Prominin-1 (CD133) Defines Both Stem and Non-Stem Cell Populations in CNS Development and Gliomas [PDF]
, 2014 Prominin-1 (CD133) is a commonly used cancer stem cell marker in central nervous system (CNS) tumors including glioblastoma (GBM). Expression of Prom1 in cancer is thought to parallel expression and function in normal stem cells.
Haidar, Sam +6 more
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Tyro3 deletion is protective in experimental autoimmune encephalomyelitis
Immunology &Cell Biology, Volume 103, Issue 9, Page 857-870, October 2025.Multiple sclerosis pathogenesis involves the complex interplay between the peripheral immune response and the central nervous system. Gas6 is a promising therapy to promote remyelination; however, Gas6 and its receptors (the TAM receptor family) are widely expressed in both immune cells and the central nervous system. Our study demonstrates that global
Michele D Binder +7 more
wiley +1 more source
A dementia neuropathológiája Parkinson-syndromákban = Neuropathology of dementia in Parkinson's syndromes [PDF]
, 2008 Vizsgálatainkban Parkinson-syndromákban (multiszisztémás atrophia, Parkinson-kór, progresszív supranuclearis bénulás, vascularis parkinsonismus (Binswanger-betegség) a dementia neuropathológiai hátterét objektív sejtszámlálási módszerekkel vizsgáltuk, az
Csillik, Anita +4 more
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Mosaic Subventricular Origins of Forebrain Oligodendrogenesis [PDF]
, 2016 In the perinatal as well as the adult CNS, the subventricular zone (SVZ) of the forebrain is the largest and most active source of neural stem cells (NSCs) that generates neurons and oligodendrocytes (OLs), the myelin forming cells of the CNS.
Benedikt Berninger +2 more
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Fundamental Neurochemistry Review: Sphingolipids and Ceramides in Brain Development
Journal of Neurochemistry, Volume 169, Issue 10, October 2025.Ceramides and sphingolipids in brain development and cell compartments. Ceramides and sphingolipids are known to influence multiple steps of brain development, including the formation of the neural tube, neural stem cell polarity and proliferation at the ventricular boundary, neuronal migration—for example, whilst migrating on radial glial processes ...
Kaviya Chinnappa +2 more
wiley +1 more source
Distinctive Structural and Molecular Features of Myelinated Inhibitory Axons in Human Neocortex. [PDF]
, 2018 Numerous types of inhibitory neurons sculpt the performance of human neocortical circuits, with each type exhibiting a constellation of subcellular phenotypic features in support of its specialized functions.
Chang, Edward F +9 more
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The bornavirus-derived human protein EBLN1 promotes efficient cell cycle transit, microtubule organisation and genome stability. [PDF]
, 2016 It was recently discovered that vertebrate genomes contain multiple endogenised nucleotide sequences derived from the non-retroviral RNA bornavirus.
A Aswad +33 more
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Oligodendroglia: new players in amyotrophic lateral sclerosis [PDF]
Brain, 2013 The contribution of glial cells to the neuropathology and phenotype of amyotrophic lateral sclerosis (ALS) has become a focus for basic and translational research. Whereas astrocytes and microglia are studied in great detail, the contribution of oligodendrocytes has been relatively neglected.
openaire +2 more sources
FTY720 (fingolimod) modulates the severity of viral-induced encephalomyelitis and demyelination. [PDF]
, 2014 BackgroundFTY720 (fingolimod) is the first oral drug approved by the Food and Drug Administration for treatment of patients with the relapsing-remitting form of the human demyelinating disease multiple sclerosis.
Blanc, Caroline A +2 more
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Herstellung und Charakterisierung von menschlichen Oligodendrozyten-Vorläuferzellinien [PDF]
, 2006 Bei der Multiplen Sklerose kommen im Verlauf der Erkrankung das Myelin und die Oligodendrozyten zu Schaden. Zu Beginn der Erkrankung kann man Remyelinisierungsvorgänge beobachten.
Onischke, Claus, Sommer, N. (Prof)
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