Results 71 to 80 of about 9,077 (165)
In vitro heterogeneity of human oligodendroglia
, 2023 Oligodendrocytes in the central nervous system (CNS) wrap their plasma membrane extensions around large calibre neuronal axons formulating the multi-layered myelin sheath. Myelin is essential since it allows fast conduction of action potentials and it also provides metabolic support to the environmentally isolated neuronal axon.
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Markers for OLN-93 oligodendroglia differentiation
Developmental Brain Research, 2005 Oligodendrocytes are target cells in the pathogenesis of multiple sclerosis (MS), a chronic demyelinating disease of the central nervous system (CNS). During the course of the disease, inflammatory mediators may damage oligodendrocytes and their myelin sheaths.
van Meeteren, M.E. +3 more
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Frontiers in Cellular Neuroscience, 2015 As a multifactorial disease, the underlying causes of schizophrenia require analysis by multiplex methods such as proteomics to allow identification of whole protein networks.
Paul C Guest +6 more
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Oligodendroglia: new players in amyotrophic lateral sclerosis [PDF]
Brain, 2013 The contribution of glial cells to the neuropathology and phenotype of amyotrophic lateral sclerosis (ALS) has become a focus for basic and translational research. Whereas astrocytes and microglia are studied in great detail, the contribution of oligodendrocytes has been relatively neglected.
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Neuropsychiatric Disease and Treatment, 2018 Yuan Zhou,1 Ning Li,2 Lin Zhu,3 Yixing Lin,3 Huilin Cheng1 1Department of Neurosurgery, Jinling Hospital, Jinling School of Clinical Medicine, Nanjing Medical University, Jiangsu, China; 2Department of Surgery, Li Ka Shing Faculty of Medicine, The ...
Zhou Y, Li N, Zhu L, Lin Y, Cheng H
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PD-1 regulates neural damage in oligodendroglia-induced inflammation.
PLoS ONE, 2009 We investigated the impact of immune regulatory mechanisms involved in the modulation of the recently presented, CD8+ lymphocyte mediated immune response in a mouse model of oligodendropathy-induced inflammation (PLPtg-mutants). The focus was on the role
Antje Kroner +7 more
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The Endocannabinoid System and Oligodendrocytes in Health and Disease
Frontiers in Neuroscience, 2018 Cannabinoid-based interventions are being explored for central nervous system (CNS) pathologies such as neurodegeneration, demyelination, epilepsy, stroke, and trauma. As these disease states involve dysregulation of myelin integrity and/or remyelination,
Alexander A. Ilyasov +7 more
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A 53‐year‐old woman with a 16‐year history of epilepsy
Brain Pathology, Volume 35, Issue 1, January 2025.
Rong Ge +4 more
wiley +1 more source
Neurobiology of Disease, 2021 Barbiturates and benzodiazepines are potent GABAA receptor agonists and strong anticonvulsants. In the developing brain they can cause neuronal and oligodendroglia apoptosis, impair synaptogenesis, inhibit neurogenesis and trigger long-term ...
Kevin K. Noguchi +12 more
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Neurobiology of Disease, 2006 A novel population of hippocampal precursor cells (HPCs) that can be induced to differentiate into astrocytes and oligodendrocytes can be derived from hippocampal cultures grown in serum-free media.
Henry C. Tseng +5 more
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