Results 71 to 80 of about 29,387 (258)

Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction. [PDF]

, 2013
The neurochemical changes underlying human emotions and social behaviour are largely unknown. Here we report on the changes in the levels of two hypothalamic neuropeptides, hypocretin-1 and melanin-concentrating hormone, measured in the human amygdala ...
Behnke, Eric J, Blouin, Ashley M, Fried, Itzhak, Karlsson, Karl Æ, Lam, Hoa A, Lapierre, Jennifer L, Maidment, Nigel T, Siegel, Jerome M, Staba, Richard J, Wilson, Charles L   +9 more
core   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Reactivation of hyperglycemia-induced hypocretin (HCRT) gene silencing by N-acetyl-d-mannosamine in the orexin neurons derived from human iPS cells

Epigenetics, 2017
Orexin neurons regulate critical brain activities for controlling sleep, eating, emotions, and metabolism, and impaired orexin neuron function results in several neurologic disorders.
Koji Hayakawa, Yasuharu Sakamoto, Osamu Kanie, Atsuko Ohtake, Shusaku Daikoku, Yukishige Ito, Kunio Shiota   +6 more
doaj   +1 more source

The neurobiology of circadian rhythms [PDF]

, 2009
Purpose of review There is growing awareness of the importance of circadian rhythmicity in various research fields. Exciting developments are ongoing in the field of circadian neurobiology linked to sleep, food intake, and memory.
Boersma, Gretha J.,, Hut, Roelof A.,, Zee, Eddy A. van der,   +2 more
core   +3 more sources

The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease

Brain Pathology, EarlyView.
SIDT2‐immunoreactive inclusions are observed in the striatum, cerebral cortex, and hypothalamus in HD cases with different Vonsattel grades, and the frequency of SIDT2‐immunoreactive inclusions is associated with longer CAG repeats in the huntingtin gene.
Sanaz Gabery, Sofia Bergh, Chrisovalantou Huridou, Rachel Y. Cheong, Barbara Baldo, Paul Günther Scheunemann, Marie‐Louisa Schoebel, Linda Holmquist Mengelbier, Elisabet Englund, Catriona McLean, Carsten Saft, Deniz Kirik, Maria Björkqvist, Glenda Halliday, Elisabeth Petrasch‐Parwez, Huu Phuc Nguyen, Jonasz Jeremiasz Weber, Åsa Petersén   +17 more
wiley   +1 more source

Room Temperature Synthesis and Antibacterial Activity of New Sulfonamides Containing N,N -Diethyl-Substituted AmidoMoieties [PDF]

, 2012
Sulfonamide drugs which have brought about an antibiotic revolution in medicine are associated with a wide range of biological activities.
Ajani, Olayinka O., Echeme, Johnbull O, Familoni, Oluwole B, Sujiang, Zheng, Wu, Feipeng   +4 more
core   +5 more sources

Stapled truncated orexin peptides as orexin receptor agonists

Peptides, 2018
The peptides orexin-A and -B, the endogenous agonists of the orexin receptors, have similar 19-amino-acid C-termini which retain full maximum response as truncated peptides with only marginally reduced potency, while further N-terminal truncations successively reduce the activity.
Karhu, L, Weisell, J, Turunen, PM, Leino, TO, Pätsi, H, Xhaard, H, Kukkonen, JP, Wallén, EAA   +7 more
openaire   +5 more sources

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

A brief review about anxiety and aggressive behavior in pediatric age [PDF]

, 2018
Anxiety can be considered a normal experience of the human being and as such also of the child. It manifests itself in different ways according to the level of development: in the smaller the child, the more anxiety is expressed with manifestations that ...
Cerroni F., Chisari M. G., Cibelli G., Di Folco A., Franco S., Gallai B., Geraci D., Giugliano P., Grieco M., Lavano F., Lavano S. M., Magliulo R. M., Marotta R., Marsala G., Montana A., Murabito P., Parisi L., Picciocchi E., Polito A. N., Ro L., Romano P., Russo D., Salerno M., Sorrentino M., Testa D., Tripi G., Valenzano A.   +26 more
core  

ADDICTIONS SUBSTANCE FREE DURING LIFESPAN [PDF]

, 2018
The addictions substance free is an umbrella definition comprises internet addiction, sexual addiction, gambling pathological, workholism, videogames and computer addiction. Actually, the technological addictions is frequent in young adolescents.
ANGELO MONTANA, ANNA NUNZIA POLITO, ANNABELLA DI FOLCO, BEATRICE GALLAI, DANIELA RUSSO, DAVIDE TESTA, DIEGO GERACI, ELISABETTA PICCIOCCHI, FRANCESCO CERRONI, FRANCESCO LAVANO, FRANCESCO SESSA, GABRIELE TRIPI, GABRIELLA MARSALA, LUCIA PARISI, LUCREZIA D’ORO, MARGHERITA SALERNO, MARIO GIUSEPPE CHISARI, MICHELE SORRENTINO, MONICA SALERNO, PALMIRA ROMANO, PAOLO MURABITO, PASQUALE GIUGLIANO, ROSA MAROTTA, ROSARIA MARTINA MAGLIULO, SABRINA FRANCO, SERENA MARIANNA LAVANO   +25 more
core   +1 more source