Results 81 to 90 of about 29,596 (259)

Chronic Insomnia and Excess Cannabis Ingestion in an Older Adult—A Clinical Report of Complex Geriatric Care

Journal of the American Geriatrics Society, EarlyView.
Cannabis use in older adults may have a broad range of effects in older adults impacting Mind, Mobility, Medications, Multi‐complexity, and what Matters Most.
Erik Fraunberger, Maia von Maltzahn
wiley   +1 more source

Exogenous Orexin-A Microinjected Into Central Nucleus of the Amygdala Modulates Feeding and Gastric Motility in Rats

Frontiers in Neuroscience, 2020
Orexin-A is a circulating neuropeptide and neurotransmitter that regulates food intake and gastric motility. The central nucleus of the amygdala (CeA), which regulates feeding behavior and gastric function, expresses the orexin-1 receptor.
Tingting Jin, Zhongxin Jiang, Xiao Luan, Zhuling Qu, Feifei Guo, Shengli Gao, Luo Xu, Xiangrong Sun   +7 more
doaj   +1 more source

Separaxion anxiety in pediatric migraine without aura: A pilot study [PDF]

, 2017
Background: Separation anxiety (SA) can be defined as the fear reaction and protest manifested by children when the main caregivers move away from him/her or in front of unfamiliar person. SA near eight months may be considered as an important and normal
Di Filippo T., Di Folco A., Gabriele Tripi, Maltese A., Parisi L., Romano P., Salerno M.   +6 more
core   +1 more source

Chronic insomnia, REM sleep instability and emotional dysregulation: A pathway to anxiety and depression?

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary The world‐wide prevalence of insomnia disorder reaches up to 10% of the adult population. Women are more often afflicted than men, and insomnia disorder is a risk factor for somatic and mental illness, especially depression and anxiety disorders.
Dieter Riemann, Raphael J. Dressle, Fee Benz, Kai Spiegelhalder, Anna F. Johann, Christoph Nissen, Elisabeth Hertenstein, Chiara Baglioni, Laura Palagini, Lukas Krone, Michael L. Perlis, Katharina Domschke, Mathias Berger, Bernd Feige   +13 more
wiley   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Reactivation of hyperglycemia-induced hypocretin (HCRT) gene silencing by N-acetyl-d-mannosamine in the orexin neurons derived from human iPS cells

Epigenetics, 2017
Orexin neurons regulate critical brain activities for controlling sleep, eating, emotions, and metabolism, and impaired orexin neuron function results in several neurologic disorders.
Koji Hayakawa, Yasuharu Sakamoto, Osamu Kanie, Atsuko Ohtake, Shusaku Daikoku, Yukishige Ito, Kunio Shiota   +6 more
doaj   +1 more source

Presence of orexin A and orexin 1 receptor in the buffalo prostate

Italian Journal of Animal Science, 2010
The orexins A and B are two peptides discovered initially in the rat lateral hypothalamus involved in the regulation of some body functions such as food intake, sleep/wake cycle, arterial pressure and heart rate. They interact with two receptors defined &
A. Vittoria, F. Russo, G. Petrosino
doaj   +1 more source

Ageing‐related modification of sleep and breathing in orexin‐knockout narcoleptic mice

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Narcolepsy type‐1 (NT1) is a lifelong sleep disease, characterised by impairment of the orexinergic system, with a typical onset during adolescence and young adulthood. Since the wake–sleep cycle physiologically changes with ageing, this study aims to compare sleep patterns between orexin‐knockout (KO) and wild type (WT) control mice at ...
Stefano Bastianini, Sara Alvente, Chiara Berteotti, Viviana Lo Martire, Gabriele Matteoli, Elena Miglioranza, Alessandro Silvani, Giovanna Zoccoli   +7 more
wiley   +1 more source

Differential roles of orexin receptors in the regulation of sleep/wakefulness

Frontiers in Endocrinology, 2013
Orexin A and orexin B are hypothalamic neuropeptides that play critical roles in the regulation of sleep/wakefulness, as well as in a variety of physiological functions such as emotion, reward, and energy homeostasis.
Michihiro eMieda, Natsuko eTsujino, Takeshi eSakurai   +2 more
doaj   +1 more source

ATP-Sensitive Potassium Channel-Mediated Lactate Effect on Orexin Neurons: Implications for Brain Energetics during Arousal [PDF]

, 2010
Active neurons have a high demand for energy substrate, which is thought to be mainly supplied as lactate by astrocytes. Heavy lactate dependence of neuronal activity suggests that there may be a mechanism that detects and controls lactate levels and/or ...
Hirasawa, Michiru, Parsons, Matthew P.
core   +1 more source