Results 121 to 130 of about 18,205 (239)

Research progress of narcolepsy

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2017
The discovery of hypothalamus Hypocretin (Hcrt)/Orexin system and its relationship with narcolepsy is one of the major advances in sleep medicine. Hcrt/Orexin is a significant neurotransmitter in the circadian cycle of arousal.
Fu-long XIAO, Jun ZHANG, Fang HAN
doaj  

Early adversity and the comorbidity between metabolic disease and psychopathology

open access: yesThe Journal of Physiology, Volume 604, Issue 11, Page 4338-4377, 1 June 2026.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas   +1 more
wiley   +1 more source

Oxytocin‐ und Vasopressin‐Photosonden zur Entschlüsselung der Neuropeptid‐Signalgebung mit hoher räumlicher und zeitlicher Präzision

open access: yesAngewandte Chemie, Volume 138, Issue 22, 25 May 2026.
Neue biokompatible Oxytocin‐ und Vasopressin‐Photosonden mit modernsten Photocages. Diese Photosonden sind inaktiv und können mit spezifischen Lichtwellen entschützt werden, was eine Rezeptoraktivierung mit hoher zeitlicher und räumlicher Kontrolle ermöglicht. Abbildung erstellt mit https://BioRender.com ZUSAMMENFASSUNG Das Oxytocin/Vasopressin (OT/VP)
Konstantin Raabe   +7 more
wiley   +1 more source

Relationship Between Cognitive Impairments and Serum Orexin Levels in Epilepsy Patients

open access: yesArchives of Epilepsy
Objective: Recent studies on neurodegenerative diseases have indicated that Orexin A plays a role in cognitive impairment. Furthermore, animal studies have demonstrated that Orexin A enhances synaptic plasticity in the hippocampus.
Zeliha Yücel   +4 more
doaj   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 22, 25 May 2026.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe   +7 more
wiley   +1 more source

Narcolepsy initially misdiagnosed as schizophrenia: A case report

open access: yes
Sleep Research, Volume 3, Issue 2, Page 180-184, June 2026.
Feng Daoyi, Liu Xin, Xu Rui, He Lihua
wiley   +1 more source

Novel class of medications, orexin receptor antagonists, in the treatment of insomnia – critical appraisal of suvorexant

open access: yes, 2016
Jessica L Norman, Sarah L Anderson Department of Clinical Pharmacy, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA Abstract: Insomnia, a highly prevalent disorder, can be detrimental to patients’
Norman JL, Anderson SL
core  

Microinjection of Orexin-A into the Locus Coeruleus Area Induces Morphine Withdrawal Behaviors in Morphine Independent Rats

open access: yesResearch on Addiction, 2012
Introduction: Orexin neuropeptide has a role in opioid withdrawal behaviors. Orexin-expressing neurons that are present in the hypothalamic nuclei send dense projections to the Locus Coeruleus (LC).
Hosin Azizi   +2 more
doaj  

Antistress effects of Kampo medicine "Yokukansan" via regulation of orexin secretion

open access: yesNeuropsychiatric Disease and Treatment, 2017
Haruto Katahira,1 Masataka Sunagawa,1 Daishi Watanabe,1,2 Yasuaki Kanada,1,3 Ayami Katayama,1 Risa Yamauchi,1 Masashi Takashima,4 Shintaro Ishikawa,1 Tadashi Hisamitsu1 1Department of Physiology, 2Department of Neurology, School of Medicine, Showa ...
Katahira H   +8 more
doaj  

Molecular cloning of medaka orexin and orexin receptor and decreased spontaneous movement in response to an orexin inhibitor [PDF]

open access: yes
Orexin (hypocretin) is a neuropeptide secreted by hypothalamic neurons that is activated duringmotivating behaviors and active waking. Our knowledge of orexin is mainly limited to mammalian species, such ashumans, mice, and rats. In the present study, we
Itagaki, Shirou   +6 more
core  

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