Results 121 to 130 of about 29,387 (258)

The Association Between Disordered Eating and Sleep in Non‐Clinical Populations—A Systematic Review and Meta‐Analysis

open access: yesJournal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Sleep and disordered eating behaviours may be linked through physiological and psychological mechanisms; yet, no review has systematically investigated the relationship between different sleep indicators and disordered eating behaviours and cognitions outside a clinical context.
Marie‐Christine Opitz   +49 more
wiley   +1 more source

A comparative analysis of the distribution of immunoreactive orexin A and B in the brains of nocturnal and diurnal rodents

open access: yesBehavioral and Brain Functions, 2007
Background The orexins (hypocretins) are a family of peptides found primarily in neurons in the lateral hypothalamus. Although the orexinergic system is generally thought to be the same across species, the orexins are involved in behaviors which show ...
Nixon Joshua P, Smale Laura
doaj   +1 more source

One Single Session to Sleep Them All? The Potential of Single‐Session Interventions for Insomnia

open access: yesJournal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Poor sleep and insomnia are pervasive public health concerns, with insomnia ranking as the second most prevalent mental health disorder in the general population. Moreover, insomnia is a significant predictor of subsequent depression and is frequently co‐occurring with other psychological difficulties.
Matteo Carpi   +2 more
wiley   +1 more source

The Effects of Daridorexant on Patients With Comorbid Insomnia Disorder and Untreated Mild Obstructive Sleep Apnoea: A Post Hoc Subgroup Analysis of a Phase 3, Randomised Clinical Trial

open access: yesJournal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Daridorexant, a dual orexin receptor antagonist, is approved for the treatment of insomnia disorder in adults. Approximately 30%–35% of patients with insomnia disorder also have obstructive sleep apnoea (OSA) of any severity. It is unclear whether sleep medications provide safe and effective treatment for insomnia in these patients.
Christopher J. Lettieri   +8 more
wiley   +1 more source

Management of Insomnia Complaints by Non‐Sleep Specialist Physicians: A French DELPHI Consensus

open access: yesJournal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Insomnia is the most prevalent sleep disorder and a major public health concern, affecting chronically up to 19% of the adult population in France. Despite its significant impact on quality of life, mental health, and cardiometabolic disease, insomnia disorder remains underdiagnosed and inadequately managed.
Pierre‐Alexis Geoffroy   +6 more
wiley   +1 more source

Characterization of a putative orexin receptor in Ciona intestinalis sheds light on the evolution of the orexin/hypocretin system in chordates

open access: yesScientific Reports
Tunicates are evolutionary model organisms bridging the gap between vertebrates and invertebrates. A genomic sequence in Ciona intestinalis (CiOX) shows high similarity to vertebrate orexin receptors and protostome allatotropin receptors (ATR).
Maiju K. Rinne   +7 more
doaj   +1 more source

Age at Onset and Delays in Diagnosis of Central Disorders of Hypersomnolence Over the Past 30 Years

open access: yesJournal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Patients with narcolepsy type 1 (NT1), type 2 (NT2), idiopathic hypersomnia (IH) usually suffer from symptoms for years, even decades, before being diagnosed. We aimed to assess age at onset, age at diagnosis and changes in the diagnostic delays of these patients from 1990 to 2020 in a single centre.
Zhongxing Zhang   +4 more
wiley   +1 more source

Research progress of narcolepsy

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2017
The discovery of hypothalamus Hypocretin (Hcrt)/Orexin system and its relationship with narcolepsy is one of the major advances in sleep medicine. Hcrt/Orexin is a significant neurotransmitter in the circadian cycle of arousal.
Fu-long XIAO, Jun ZHANG, Fang HAN
doaj  

The Number of Newly Dispensed Hypnotic Drugs During the First COVID‐19 Lockdown Period in The Netherlands

open access: yesJournal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT The 2019 coronavirus (COVID‐19) pandemic and associated lockdowns significantly disrupted healthcare systems, including access to pharmacological treatments such as sleep medication. This study investigated the number of first‐time dispensed hypnotic drugs during the first COVID‐19 lockdown in the Netherlands, using data from the Dutch ...
Dana M. Dijkgraaf   +5 more
wiley   +1 more source

Longitudinal association between sleep and Alzheimer's pathology

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Since sleep disturbance is a modifiable risk factor for Alzheimer's disease (AD), we tested associations between sleep and AD pathology in cognitively unimpaired (CU) persons. METHODS We included 223 participants from the PREVENT‐AD cohort with self‐reported measures of sleep, objective actigraphy measures of sleep, and positron ...
Bery Mohammediyan   +13 more
wiley   +1 more source

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