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Monosodium glutamate-mediated Ca<sup>2+</sup>-dependent intestinal epithelial ion transports in health and IBS-D in male mice. [PDF]
Wang Y, Chu F, Gong Y, Guo R, Dong H.
europepmc +1 more source
ORAI channels and cancer [PDF]
Cancer is a major cause of death. The diversity of cancer types and the propensity of cancers to acquire resistance to therapies, including new molecularly targeted and immune-based therapies, drives the search for new ways to understand cancer progression.
Gregory Monteith, Silke Chalmers
exaly +7 more sources
Redox modulation of STIM-ORAI signaling [PDF]
STIM1 and ORAI1 constitute the core machinery of the ubiquitous store-operated calcium entry pathway and loss of function in these proteins is associated with severe immune and muscular disorders.
Rajesh Bhardwaj +2 more
exaly +5 more sources
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The STIM-Orai Pathway: The Interactions Between STIM and Orai
Advances in Experimental Medicine and Biology, 2017A primary Ca2+ entry pathway in non-excitable cells is established by the Ca2+ release-activated Ca2+ channels. Their two limiting molecular components include the Ca2+-sensor protein STIM1 located in the endoplasmic reticulum and the Orai channel in the plasma membrane.
Marc Fahrner +2 more
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Revista Pai Inácio de Literatura e Arte, 2021
Trabalho submetido à Revista Pai Inácio de Literatura e ...
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Trabalho submetido à Revista Pai Inácio de Literatura e ...
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2016
Ca(2+) influx via store-operated Ca(2+) release activated Ca(2+) (CRAC) channels represents a main signalling pathway for a variety of cell functions, including T-cell activation as well as mast-cell degranulation. Depletion of [Ca(2+)]ER results in activation of Ca(2+) channels within the plasmamembrane that mediate sustained Ca(2+) influx which is ...
Irene, Frischauf +3 more
openaire +2 more sources
Ca(2+) influx via store-operated Ca(2+) release activated Ca(2+) (CRAC) channels represents a main signalling pathway for a variety of cell functions, including T-cell activation as well as mast-cell degranulation. Depletion of [Ca(2+)]ER results in activation of Ca(2+) channels within the plasmamembrane that mediate sustained Ca(2+) influx which is ...
Irene, Frischauf +3 more
openaire +2 more sources

