Results 41 to 50 of about 29,387 (258)

Psychopathological and psychodynamic hypotheses for pediatric stuttering [PDF]

, 2018
Stuttering is a common language alteration in pediatric age consisting in repetitions and blocks, which entail a break in the rhythm and melody of the speech.
Cerroni F., Chisari M. G., D'Oro L., Di Folco A., Franco S., Gallai B., Geraci D., Giugliano P., Grieco M., Lavano F., Lavano S. M., Magliulo R. M., Marotta R., Marsala G., Murabito P., Parisi L., Picciocchi E., Polito A. N., Romano P., Russo D., Salerno M., Sorrentino M., Testa D., Tripi G.   +23 more
core   +1 more source

Acute optogenetic silencing of orexin/hypocretin neurons induces slow wave sleep in mice [PDF]

, 2011
Orexin/hypocretin neurons have a crucial role in the regulation of sleep and wakefulness. To help determine how these neurons promote wakefulness, we generated transgenic mice in which orexin neurons expressed halorhodopsin (orexin/Halo mice), an orange ...
Boyden, Edward Stuart, Kilduff, Thomas S., Takahashi, Satoru, Tominaga, Makoto, Tsunematsu, Tomomi, Yamanaka, Akihiro   +5 more
core   +1 more source

Orexins and stress [PDF]

Frontiers in Neuroendocrinology, 2018
The neuropeptides orexins are important in regulating the neurobiological systems that respond to stressful stimuli. Furthermore, orexins are known to play a role many of the phenotypes associated with stress-related mental illness such as changes in cognition, sleep-wake states, and appetite.
Laura A, Grafe, Seema, Bhatnagar
openaire   +2 more sources

Functional cardiac orexin receptors: role of orexin-B/orexin 2 receptor in myocardial protection [PDF]

Clinical Science, 2018
Orexins/hypocretins exert cardiovascular effects which are centrally mediated. In the present study, we tested whether orexins and their receptors may also act in an autocrine/paracrine manner in the heart exerting direct effects. Quantitative reverse transcription-PCR (RT-PCR), immunohistochemical and Western blot analyses revealed that the rat heart ...
Patel, V, Karteris, E, Chen, J, Kyrou, I, Mattu, H, Dimitriadis, G, Rodrigo, G, Antoniades, C, Antonopoulos, A, Tan, B, Hillhouse, E, Ng, A, Randeva, H   +12 more
openaire   +7 more sources

Neuropsychomotricity in water: A new rehabilitative tool for neruodevelop-mental disorders [PDF]

, 2018
Neuropsychomotricity in water is a rehabilitative practice that avails itself just of the liquid element, as a mediator of relationships: in water yes they upset all dynamics, be they relational, of equilibrium, of movement and perception, due to the ...
Cerroni F., Chisari M. G., D'Oro L., Di Folco A., Franco S., Gallai B., Geraci D., Lavano F., Lavano S. M., Magliulo R. M., Marotta R., Marsala G., Murabito P., Parisi L., Picciocchi E., Polito A. N., Romano P., Ruberto M., Russo D., Salerno M., Sorrentino M., Testa D., Tripi G.   +22 more
core   +1 more source

Activation of orexin-2 receptors in the Kӧlliker-Fuse nucleus of anesthetized mice leads to transient slowing of respiratory rate

Frontiers in Physiology, 2022
Orexins are neuropeptides originating from the hypothalamus that serve broad physiological roles, including the regulation of autonomic function, sleep-wake states, arousal and breathing.
Adrienn G. Varga, Adrienn G. Varga, Jessica R. Whitaker-Fornek, Jessica R. Whitaker-Fornek, Sebastian N. Maletz, Erica S. Levitt, Erica S. Levitt   +6 more
doaj   +1 more source

Expression and potential role of the peptide orexin-A in prostate cancer [PDF]

, 2015
The peptides orexin-A and orexin-B and their G protein-coupled OX1 and OX2 receptors are involved in multiple physiological processes in the central nervous system and peripheral organs.
ASSISI, LOREDANA, Campese, R, COSTAGLIOLA, ANNA, Forte, M, IACHETTA, GIUSEPPINA, LIGUORI, GIOVANNA, MIRABELLA, NICOLA, Monaco, R, PAVONE, LUIGI MICHELE, TAFURI, SIMONA, VALIANTE, Salvatore, VITTORIA, ALFREDO   +11 more
core   +1 more source

Increased Numbers of CD4+ T‐Cells in the Hypocretin/Orexin Region of Narcolepsy Type 1

Annals of Neurology, EarlyView.
Narcolepsy type 1 (NT1) is presumed to be an autoimmune disorder caused by hypothalamic loss of hypocretin (Hcrt; orexin). In postmortem NT1 brains, we observed an 11‐fold increase of CD4+ T‐cells in the Hcrt region compared with control hypothalami, without a corresponding rise in CD8+ T‐cells.
Ling Shan, Milo Fonville, Mabel Hoekstra, Rolf Fronczek, Joost Smolders, Dick F. Swaab   +5 more
wiley   +1 more source

Orexin-A Exerts Neuroprotective Effects via OX1R in Parkinson’s Disease

Frontiers in Neuroscience, 2018
Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by progressive and selective death of dopaminergic neurons. Orexin-A is involved in many biological effects of the body.
Mei-Fang Liu, Mei-Fang Liu, Yan Xue, Cui Liu, Yun-Hai Liu, Hui-Ling Diao, Ying Wang, Yi-Peng Pan, Lei Chen   +8 more
doaj   +1 more source

Selective loss of GABAB receptors in orexin/hypocretin-producing neurons results in disrupted sleep/wakefulness architecture [PDF]

, 2007
We generated mice with a selective loss of GABAB receptors in orexin neurons. Orexin neurons in these GABAB1^-/-(orexin) mice showed reduced responsiveness to GABA_A receptor agonists due to a ...
Bernard Bettler, Hitomi Takahira, Ken-ichi Yagami, Masashi Yanagisawa, Mika Nomiyama, Noriko Hirashima, Satoru Takahashi, Satoshi Kunita, Taizo Matsuki, Takeshi Sakurai, Thomas Kilduff   +10 more
core   +1 more source