Results 71 to 80 of about 29,596 (259)

Neural pathways from hypothalamic orexin neurons to the ventrolateral preoptic area mediate sleep impairments induced by conditioned fear

Frontiers in Neuroscience, 2023
IntroductionFear and sleep impairments common co-exist, but the underlying mechanisms remain unclear. Hypothalamic orexinergic neurons are involved in the regulation of sleep-wake and fear expression.
Caifen Ma, Caifen Ma, Ning Zhou, Kang Ma, Kang Ma, Jiandong Niu, Jiandong Niu, Ting Mi, Ting Mi, Zhenquan He, Yujun Wen, Yujun Wen, Chunhong Liu, Chunhong Liu, Zhongyi He, Jianguo Niu, Jianguo Niu   +16 more
doaj   +1 more source

Eating and feeding disorders in pediatric age [PDF]

, 2018
Eating and feeding disorders are common in pediatric age and may be important to discover and recover the early symptoms in order to optimize the treatment and ...
Cerroni F., Chisari M. G., D'Oro L., Di Folco A., Franco S., Gallai B., Geraci D., Lavano F., Lavano S. M., Magliulo R. M., Marotta R., Murabito P., Parisi L., Picciocchi E., Polito A. N., Romano P., Russo D., Salerno M., Sorrentino M., Testa D., Tripi G.   +20 more
core   +1 more source

The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease

Brain Pathology, EarlyView.
SIDT2‐immunoreactive inclusions are observed in the striatum, cerebral cortex, and hypothalamus in HD cases with different Vonsattel grades, and the frequency of SIDT2‐immunoreactive inclusions is associated with longer CAG repeats in the huntingtin gene.
Sanaz Gabery, Sofia Bergh, Chrisovalantou Huridou, Rachel Y. Cheong, Barbara Baldo, Paul Günther Scheunemann, Marie‐Louisa Schoebel, Linda Holmquist Mengelbier, Elisabet Englund, Catriona McLean, Carsten Saft, Deniz Kirik, Maria Björkqvist, Glenda Halliday, Elisabeth Petrasch‐Parwez, Huu Phuc Nguyen, Jonasz Jeremiasz Weber, Åsa Petersén   +17 more
wiley   +1 more source

Sleep Disorders and Genes [PDF]

, 2019
Versão preprintThe sleep-wake cycle is a neurobiological phenomenon that shows intervals of activity alternating with restfulness that appears with a periodicity approximating the 24h day-night cycle.
Amici, Amin, Ban, Barbagallo, Basheer, Borbely, Brando, Brower, Byrne, Cade, Cade, Carskadon, Chaki, Chang, Chase, Chatterjee, Chen, Cohen, Cohen, Dall’Ara, de Lima, Dement, Dijk, Dong, Evans, Franco-Tormo, Fuh, Gan-Or, Gillombardo, Gottesmann, Gottesmann, Guilleminault, Han, Hennessy, Hirotsu, Hobson, Hobson, Hu, Huang, Huang, Jinek, Johansson, Keenan, Khan, Li, Lin, Lind, Luo, Lusk, Mahowald, Mendlewicz, Mistlberger, Miyagawa, Monti, Murillo-Rodríguez, Naiman, Nir, Nishino, Nordgren, Ollila, Pace-Schott, Palagini, Panda, Pandi-Perumal, Parish, Parmeggiani, Parsons, Patel, Peirano, Petit, Posner, Potter, Rechtschaffen, Riddle, Rizzo, Roffwarg, Scammell, Scherer, Serretti, Serretti, Shalem, Siclari, Siegel, Spada, Subramani, Szentkirályi, Tafti, Torterolo, Torterolo, Torterolo, Torterolo, Torterolo, Toth, Toyoda, Truong, Turek, Utge, van Maanen, Videnovic, Von Economo, Wu, Yong   +101 more
core   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Differential Roles of Each Orexin Receptor Signaling in Obesity

iScience, 2019
Summary: Orexins are hypothalamic neuropeptides that regulate feeding, energy expenditure, and sleep. Although orexin-deficient mice are susceptible to obesity, little is known about the roles of the orexin receptors in long-term energy metabolism. Here,
Miyo Kakizaki, Yousuke Tsuneoka, Kenkichi Takase, Staci J. Kim, Jinhwan Choi, Aya Ikkyu, Manabu Abe, Kenji Sakimura, Masashi Yanagisawa, Hiromasa Funato   +9 more
doaj   +1 more source

The neurobiology of circadian rhythms [PDF]

, 2009
Purpose of review There is growing awareness of the importance of circadian rhythmicity in various research fields. Exciting developments are ongoing in the field of circadian neurobiology linked to sleep, food intake, and memory.
Boersma, Gretha J.,, Hut, Roelof A.,, Zee, Eddy A. van der,   +2 more
core   +3 more sources

Stapled truncated orexin peptides as orexin receptor agonists

Peptides, 2018
The peptides orexin-A and -B, the endogenous agonists of the orexin receptors, have similar 19-amino-acid C-termini which retain full maximum response as truncated peptides with only marginally reduced potency, while further N-terminal truncations successively reduce the activity.
Karhu, L, Weisell, J, Turunen, PM, Leino, TO, Pätsi, H, Xhaard, H, Kukkonen, JP, Wallén, EAA   +7 more
openaire   +5 more sources

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Pancreatic exocrine insufficiency after bariatric surgery [PDF]

, 2017
Morbid obesity is a lifelong disease, and all patients require complementary follow-up including nutritional surveillance by a multidisciplinary team after bariatric procedures.
Arnelo, Urban, Haas, Stephan L., Löhr, J. -Matthias, Martin, Lena, Rutkowski, Wiktor, Thorell, Anders, Valente, Roberto, Vujasinovic, Miroslav   +7 more
core   +1 more source