Results 71 to 80 of about 10,025 (191)

Tyro3 deletion is protective in experimental autoimmune encephalomyelitis

open access: yesImmunology &Cell Biology, Volume 103, Issue 9, Page 857-870, October 2025.
Multiple sclerosis pathogenesis involves the complex interplay between the peripheral immune response and the central nervous system. Gas6 is a promising therapy to promote remyelination; however, Gas6 and its receptors (the TAM receptor family) are widely expressed in both immune cells and the central nervous system. Our study demonstrates that global
Michele D Binder   +7 more
wiley   +1 more source

Fundamental Neurochemistry Review: Sphingolipids and Ceramides in Brain Development

open access: yesJournal of Neurochemistry, Volume 169, Issue 10, October 2025.
Ceramides and sphingolipids in brain development and cell compartments. Ceramides and sphingolipids are known to influence multiple steps of brain development, including the formation of the neural tube, neural stem cell polarity and proliferation at the ventricular boundary, neuronal migration—for example, whilst migrating on radial glial processes ...
Kaviya Chinnappa   +2 more
wiley   +1 more source

Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates

open access: yesActa Neuropathologica Communications, 2017
Multiple system atrophy (MSA) is a horrible and unrelenting neurodegenerative disorder with an uncertain etiology and pathophysiology. MSA is a unique proteinopathy in which alpha-synuclein (α-syn) accumulates preferentially in oligodendroglia rather ...
Ronald J. Mandel   +7 more
doaj   +1 more source

Oligodendroglia: new players in amyotrophic lateral sclerosis [PDF]

open access: yesBrain, 2013
The contribution of glial cells to the neuropathology and phenotype of amyotrophic lateral sclerosis (ALS) has become a focus for basic and translational research. Whereas astrocytes and microglia are studied in great detail, the contribution of oligodendrocytes has been relatively neglected.
openaire   +2 more sources

The contribution of DNA methylation to the (dys)function of oligodendroglia in neurodegeneration [PDF]

open access: gold, 2023
Katherine Fodder   +3 more
openalex   +1 more source

Editorial: Non-neuronal cell heterogeneity in the nervous system during health and disease

open access: yesFrontiers in Cellular Neuroscience, 2022
Greg J. Duncan   +6 more
doaj   +1 more source

Injuring neurons induces neuronal differentiation in a population of hippocampal precursor cells in culture

open access: yesNeurobiology of Disease, 2006
A novel population of hippocampal precursor cells (HPCs) that can be induced to differentiate into astrocytes and oligodendrocytes can be derived from hippocampal cultures grown in serum-free media.
Henry C. Tseng   +5 more
doaj   +1 more source

Oligodendroglia Are Particularly Vulnerable to Oxidative Damage After Neurotrauma In Vivo

open access: yesJournal of Experimental Neuroscience, 2018
In the paper “Oligodendroglia are particularly vulnerable to oxidative damage after neurotrauma in vivo,” we determined the extent of oxidative damage to specific cellular subpopulations and structures within regions vulnerable to secondary degeneration ...
Marcus Giacci, Melinda Fitzgerald
doaj   +1 more source

Plasmalogenase activities in neuronal perikarya, astroglia, and oligodendroglia isolated from bovine brain

open access: yesJournal of Lipid Research, 1977
Plasmalogenase (EC 3.3.2.-, 1-alk-1′-enyl-2-acyl-sn-glycero-3-phosphorylethanolamine aldehydrogendrolase) activities were assayed with the plasmalogens in dispersed myelin as the substrate.
R V Dorman, A D Toews, L A Horrocks
doaj   +1 more source

Upscaling biological complexity to boost neuronal and oligodendroglia maturation and improve in vitro developmental neurotoxicity (DNT) evaluation

open access: green, 2022
Carolina Nunes   +7 more
openalex   +2 more sources

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