Results 61 to 70 of about 17,381 (266)
Oxygen impairs oligodendroglial development via oxidative stress and reduced expression of HIF-1α [PDF]
, 2017 The premature increase of oxygen tension may contribute to oligodendroglial precursor cell (OPC) damage in preterm infants. Fetal OPCs are exposed to low oxygen tissue tensions not matched when cells are cultured in room air.
Brill, Christina +4 more
core +2 more sources
Frontiers in Psychiatry, 2020 Epigenetic alterations and impaired oligodendroglial myelination in the prefrontal cortex have been shown to correlate with behavioral and cognitive dysfunctions in social deprivation.
Xianjun Chen +10 more
doaj +1 more source
Oligodendroglial Energy Metabolism and (re)Myelination
Life, 2021 Central nervous system (CNS) myelin has a crucial role in accelerating the propagation of action potentials and providing trophic support to the axons. Defective myelination and lack of myelin regeneration following demyelination can both lead to axonal ...
Vanja Tepavčević
doaj +1 more source
Adult mesenchymal stem cell therapy for myelin repair in Multiple Sclerosis. [PDF]
, 2012 Multiple sclerosis (MS) is a demyelinating immune-mediated disease of the central nervous system (CNS). It is the most frequent neurological disease in young adults and affects over 2 million people worldwide.
Aigner, Ludwig, Rivera, Francisco J
core +2 more sources
SIRT2, tubulin deacetylation, and oligodendroglia differentiation [PDF]
Cell Motility, 2007 AbstractThe mammalian silent information regulator 2 (SIRT2) is an NAD‐dependent histone deacetylase with known roles in the regulation of the cell cycle. SIRT2 is also a tubulin deacetylase functioning as an early mitotic checkpoint, but its roles in regulating cytoplasmic microtubule dynamics were unknown.
Bor Luen Tang, Christelle En Lin Chua
openaire +3 more sources
Melanocortins, Melanocortin Receptors and Multiple Sclerosis
Brain Sciences, 2017 The melanocortins and their receptors have been extensively investigated for their roles in the hypothalamo-pituitary-adrenal axis, but to a lesser extent in immune cells and in the nervous system outside the hypothalamic axis.
Robert P. Lisak, Joyce A. Benjamins
doaj +1 more source
Glia and alpha-synuclein in neurodegeneration: A complex interaction [PDF]
, 2016 α-Synucleinopathies (ASP) comprise adult-onset, progressive neurodegenerative disorders such as Parkinson's disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA) that are characterized by α-synuclein (AS) aggregates in neurons ...
Brück, Dominik +3 more
core +1 more source
Uncovering the Role of Sox2 in Oligodendroglia [PDF]
The Journal of Neuroscience, 2018 In the CNS, oligodendrocytes are responsible for the formation of myelin. To build these insulating sheaths surrounding axons, cells of the oligodendrocyte lineage must go through an intricate and temporally matched sequence of proliferation, migration, differentiation, and myelination ...
openaire +3 more sources
Ion activities and potassium uptake mechanisms of glial cells in guinea-pig olfactory cortex slices. [PDF]
, 1987 1. Double-barrelled ion-sensitive micro-electrodes were used to measure changes in the intracellular activities of K+, Na+ and Cl- (aiK, aiNa, aiCl) in glial cells of slices from guinea-pig olfactory cortex during repetitive stimulation of the lateral ...
Ballanyi, Klaus +2 more
core +2 more sources
MicroRNA miR-204 regulates proliferation and differentiation of oligodendroglia in culture.
Glia, 2020 Oligodendrocytes wrap and physically shield axons of the central nervous system with myelin sheaths, resulting in rapid signal transduction and accurate neuronal function.
Jan Wittstatt +3 more
semanticscholar +1 more source