zone (SVZ) of the forebrain is the largest and most active source of neural stem cells (NSCs) that generates neurons and oligodendrocytes (OLs), the myelin forming cells of the CNS.
Kasum eAzim +2 more
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Journal of Comparative Neurology, Volume 533, Issue 3, March 2025.In the telencephalon, apical specializations such as cilia, primary cilia, and microvilli with varying morphologies were observed. Goblet‐like cells, arranged in a single row along the ventricular wall, contained secretory vesicles in their apical regions. Light microscopy demonstrated that these secretory vesicles had a carbohydrate‐rich structure, as
Arife Ahsen Kaplan +3 more
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Stem Cell Reports, 2019 Summary: The process of oligodendrogenesis has been relatively well delineated in the rodent brain. However, it remains unknown whether analogous developmental processes are manifested in the human brain.
Hyosung Kim +6 more
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