Results 101 to 110 of about 29,596 (259)

Defining the organizational structure of dopamine and muscarninic acetylcholine receptors [PDF]

, 2015
No abstract ...
Alvarez-Curto, Elisa, Caltabiano, Gianluigi Caltabiano, Liste, María José Varela, Marsango, Sara, Milligan, Graeme   +4 more
core   +1 more source

Investigation of the “Not Better Explained” Diagnosis Criteria in Sleep Disorder Classifications: A Systematic Content Analysis and Critical Review

Journal of Sleep Research, EarlyView.
The “Not Better Explained” (NBE) criterion plays a key role in preventing diagnostic misclassification by structuring causal reasoning in sleep medicine. This systematic content analysis compares the use, wording, and excluded conditions of NBE criteria across the ICSD‐3‐TR and DSM‐5‐TR for ten major sleep disorders.
Jean‐Arthur Micoulaud‐Franchi, Vincent P. Martin, Julien Coelho, Régis Lopez, Pierre‐Alexis Geoffroy, Laure Peter‐Derex, Isabelle Lambert, Charles M. Morin, Clélia Quiles, Christophe Gauld   +9 more
wiley   +1 more source

Pharmacological and chemogenetic orexin/hypocretin intervention ameliorates Hipp-dependent memory impairment in the A53T mice model of Parkinson’s disease

Molecular Brain, 2019
Parkinson’s disease (PD), classically defined as a progressive motor disorder accompanied with dopaminergic neuron loss and presence of Lewy bodies, is the second most common neurodegenerative disease.
Milos Stanojlovic, Jean Pierre Pallais, Michael K. Lee, Catherine M. Kotz   +3 more
doaj   +1 more source

Comparative effects of hypnotic agents on sleep architecture and respiratory outcomes in obstructive sleep apnea: A systematic review and network meta‐analysis

Psychiatry and Clinical Neurosciences, EarlyView.
Aim This network meta‐analysis of randomized controlled trials (RCTs) aimed to investigate which hypnotics are associated with the most favorable sleep architecture and respiratory outcomes in adults with obstructive sleep apnea. Methods Primary outcomes included total sleep time (TST) and apnea–hypopnea index (AHI) during TST.
Taro Kishi, Toshikazu Ikuta, Kenji Sakuma, Masakazu Hatano, Tatsuhiko Kishi, Tsuyoshi Kitajima, Nakao Iwata   +6 more
wiley   +1 more source

The role of orexin A in the pathogenesis of ischaemic stroke at high altitude

Experimental Physiology
Orexin offers protection against cerebral ischaemia–reperfusion injury, with high altitude playing a key role in modulating its expression. This study aimed to investigate the effect of high altitude on orexin expression and its pathophysiological ...
Minxia Zhu, Xu Guo, Jing Guo, Zhaojun Zhang, Kexin Zhang, Yaqi Lei, Yuhe Wang, Haoshuang Zhan   +7 more
doaj   +1 more source

The Effect of Porcine Orexin a on Glucose-Dependent Insulinotropic Polypeptide Plasma Concentrations in Pigs

European Journal of Inflammation, 2010
The orexigenic system was discovered in 1998. It consists of two neuropeptides, Orexin A and Orexin B. Researchers have focused more on Orexin A, since its intracerebroventricular injection into the lateral ventricle of the rat's brain causes an increase
P. Papakonstantinou, N. Tziris, D. Kapoukranidou, A. Gotzamani-Psarrakou, C.H.R. Tsonidis, M.N. Patsikas, G. Papazoglou   +6 more
doaj   +1 more source

Melanin-Concentrating Hormone (MCH): Role in REM Sleep and Depression. [PDF]

, 2015
The melanin-concentrating hormone (MCH) is a peptidergic neuromodulator synthesized by neurons of the lateral sector of the posterior hypothalamus and zona incerta.
Benedetto, Luciana, Chase, Michael H, Lagos, Patricia, López-Hill, Ximena, Monti, Jaime M, Pascovich, Claudia, Scorza, Cecilia, Torterolo, Pablo, Urbanavicius, Jessika   +8 more
core   +3 more sources

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

Context‐Dependent Temporal Changes in Hypnotics Involved in Suicide Attempts

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Temporal changes in hypnotics involved in suicide attempts showed context‐dependent shifts. Dual orexin receptor antagonists increased significantly, while benzodiazepine involvement declined only in overdose‐related attempts. Melatonin receptor agonists showed no significant trend during 2020.
Taro Sasaki, Norio Sugawara, Motoharu Furukawa, Hirotaka Iwaki, Shiro Suda, Norio Yasui‐Furukori   +5 more
wiley   +1 more source

Paradoxical function of orexin/hypocretin circuits in a mouse model of Huntington's disease

Neurobiology of Disease, 2011
Huntington's disease (HD) is a neurodegenerative disorder involving progressive motor disturbances, cognitive decline, and desynchronized sleep–wake rhythms.
Rhîannan H. Williams, A. Jennifer Morton, Denis Burdakov   +2 more
doaj   +1 more source